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Gene Families

A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.

The following families, defined by the HUGO Gene Nomenclature CommitteeThis link leads to a site outside Genetics Home Reference., are included in Genetics Home Reference.

    • ABC (ATP-binding cassette transporters)
    • ABHD (abhydrolase domain containing genes)
    • ADAMTS (ADAMTS metallopeptidase with thrombospondin type 1 motif family)
    • ALDH (aldehyde dehydrogenases)
    • ATP (ATPase superfamily)
    • blood group (blood group determining genes)
    • CACN (calcium channels)
    • CD (CD molecules)
    • COLPG (collagen proteoglycans)
    • CYP (cytochrome P450)
    • DNAJ (DnaJ (Hsp40) homologs)
    • FOX (Forkhead box genes)
    • GPC (glypicans)
    • GPR (G protein-coupled receptors)
    • IFT (intraflagellar transport homologs)
    • KCN (potassium channels)
    • KRT (keratins)
    • NLR (nucleotide-binding domain and leucine rich repeat containing family)
    • PAX (paired box gene)
    • PTP (protein tyrosine phosphatases)
    • RPS (ribosomal proteins)
    • SCN (sodium channels)
    • SLC (solute carriers)
    • TNFSF (Tumor necrosis factor (ligand) superfamily)
    • TRIM (tripartite motif-containing)
    • USP (ubiquitin-specific peptidases)
    • WNT (wingless-type MMTV integration site family)
    • ZFYVE (zinc fingers, FYVE-type)
    • ZNF (zinc fingers, C2H2-type)
Published: January 23, 2009