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A textbook of immunology for undergraduates
that follows the immune response to infection from innate immunity to the adaptive immune response
and immune memory.
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Paperback, 387 pages,
367 full-color illustrations
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New interviews with leading immunologists
Siamon Gordon on the Roles of Macrophages and Polly Matzinger on Tolerance and Immunity – see previews
NEW for qualifying instructors –
2007-2008 online updates
New sections on Tracking Immune Responses In Vivo, Epstein–Barr Virus and Malaria, Updated References for the whole book.
Immunity is an introduction for undergraduates and medical students to the immune response to
infection, with a major chapter on innate immunity that allows the later chapters on the activation
and effector actions of lymphocytes to illustrate how adaptive immune responses are built on innate
mechanisms. It includes chapters on lymphocyte development and on specialized lymphocytes with some
innate features, and three chapters on the response to specific microorganisms that illustrate
how the mechanisms described in earlier chapters are coordinated in response to some important
human pathogens. The book concludes with chapters on immune regulation, immunological disease,
and the design of vaccines.
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| About the authors of Immunity |
Anthony L DeFranco graduated from Harvard College in biochemistry and molecular biology in 1975 and did his
PhD on bacterial chemotaxis with Daniel E Koshland Jr at the University of California at Berkeley before
turning to his present principal research interest, the activation of B lymphocytes, as a postdoctoral fellow
in the laboratory of William E Paul at NIH in 1979. He is currently Chairman of the Department of Microbiology
and Immunology at the University of California San Francisco Medical School where his research interests are
the mechanisms of signaling by the B cell antigen receptor and Toll-like receptors, and B cell autoimmunity.
Richard M Locksley graduated from Harvard College in biochemistry in 1970 and in medicine from the
University of Rochester in 1976. He was at the Moffitt Hospital in San Francisco for four years as a Medical
Resident, trained in infectious diseases at the University of Washington for three years and then returned to
the University of California in San Francisco where he served as Chief of the Division of Infectious Diseases from 1986-2004.
He is currently the Sandler Distinguished Professor of Medicine and Microbiology and Immunology, Director of the Sandler
Asthma Basic Research Center and an HHMI Investigator at UCSF. The principal focus of his research is on cellular immune
responses in infectious and inflammatory disease.
Miranda Robertson studied psychology at Birkbeck College London and at the University of Chicago in
the 1960s without graduating from either and then spent the greater part of a quarter of a century on the
editorial staff of Nature, ultimately as its Biology Editor, since when she has had the privilege of working
on behalf of Garland Publishing Inc and Current Biology Ltd with the authors of several outstanding textbooks.
She is now the Managing Director of New Science Press Ltd.
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