Reviewed March 2005
What is the official name of the NR4A2 gene?
The official name of this gene is “nuclear receptor subfamily 4, group A, member 2.”
NR4A2 is the gene's official symbol. The NR4A2 gene is also known by other names, listed below.
What is the normal function of the NR4A2 gene?
The NR4A2 gene provides instructions for making a protein found in the brain and the adrenal gland (the hormone-producing gland located on top of each kidney). In the brain, the NR4A2 protein plays a key role in prompting certain nerve cells to specialize (differentiate) and produce a chemical messenger called dopamine. Dopamine transmits messages that help the brain control physical movement and emotional behavior.
Where is the NR4A2 gene located?
Cytogenetic Location: 2q22-q23
Molecular Location on chromosome 2: base pairs 156,889,194 to 156,897,445
The NR4A2 gene is located on the long (q) arm of chromosome 2 between positions 22 and 23.
More precisely, the NR4A2 gene is located from base pair 156,889,194 to base pair 156,897,445 on chromosome 2.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about NR4A2?
You may also be interested in these resources, which are designed for genetics professionals and researchers.
- PubMed
- Recent literature
- OMIM - Genetic disorder catalog
-
What other names do people use for the NR4A2 gene or gene products?
- HZF-3
- NOT
- NR4A2_HUMAN
- nuclear receptor of T cells
- nuclear receptor related 1
- NURR1
- RNR1
- TINUR
- transcriptionally inducible nuclear receptor
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding NR4A2?
adrenal glands ;
cell ;
dopamine ;
gene ;
hormone ;
kidney ;
nerve cell ;
protein ;
receptor
You may find definitions for these and many other terms in the Genetics Home Reference
Glossary.
The resources on this site should not be used as a substitute for
professional medical care or advice. Users seeking information about
a personal genetic disease, syndrome, or condition should consult with a qualified
healthcare professional.
See How can I find a genetics professional in my area? in the Handbook.
