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UGID:141351     UniGene Hs.90280     Homo sapiens (human)   ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_863104.1 PREDICTED: similar to 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase isoform 5 C. lupus familiaris 97.0 594
XP_964054.1 bifunctional purine biosynthesis protein N. crassa 67.3 590
NP_741451.2 C55F2.1a C. elegans 65.7 419

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (1.1 pct) in cDNA library dbEST:3090, CT0213.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; intestine; uncharacterized tissue; skin; testis; mixed; embryonic tissue; eye; placenta; liver; lymph; prostate; lung; kidney; lymph node; stomach; blood; pharynx; uterus; pancreas; connective tissue; mammary gland; adrenal gland; pituitary gland; esophagus; bladder; spleen; spinal cord; thymus; bone; tonsil; larynx; ascites; bone marrow; ovary; heart; ear; cervix; muscle; thyroid; vascular; amniotic fluid; adipose tissue; mouth; umbilical cord; nerve; trachea; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_004044.5 Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA A
CR617706.1 full-length cDNA clone CS0DE005YD23 of Placenta of Homo sapiens (human) P
CR612551.1 full-length cDNA clone XCL0BB001ZD05 of Neuroblastoma of Homo sapiens (human) P
CR609807.1 full-length cDNA clone CS0DG002YA02 of B cells (Ramos cell line) of Homo sapiens (human) P
CR606023.1 full-length cDNA clone CS0DA004YL14 of Neuroblastoma of Homo sapiens (human) P
CR604622.1 full-length cDNA clone CS0DA006YB13 of Neuroblastoma of Homo sapiens (human) P
CR601137.1 full-length cDNA clone CS0DA011YC08 of Neuroblastoma of Homo sapiens (human) P
CR600478.1 full-length cDNA clone CS0DA009YG05 of Neuroblastoma of Homo sapiens (human) P
CR594366.1 full-length cDNA clone CS0DM011YA18 of Fetal liver of Homo sapiens (human) P
BC008879.2 Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, mRNA (cDNA clone MGC:15334 IMAGE:4300570), complete cds PA
AK290067.1 Homo sapiens cDNA FLJ75424 complete cds, highly similar to Human AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme (purH) mRNA A
AK313066.1 Homo sapiens cDNA, FLJ93545, highly similar to Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA
AB062403.1 Homo sapiens OK/SW-cl.86 mRNA for 5-aminoimidazole-4-carboxamide-1-bata-D-ribon ucleotid transformylase/inosinicase, complete cds PA
AK298142.1 Homo sapiens cDNA FLJ57133 complete cds, highly similar to Bifunctional purine biosynthesis protein PURH A
D89976.1 Homo sapiens mRNA for 5-aminoimidazole-4-carboxamide ribonucleotide transformylase, complete cds P
U37436.1 Human AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme (purH) mRNA, complete cds P

EST sequences (10 of 939) [Show all sequences]

AA866164.1 Clone IMAGE:1469437 uncharacterized tissue 3' read
AA984408.1 Clone IMAGE:1629931 brain 3' read PA
AI000072.1 Clone IMAGE:1608773 mammary gland 3' read PA
AA911092.1 Clone IMAGE:1519048 uncharacterized tissue 3' read PA
AI023728.1 Clone IMAGE:1654982 mixed 3' read PA
R20197.1 Clone IMAGE:34440 brain 5' read P
AI075185.1 Clone IMAGE:1673655 mixed 3' read A
AI093346.1 Clone IMAGE:1695110 uterus 3' read PA
AI093922.1 Clone IMAGE:1687987 mixed 3' read P
AI093923.1 Clone IMAGE:1687989 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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