NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Query Tips
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
dbEST
Trace Archive

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:139672     UniGene Hs.74471     Homo sapiens (human)   GJA1 Order cDNA clone, Links
Gap junction protein, alpha 1, 43kDa (GJA1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001063402.1 PREDICTED: similar to Gap junction alpha-10 protein (Connexin-57) (Cx57) R. norvegicus 55.9 270
NP_001103690.1 gap junction protein, beta 6 H. sapiens 51.0 239
NP_001010937.1 gap junction membrane channel protein beta 6 M. musculus 50.2 239

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (6.5 pct) in cDNA library dbEST:5865, HT0893.
Note: Highly represented (1.4 pct) in cDNA library dbEST:5867, HT0895.
Note: Highly represented (1.2 pct) in cDNA library dbEST:4310, CT0383.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; embryonic tissue; vascular; testis; placenta; uterus; larynx; lung; connective tissue; mouth; uncharacterized tissue; thymus; eye; mammary gland; skin; heart; bladder; adrenal gland; muscle; kidney; bone; mixed; esophagus; pancreas; thyroid; intestine; cervix; liver; pharynx; prostate; pineal gland; stomach; ear; amniotic fluid; trachea; parathyroid; bone marrow; adipose tissue; ovary; spleen; nerve; umbilical cord; lymph node; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q21-q23.2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

NM_000165.3 Homo sapiens gap junction protein, alpha 1, 43kDa (GJA1), mRNA
M65188.1 Human connexin 43 (GJA1, Cx43) mRNA, complete cds P
CR541660.1 Homo sapiens full open reading frame cDNA clone RZPDo834A1127D for gene GJA1, gap junction protein, alpha 1, 43kDa (connexin 43); complete cds, without stopcodon P
CR593006.1 full-length cDNA clone CS0DI068YP19 of Placenta Cot 25-normalized of Homo sapiens (human)
AK223289.1 Homo sapiens mRNA for connexin 43 variant, clone: SYN08454 P
AK312324.1 Homo sapiens cDNA, FLJ92636, Homo sapiens gap junction protein, alpha 1, 43kDa (connexin 43)(GJA1), mRNA
AK309490.1 Homo sapiens cDNA, FLJ99531
AK309377.1 Homo sapiens cDNA, FLJ99418
BC026329.1 Homo sapiens gap junction protein, alpha 1, 43kDa, mRNA (cDNA clone MGC:26323 IMAGE:4794131), complete cds PA
X52947.1 Human mRNA for cardiac gap junction protein P
AK294670.1 Homo sapiens cDNA FLJ50955 complete cds, highly similar to Gap junction alpha-1 protein
AK297764.1 Homo sapiens cDNA FLJ51901 complete cds, highly similar to Gap junction alpha-1 protein
AK297761.1 Homo sapiens cDNA FLJ57333 complete cds, highly similar to Gap junction alpha-1 protein
AK297402.1 Homo sapiens cDNA FLJ50990 complete cds, highly similar to Gap junction alpha-1 protein
AK295460.1 Homo sapiens cDNA FLJ53043 complete cds, highly similar to Gap junction alpha-1 protein

EST sequences (10 of 1180) [Show all sequences]

AI024670.1 Clone IMAGE:1641745 testis 3' read A
AI051881.1 Clone IMAGE:1659327 embryonic tissue 3' read A
AI061324.1 Clone IMAGE:1700762 kidney 3' read A
AI079705.1 Clone IMAGE:1669720 brain 3' read A
AI079850.1 Clone IMAGE:1659767 embryonic tissue 3' read P
AI095432.1 Clone IMAGE:1696700 uterus 3' read P
AI123921.1 Clone IMAGE:1688962 mixed 3' read P
AI123931.1 Clone IMAGE:1688963 mixed 3' read P
R23349.1 Clone IMAGE:131436 placenta 5' read
AI138681.1 Clone IMAGE:1710410 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help