Complement factor B, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (2.0 pct) in cDNA library dbEST:3558, ST0129.

Highly represented (1.8 pct) in cDNA library dbEST:4257, ST0294.

Highly represented (1.1 pct) in cDNA library dbEST:18422, LIVER1.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

liver; uterus; mammary gland; intestine; ovary; brain; stomach; lung; connective tissue; uncharacterized tissue; placenta; bladder; trachea; kidney; mixed; salivary gland; thyroid; pancreas; blood; eye; thymus; pharynx; prostate; heart; cervix; testis; muscle; ganglia; bone; spleen; adipose tissue; mouth; esophagus; adrenal gland; bone marrow; parathyroid

NCBI

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Finding cDNAs

UGID:139334 UniGene Hs.69771 Homo sapiens (human) CFB

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Complement factor B (CFB)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_860269.1	PREDICTED: similar to Complement factor B precursor (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) isoform 3	C. lupus familiaris	87.0	546

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	6
	Map position:	6p21.3

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK130533.1	Homo sapiens cDNA FLJ27023 fis, clone SLV06567, highly similar to Complement factor B precursor (EC 3.4.21.47)	P
NM_001710.5	Homo sapiens complement factor B (CFB), mRNA	A
K01566.1	Homo sapiens MHC serum complement factor B mRNA, partial cds	P
CR590439.1	full-length cDNA clone CS0DM007YO17 of Fetal liver of Homo sapiens (human)	P
CR590153.1	full-length cDNA clone CS0DM006YE21 of Fetal liver of Homo sapiens (human)	P
S67310.1	Homo sapiens complement factor B mRNA, complete cds	P
AK223400.1	Homo sapiens mRNA for complement factor B preproprotein variant, clone: FCC108A02	P
BC004143.2	Homo sapiens complement factor B, mRNA (cDNA clone MGC:1795 IMAGE:2959705), complete cds	PA
BC007990.2	Homo sapiens complement factor B, mRNA (cDNA clone MGC:4445 IMAGE:2959706), complete cds	PA
L15702.1	Human complement factor B mRNA, complete cds	P
X72875.1	H.sapiens mRNA for complement factor B	P
AK304045.1	Homo sapiens cDNA FLJ55673 complete cds, highly similar to Complement factor B precursor (EC 3.4.21.47)
AK304042.1	Homo sapiens cDNA FLJ54899 complete cds, highly similar to Complement factor B precursor (EC 3.4.21.47)
X00284.1	Human mRNA for complement factor B Ba fragment	P
J00126.1	Human MHC class III factor B gene, Bb fragment, cDNA clone fb1	P

EST sequences (10 of 808) [Show all sequences]

AA970397.1	Clone IMAGE:1573044	kidney	3' read	A
AA974115.1	Clone IMAGE:1586709	uncharacterized tissue	3' read
AA974146.1	Clone IMAGE:1585894	uncharacterized tissue	3' read	A
AA976327.1	Clone IMAGE:1589568	kidney	3' read	A
AI061409.1	Clone IMAGE:1700105	kidney	3' read	A
AI075838.1	Clone IMAGE:1675510	mixed	3' read	A
AI088735.1	Clone IMAGE:1686951	brain	3' read	PA
AA922991.1	Clone IMAGE:1520015	uncharacterized tissue	3' read	A
CB053337.1	Clone IMAGE:3291052	uncharacterized tissue	3' read	A
CB053338.1	Clone IMAGE:3291052	uncharacterized tissue	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria