Phosphoribosyl pyrophosphate synthetase 1, Homo sapiens

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Finding cDNAs

UGID:130661 UniGene Hs.56 Homo sapiens (human) PRPS1

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Phosphoribosyl pyrophosphate synthetase 1 (PRPS1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001095604.1	PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) isoform 2	M. mulatta	100.0	317
XP_521212.2	PREDICTED: hypothetical protein isoform 3	P. troglodytes	100.0	317
NP_498586.1	R151.2a	C. elegans	85.8	337
XP_955958.1	ribose-phosphate pyrophosphokinase II	N. crassa	56.8	229
NP_181082.1	ribose-phosphate pyrophosphokinase 1 / phosphoribosyl diphosphate synthetase 1 (PRSI)	A. thaliana	52.9	314
NP_651813.2	CG2246 CG2246-PE, isoform E	D. melanogaster	50.3	377

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	Expression Profile:	View expression levels using UniGene's EST ProfileViewer [Show more entries with profiles like this]
	GEO profiles:	Gene expression profiles in the NCBI Gene Expression Omnibus database
	cDNA Sources:	brain; testis; kidney; thymus; uncharacterized tissue; lung; connective tissue; embryonic tissue; trachea; ganglia; uterus; vascular; intestine; liver; eye; adrenal gland; heart; skin; prostate; mixed; muscle; bone marrow; mammary gland; spleen; blood; lymph; placenta; pancreas; stomach; cervix; lymph node; ascites; esophagus; bone; thyroid; ear; ovary; umbilical cord; salivary gland; nerve

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	X
	Map position:	Xq21.32-q24

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_002764.3	Homo sapiens phosphoribosyl pyrophosphate synthetase 1 (PRPS1), mRNA	A
CR622039.1	full-length cDNA clone CL0BB016ZA01 of Neuroblastoma of Homo sapiens (human)	P
CR606516.1	full-length cDNA clone CS0DK011YN09 of HeLa cells Cot 25-normalized of Homo sapiens (human)	P
AK223169.1	Homo sapiens mRNA for phosphoribosyl pyrophosphate synthetase 1 variant, clone: LNG09040	P
BC001605.1	Homo sapiens phosphoribosyl pyrophosphate synthetase 1, mRNA (cDNA clone MGC:2256 IMAGE:3542584), complete cds	PA
AK307748.1	Homo sapiens cDNA, FLJ97696
AK312706.1	Homo sapiens cDNA, FLJ93105, highly similar to Homo sapiens phosphoribosyl pyrophosphate synthetase 1 (PRPS1), mRNA
AK297968.1	Homo sapiens cDNA FLJ55852 complete cds, highly similar to Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1)
X15331.1	Human mRNA for phosphoribosylpyrophosphate synthetase subunit one	P
D00860.1	Homo sapiens mRNA for phosphoribosyl pyrophosphate synthetase subunit I, complete cds	P

EST sequences (10 of 875) [Show all sequences]

AA976616.1	Clone IMAGE:1585269	lung	3' read	A
AA994237.1	Clone IMAGE:1625356	mixed	3' read
AA902659.1	Clone IMAGE:1519389	uncharacterized tissue	3' read	A
AA928479.1	Clone IMAGE:1559845	intestine	3' read	A
AI040072.1	Clone IMAGE:1657655	embryonic tissue	3' read	A
R20769.1	Clone IMAGE:26210	brain	3' read
AI081675.1	Clone IMAGE:1632523	mammary gland	3' read	A
AI095095.1	Clone IMAGE:1686776	brain	3' read	A
CB053882.1	Clone IMAGE:3291156	brain	3' read
CB053883.1	Clone IMAGE:3291156	brain	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria