Phosphatase and tensin homolog, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.1 pct) in cDNA library dbEST:3557, ST0125.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

lymph node; mixed; brain; connective tissue; lung; intestine; kidney; ovary; larynx; uncharacterized tissue; placenta; vascular; ear; stomach; spleen; thymus; skin; bladder; parathyroid; pituitary gland; adipose tissue; eye; prostate; pharynx; testis; pancreas; uterus; liver; heart; embryonic tissue; thyroid; cervix; blood; muscle; mammary gland; lymph; bone; umbilical cord; tonsil; adrenal gland

NCBI

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Finding cDNAs

UGID:715625 UniGene Hs.500466 Homo sapiens (human) PTEN

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Phosphatase and tensin homolog (PTEN)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001102542.1	PREDICTED: phosphatase and tensin homolog isoform 2	M. mulatta	100.0	402
NP_477424.1	Pten CG5671-PC, isoform C	D. melanogaster	56.9	327
NP_566929.1	phosphatase-related	A. thaliana	52.0	200
NP_954869.1	transmembrane phosphatase with tensin homology isoform gamma	H. sapiens	45.1	357

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	10
	Map position:	10q23.3

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000314.4	Homo sapiens phosphatase and tensin homolog (PTEN), mRNA	A
CR450306.1	Homo sapiens full open reading frame cDNA clone RZPDo834E031D for gene PTEN, phosphatase and tensin homolog (mutated in multiple advanced cancers 1); complete cds; without stopcodon	P
CR624542.1	full-length cDNA clone CS0DK002YE20 of HeLa cells Cot 25-normalized of Homo sapiens (human)
AK024986.1	Homo sapiens cDNA: FLJ21333 fis, clone COL02535	A
BC005821.2	Homo sapiens phosphatase and tensin homolog, mRNA (cDNA clone MGC:11227 IMAGE:3937787), complete cds	PA
AK313581.1	Homo sapiens cDNA, FLJ94145, Homo sapiens phosphatase and tensin homolog (mutated in multipleadvanced cancers 1) (PTEN), mRNA
U92436.1	Human mutated in multiple advanced cancers protein (MMAC1) mRNA, complete cds	PA
U96180.1	Human protein tyrosine phosphatase (TEP1) mRNA, complete cds	PA
U93051.1	Human putative protein tyrosine phosphatase (PTEN) mRNA, complete cds	P

EST sequences (10 of 388) [Show all sequences]

AA954495.1	Clone IMAGE:1563063	mixed	3' read
AA977984.1	Clone IMAGE:1590220	kidney	3' read
AI016285.1	Clone IMAGE:1622293	embryonic tissue	3' read	A
AI089058.1	Clone IMAGE:1634656	mixed	3' read
AI090152.1	Clone IMAGE:1698079	uterus	3' read	A
AI125980.1	Clone IMAGE:1712660	uterus	3' read	A
AI214472.1	Clone IMAGE:1840413	mixed	3' read	P
AI222037.1	Clone IMAGE:1843443	mixed	3' read	P
AI223055.1	Clone IMAGE:1840501	mixed	3' read	P
CB139774.1	Clone L15CKK1-5-F11	liver	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria