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UGID:687630     UniGene Hs.472471     Homo sapiens (human)   CHMP4B
Chromatin modifying protein 4B (CHMP4B)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_083638.1 chromatin modifying protein 4B M. musculus 100.0 223
XP_001105255.1 PREDICTED: similar to Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (Vacuolar protein sorting 7-2) (SNF7-2) (hSnf7-2) (SNF7 homolog associated with Alix 1) (hVps32) M. mulatta 100.0 223
NP_789782.1 chromatin modifying protein 4B H. sapiens 100.0 223
NP_001121978.1 chromatin modifying protein 4B B. taurus 99.5 223
NP_001088290.1 hypothetical protein LOC495125 X. laevis 94.5 220
NP_956489.1 hypothetical protein LOC393164 D. rerio 92.7 219
NP_610462.3 shrub CG8055-PA D. melanogaster 70.2 225
NP_495337.1 related to yeast Vacuolar Protein Sorting factor family member (vps-32.1) C. elegans 69.2 220
NP_013125.1 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; Snf7p S. cerevisiae 46.5 228

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (4.7 pct) in cDNA library dbEST:7562, CI0089.
Note: Highly represented (1.9 pct) in cDNA library dbEST:2878, CT0201.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: intestine; brain; pancreas; placenta; mixed; uncharacterized tissue; uterus; kidney; lung; larynx; adrenal gland; lymph node; prostate; stomach; blood; mammary gland; eye; testis; embryonic tissue; cervix; skin; ovary; heart; ear; ascites; connective tissue; bladder; bone; bone marrow; mouth; thyroid; pharynx; nerve; ganglia; salivary gland; muscle; esophagus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q11.22
UniSTS entry: Chr 20 STS-AA029286
UniSTS entry: Chr 20 WI-21040
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_176812.3 Homo sapiens chromatin modifying protein 4B (CHMP4B), mRNA PA
AB100261.1 Homo sapiens Shax1 mRNA for Snf7 homologue associated with Alix 1, complete cds P
AY329085.1 Homo sapiens SNF7-2 mRNA, complete cds P
CR625458.1 full-length cDNA clone CS0DN005YJ08 of Adult brain of Homo sapiens (human) P
CR623996.1 full-length cDNA clone CS0DF023YP11 of Fetal brain of Homo sapiens (human) P
CR616273.1 full-length cDNA clone CS0DK007YD01 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR615678.1 full-length cDNA clone CS0DF007YB21 of Fetal brain of Homo sapiens (human) P
CR615467.1 full-length cDNA clone CS0DI068YJ02 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR611521.1 full-length cDNA clone CS0DI031YP10 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR610271.1 full-length cDNA clone CS0DJ015YG10 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR607577.1 full-length cDNA clone CS0DI007YL06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR601594.1 full-length cDNA clone CS0DI056YN20 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR594629.1 full-length cDNA clone CS0DB003YN21 of Neuroblastoma Cot 10-normalized of Homo sapiens (human)
CR592058.1 full-length cDNA clone CS0DI022YM21 of Placenta Cot 25-normalized of Homo sapiens (human)
AY726594.1 Homo sapiens clone MO-23 mRNA sequence P
BC033859.1 Homo sapiens chromatin modifying protein 4B, mRNA (cDNA clone MGC:45387 IMAGE:5173394), complete cds PA

EST sequences (10 of 393) [Show all sequences]

AA971764.1 Clone IMAGE:1583705 mixed 3' read A
AA989227.1 Clone IMAGE:1601866 lung 3' read A
AI057365.1 Clone IMAGE:1674586 mixed 3' read A
AI088555.1 Clone IMAGE:1696050 uterus 3' read A
AI090085.1 Clone IMAGE:1697058 uterus 3' read A
AI095652.1 Clone IMAGE:1697720 uterus 3' read A
AA907442.1 Clone IMAGE:1522320 lung 3' read A
CB069286.1 Clone IMAGE:6365042 pancreas 3' read P
CB069498.1 Clone IMAGE:6365042 pancreas 5' read P
AI149665.1 Clone IMAGE:1752201 testis 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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