Mitogen-activated protein kinase kinase 2, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.3 pct) in cDNA library dbEST:9000, CN0150.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; lung; mixed; skin; uncharacterized tissue; intestine; pancreas; prostate; mammary gland; ovary; embryonic tissue; eye; lymph node; testis; connective tissue; uterus; blood; placenta; muscle; heart; adrenal gland; spleen; ascites; salivary gland; stomach; lymph; bone; liver; tonsil; cervix; nerve; kidney; thymus; bladder; thyroid

NCBI

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Finding cDNAs

UGID:680786 UniGene Hs.465627 Homo sapiens (human) MAP2K2

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Mitogen-activated protein kinase kinase 2 (MAP2K2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001124224.1	mitogen-activated protein kinase kinase 1	B. taurus	91.8	392
NP_194710.1	ATMKK2 (MAP KINASE KINASE 2); MAP kinase kinase/ kinase	A. thaliana	47.5	305

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	19
	Map position:	19p13.3

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BX538081.1	Homo sapiens mRNA; cDNA DKFZp686L02273 (from clone DKFZp686L02273); complete cds	PA
CR617539.1	full-length cDNA clone CS0DC011YE15 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
CR615045.1	full-length cDNA clone CS0DC007YC05 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
CR609681.1	full-length cDNA clone CS0DC012YD19 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
BC000471.2	Homo sapiens mitogen-activated protein kinase kinase 2, mRNA (cDNA clone MGC:8600 IMAGE:2961198), complete cds	PA
NM_030662.3	Homo sapiens mitogen-activated protein kinase kinase 2 (MAP2K2), mRNA	A
BC018645.2	Homo sapiens mitogen-activated protein kinase kinase 2, mRNA (cDNA clone MGC:16530 IMAGE:4025987), complete cds	PA
L11285.1	Homosapiens ERK activator kinase (MEK2) mRNA	PA

EST sequences (10 of 628) [Show all sequences]

AA972316.1	Clone IMAGE:1582902	mixed	3' read
AA977389.1	Clone IMAGE:1589041	kidney	3' read
AA983895.1	Clone IMAGE:1581536	mixed	3' read	P
AA906317.1	Clone IMAGE:1506774	mixed	3' read
AA909456.1	Clone IMAGE:1523454	mixed	3' read
AI014597.1	Clone IMAGE:1607620	mammary gland	3' read
R18315.1	Clone IMAGE:31138	brain	5' read	P
AA948382.1	Clone IMAGE:1560278	intestine	3' read
AA948429.1	Clone IMAGE:1560319	intestine	3' read	P
AI033734.1	Clone IMAGE:1663497	skin	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria