Crystallin, alpha B, Homo sapiens

Expression Profile:

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Highly represented in several libraries

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

eye; brain; muscle; heart; mammary gland; placenta; skin; lung; kidney; stomach; spinal cord; intestine; uncharacterized tissue; adipose tissue; spleen; mixed; vascular; uterus; embryonic tissue; bone marrow; ear; bone; pancreas; umbilical cord; nerve; mouth; adrenal gland; larynx; testis; connective tissue; prostate; thyroid; liver; ovary; pharynx; pineal gland; esophagus; epididymis; peritoneum; pituitary gland; cervix; ganglia

NCBI

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Finding cDNAs

UGID:221154 UniGene Hs.408767 Homo sapiens (human) CRYAB

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Crystallin, alpha B (CRYAB)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001106498.1	PREDICTED: crystallin, alpha B	M. mulatta	100.0	174
XP_508752.2	PREDICTED: crystallin, alpha B	P. troglodytes	100.0	174
NP_001876.1	crystallin, alpha B	H. sapiens	100.0	174
NP_034094.1	crystallin, alpha B	M. musculus	99.4	174
NP_571232.1	crystallin, alpha B, a	D. rerio	70.2	167
NP_001086479.1	MGC83413 protein	X. laevis	68.5	167
NP_523827.1	lethal (2) essential for life CG4533-PA, isoform A	D. melanogaster	51.4	183

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11q22.3-q23.1
UniSTS entry:	Chr 11	D11S2244E
UniSTS entry:	Chr 11	RH17897
UniSTS entry:	Chr 11	SHGC-31520
UniSTS entry:	Chr 11	D11S3407
UniSTS entry:	Chr 11	CRYA2

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF007162.1	Homo sapiens unknown mRNA, complete cds	P
BT006770.1	Homo sapiens crystallin, alpha B mRNA, complete cds	P
NM_001885.1	Homo sapiens crystallin, alpha B (CRYAB), mRNA	P
M24906.1	Homo sapiens Rosenthal fiber protein (alpha-B-crystallin) mRNA, 3' end	P
BC007008.1	Homo sapiens crystallin, alpha B, mRNA (cDNA clone MGC:12326 IMAGE:3933748), complete cds	PA
AK314029.1	Homo sapiens cDNA, FLJ94689, Homo sapiens crystallin, alpha B (CRYAB), mRNA	P
AK295498.1	Homo sapiens cDNA FLJ57064 complete cds, highly similar to Alpha crystallin B chain (Alpha(B)-crystallin)	P
S45630.1	alpha B-crystallin=Rosenthal fiber component [human, glioma cell line, mRNA, 691 nt]	P

EST sequences (10 of 1030) [Show all sequences]

AI001188.1	Clone IMAGE:1637770	mammary gland	3' read	PA
AI003427.1	Clone IMAGE:1414847	spleen	3' read	PA
AI024887.1	Clone IMAGE:1631412	mammary gland	3' read
AI057452.1	Clone IMAGE:1653128	mixed	3' read	PA
R21164.1	Clone IMAGE:130255	placenta	5' read
R22781.1	Clone IMAGE:130255	placenta	3' read	A
AI126499.1	Clone IMAGE:1713144	uterus	3' read	PA
R23224.1	Clone IMAGE:131042	placenta	3' read	A
AI131175.1	Clone IMAGE:1709669	heart	3' read	PA
AI139361.1	Clone IMAGE:1710670	uterus	3' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria