NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Query Tips
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
dbEST
Trace Archive

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:189571     UniGene Hs.332706     Homo sapiens (human)   OPTN Order cDNA clone, Links
Optineurin (OPTN)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_068815.2 optineurin H. sapiens 100.0 576
XP_001139979.1 PREDICTED: optineurin isoform 4 P. troglodytes 99.8 576
NP_862896.1 optineurin M. musculus 84.9 583
NP_001088901.1 hypothetical protein LOC496250 X. laevis 50.0 516
NP_001093536.1 optineurin D. rerio 48.4 511

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (1.1 pct) in cDNA library dbEST:3133, CT0279.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; lung; testis; muscle; mammary gland; kidney; nerve; liver; placenta; uterus; eye; uncharacterized tissue; mixed; prostate; skin; bone marrow; amniotic fluid; mouth; spleen; ovary; parathyroid; blood; thymus; heart; bone; intestine; pituitary gland; connective tissue; pancreas; bladder; embryonic tissue; vascular; larynx; trachea; cervix; ear; thyroid; spinal cord; adrenal gland; adipose tissue; lymph node; esophagus; ascites; ganglia; umbilical cord; stomach; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10p13
UniSTS entry: Chr 10 D10S1295E
UniSTS entry: Chr 10 RH11306
UniSTS entry: Chr 10 RH70007
UniSTS entry: Chr 10 A006T03
UniSTS entry: Chr 10 SHGC-133063
UniSTS entry: Chr 12 SHGC-63482
UniSTS entry: Chr 10 D10S232E [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AF070533.1 Homo sapiens clone 24619 mRNA sequence A
AK122746.1 Homo sapiens cDNA FLJ16271 fis, clone NOVAR2002039, highly similar to Homo sapiens FIP2 alternatively translated mRNA P
CR614451.1 full-length cDNA clone CS0DI038YB01 of Placenta Cot 25-normalized of Homo sapiens (human)
CR603260.1 full-length cDNA clone CS0DI003YG24 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR601600.1 full-length cDNA clone CS0DC016YG04 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR597026.1 full-length cDNA clone CS0DL009YF13 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
NM_001008213.1 Homo sapiens optineurin (OPTN), transcript variant 4, mRNA P
NM_001008212.1 Homo sapiens optineurin (OPTN), transcript variant 3, mRNA P
NM_001008211.1 Homo sapiens optineurin (OPTN), transcript variant 1, mRNA P
NM_021980.4 Homo sapiens optineurin (OPTN), transcript variant 2, mRNA P
BC013876.2 Homo sapiens optineurin, mRNA (cDNA clone MGC:10510 IMAGE:3831267), complete cds PA
AK055403.1 Homo sapiens cDNA FLJ30841 fis, clone FEBRA2002508, highly similar to Optineurin P
AF420373.1 Homo sapiens optineurin isoform 3 (OPTN) mRNA, complete cds P
AF420372.1 Homo sapiens optineurin isoform 2 (OPTN) mRNA, complete cds P
AF420371.1 Homo sapiens optineurin isoform 1 (OPTN) mRNA, complete cds P
BC032762.1 Homo sapiens optineurin, mRNA (cDNA clone MGC:44991 IMAGE:3457195), complete cds PA
AK303715.1 Homo sapiens cDNA FLJ53267 complete cds, highly similar to Optineurin P
AF049614.1 Homo sapiens huntingtin interacting protein HYPL mRNA, partial cds P
AF061034.1 Homo sapiens FIP2 alternatively translated mRNA, complete cds PA

EST sequences (10 of 530) [Show all sequences]

AA987243.1 Clone IMAGE:1604253 lung 3' read
AI022578.1 Clone IMAGE:1649926 parathyroid 3' read
AA903792.1 Clone IMAGE:1517910 uncharacterized tissue 3' read
AI124677.1 Clone IMAGE:1539951 brain 3' read P
AI125565.1 Clone IMAGE:1736712 testis 3' read PA
AI168158.1 Clone IMAGE:1565688 mixed 3' read
AI191456.1 Clone IMAGE:1740699 lung 3' read
CB143416.1 Clone L16HLK3-12-H03 liver 5' read P
CB143587.1 Clone L16HLK3-27-D01 liver 5' read
CB155956.1 Clone L17N670205n1-1-F09 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help