Chromosome 10 open reading frame 2, Homo sapiens

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UGID:134514 UniGene Hs.22678 Homo sapiens (human) C10orf2

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Chromosome 10 open reading frame 2 (C10orf2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_068602.2	twinkle	H. sapiens	100.0	683
NP_722491.2	twinkle	M. musculus	91.2	684
NP_001084540.1	hypothetical protein LOC414487	X. laevis	74.3	677
NP_609318.1	CG5924 CG5924-PA	D. melanogaster	53.4	586

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	Expression Profile:	View expression levels using UniGene's EST ProfileViewer [Show more entries with profiles like this]
	GEO profiles:	Gene expression profiles in the NCBI Gene Expression Omnibus database
	cDNA Sources:	lymph; brain; skin; eye; liver; testis; embryonic tissue; mammary gland; uterus; kidney; uncharacterized tissue; lymph node; ovary; intestine; lung; mixed; muscle; cervix; placenta; connective tissue; pancreas; bone; esophagus; pharynx; mouth; blood; adrenal gland; stomach; ascites; thyroid; prostate; spleen; heart

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	10
Map position:	10q23.3-q24.3
UniSTS entry:	Chr 10	SHGC-32265

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BX640829.1	Homo sapiens mRNA; cDNA DKFZp686O01205 (from clone DKFZp686O01205)	PA
CR626239.1	full-length cDNA clone CS0DK002YB08 of HeLa cells Cot 25-normalized of Homo sapiens (human)	P
CR593649.1	full-length cDNA clone CS0DD005YE06 of Neuroblastoma Cot 50-normalized of Homo sapiens (human)	P
AK022959.1	Homo sapiens cDNA FLJ12897 fis, clone NT2RP2004207	P
AK025485.1	Homo sapiens cDNA: FLJ21832 fis, clone HEP01571	PA
NM_021830.3	Homo sapiens chromosome 10 open reading frame 2 (C10orf2), mRNA	PA
AF292005.1	Homo sapiens truncated putative T7-like mitochondrial DNA helicase (C10orf2) mRNA, complete cds; nuclear gene for mitochondrial product; alternatively spliced	P
AF292004.1	Homo sapiens putative T7-like mitochondrial DNA helicase (C10orf2) mRNA, complete cds; nuclear gene for mitochondrial product; alternatively spliced	P
AK308098.1	Homo sapiens cDNA, FLJ98046	P
BC033762.1	Homo sapiens chromosome 10 open reading frame 2, mRNA (cDNA clone MGC:44998 IMAGE:3854007), complete cds	PA
AK297068.1	Homo sapiens cDNA FLJ50799 complete cds, highly similar to Twinkle protein, mitochondrial precursor (EC 3.6.1.-)	P
BC013349.2	Homo sapiens chromosome 10 open reading frame 2, mRNA (cDNA clone IMAGE:3954451), partial cds	PA

EST sequences (10 of 263) [Show all sequences]

AA991666.1	Clone IMAGE:1621998	embryonic tissue	3' read
R19418.1	Clone IMAGE:33362	brain	5' read	P
AI205573.1	Clone IMAGE:1836690	testis	3' read
CB159220.1	Clone L18POOL1n1-34-A02	liver	5' read	P
CB112401.1	Clone L6ChoCK0-3-A07	liver	5' read	P
AI313004.1	Clone IMAGE:2050877	brain	3' read
AI334204.1	Clone IMAGE:1932036	mixed	3' read
AI343124.1	Clone IMAGE:2052614	lung	3' read
AI349969.1	Clone IMAGE:2052067	lung	3' read
AI380281.1	Clone IMAGE:2107437	uncharacterized tissue	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria