Mitogen-activated protein kinase kinase 1, Homo sapiens

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UGID:151824 UniGene Hs.145442 Homo sapiens (human) MAP2K1

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Mitogen-activated protein kinase kinase 1 (MAP2K1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001124224.1	mitogen-activated protein kinase kinase 1	B. taurus	100.0	392

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	Expression Profile:	View expression levels using UniGene's EST ProfileViewer [Show more entries with profiles like this]
	GEO profiles:	Gene expression profiles in the NCBI Gene Expression Omnibus database
	cDNA Sources:	brain; prostate; embryonic tissue; lung; placenta; uterus; uncharacterized tissue; kidney; intestine; mixed; bone marrow; pituitary gland; testis; adrenal gland; ovary; stomach; ear; mouth; thyroid; blood; eye; thymus; mammary gland; skin; heart; bone; larynx; salivary gland; spleen; nerve; umbilical cord; lymph node; connective tissue; liver; pancreas; lymph; vascular; muscle; parathyroid; cervix; trachea; pineal gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	15
	Map position:	15q22.1-q22.33

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

L05624.1	Homo sapiens MAP kinase kinase mRNA, complete cds	P
NM_002755.3	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA	A
CR621481.1	full-length cDNA clone CL0BB019ZB06 of Neuroblastoma of Homo sapiens (human)	P
CR604502.1	full-length cDNA clone CS0DL011YC02 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human)
BC139729.1	Homo sapiens mitogen-activated protein kinase kinase 1, mRNA (cDNA clone MGC:133320 IMAGE:40053655), complete cds
AK291500.1	Homo sapiens cDNA FLJ76051 complete cds, highly similar to Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA
AK312356.1	Homo sapiens cDNA, FLJ92675
BC137459.1	Homo sapiens mitogen-activated protein kinase kinase 1, mRNA (cDNA clone MGC:169082 IMAGE:9021459), complete cds
AK294322.1	Homo sapiens cDNA FLJ58770 complete cds, highly similar to Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2)
L11284.1	Homosapiens ERK activator kinase (MEK1) mRNA	PA

EST sequences (10 of 265) [Show all sequences]

AA955037.1	Clone IMAGE:1591365	kidney	3' read
AA983277.1	Clone IMAGE:1592504	kidney	3' read	A
AI022864.1	Clone IMAGE:1650638	parathyroid	3' read	A
R19938.1	Clone IMAGE:33826	brain	5' read
AI091721.1	Clone IMAGE:1651143	mixed	3' read	A
AI129844.1	Clone IMAGE:1711568	uterus	3' read	A
AI168089.1	Clone IMAGE:1682511	skin	3' read
BX100605.1	Clone IMAGp998N055847_;_IMAGE:2356036	vascular
CB157458.1	Clone L17N670205n1-9-H05	liver	5' read
CB164273.1	Clone L17N670205n1-29-F10	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria