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UGID:145319     UniGene Hs.118681     Homo sapiens (human)   ERBB3
V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_001973.2 erbB-3 isoform 1 precursor H. sapiens 100.0 1341
XP_136682.7 PREDICTED: v-erb-a erythroblastic leukemia viral oncogene homolog 4 isoform 2 M. musculus 63.8 1153
NP_001005320.1 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a D. rerio 62.0 1300

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; mammary gland; mouth; skin; trachea; prostate; placenta; lung; kidney; liver; connective tissue; eye; embryonic tissue; uterus; amniotic fluid; uncharacterized tissue; spinal cord; ear; stomach; mixed; ovary; cervix; adrenal gland; ascites; muscle; esophagus; heart; nerve; pancreas; testis; larynx; thyroid; bladder; ganglia; vascular; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13
UniSTS entry: Chr 12 WI-16415
UniSTS entry: Chr 12 RK1196_1197
UniSTS entry: Chr 12 SHGC-35265
UniSTS entry: Chr 12 STS-M34309
UniSTS entry: Chr 12 D12S1388E
UniSTS entry: Chr 12 (n/a)
UniSTS entry: G15952
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

U88357.1 Homo sapiens clone R1 ErbB-3 R1 (c-erbB-3) mRNA, partial cds A
U88358.1 Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial cds A
U88359.1 Homo sapiens clone R31 ErbB-3 R31 (c-erbB-3) mRNA, partial cds PA
U88360.1 Homo sapiens clone R35 ErbB-3 R35 (c-erbB-3) mRNA, partial cds PA
M34309.1 Human epidermal growth factor receptor (HER3) mRNA, complete cds
BT007226.1 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) mRNA, complete cds P
AK125028.1 Homo sapiens cDNA FLJ43038 fis, clone BRTHA3002955, highly similar to Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1)
AK124710.1 Homo sapiens cDNA FLJ42720 fis, clone BRAMY4000095, highly similar to Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1)
NM_001982.2 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3), transcript variant 1, mRNA P
CR621450.1 full-length cDNA clone CS0DI087YP06 of Placenta Cot 25-normalized of Homo sapiens (human) P
BC082992.1 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), mRNA (cDNA clone MGC:88033 IMAGE:6147464), complete cds PA
NM_001005915.1 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3), transcript variant s, mRNA P
BC002706.2 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), mRNA (cDNA clone IMAGE:3629646), complete cds PA
AK291681.1 Homo sapiens cDNA FLJ76884 complete cds, highly similar to Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3), transcript variant 1, mRNA P
AK294719.1 Homo sapiens cDNA FLJ59207 complete cds, highly similar to Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) P
AK300909.1 Homo sapiens cDNA FLJ53210 complete cds, highly similar to Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) P
AK295650.1 Homo sapiens cDNA FLJ55330 complete cds, highly similar to Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) P
AF086028.1 Homo sapiens full length insert cDNA clone YW24E06 A
S61953.1 c-erbB3=receptor tyrosine kinase {alternatively spliced} [human, gastric cancer cell line MNK45, mRNA, 1042 nt] PA
BC041579.1 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), mRNA (cDNA clone IMAGE:4645144) A
M29366.1 Human epidermal growth factor receptor (ERBB3) mRNA, complete cds P

EST sequences (10 of 641) [Show all sequences]

AA975597.1 Clone IMAGE:1588913 kidney 3' read
AA976312.1 Clone IMAGE:1589552 kidney 3' read A
AI000926.1 Clone IMAGE:1613017 uncharacterized tissue 3' read A
R19834.1 Clone IMAGE:34038 brain 5' read
AI078622.1 Clone IMAGE:1659817 embryonic tissue 3' read
CB046349.1 Clone IMAGE:3252730 kidney 3' read A
CB046350.1 Clone IMAGE:3252730 kidney 5' read A
AI147107.1 Clone IMAGE:1509694 mixed 3' read
BX098146.1 Clone IMAGp998A21118_;_IMAGE:123164 mixed A
CB160706.1 Clone L18POOL1n1-22-H07 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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