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The following information (Health Effects, Handling/Disposal, and Ingredients) is taken from the product label and/or the Material Safety Data Sheet (MSDS) prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS.
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Health Effects
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From MSDS
HAZARDS IDENTIFICATION
Primary Route(s) of Entry: Inhalation, Skin absorption, Skin contact.
Potential Health Effects
Eye: Can cause eye irritation.
Skin: May cause mild skin irritation. Prolonged or repeated contact may dry and crack the skin. Although rare, skin contact with ethylene glycol may cause allergic skin reaction (delayed skin rash which may be followed by blistering, scaling and other skin effects). Passage through the skin may add to toxic effects from breathing or swallowing.
Swallowing: Swallowing this material may be harmful.
Inhalation Breathing of vapor or mist is possible. Breathing small amounts of this material during normal handling is not likely to cause harmful effects. Breathing large amounts may be harmful.
Symptoms of Exposure: stomach or intestinal upset (nausea, vomiting, diarrhea), irritation (nose, throat, airways), central nervous system excitation (giddiness, liveliness, light-headed feeling) followed by central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness) and other central nervous system effects, involuntary eye movement, visual impairment (including blindness), and death.
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From MSDS
No information provided.
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From MSDS
No data.
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From MSDS
Eyes: If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
Skin: Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
Swallowing: Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Inhalation: If symptoms develop, immediately move individual away from exposure and into fresh air. Seek immediate medical attention; keep person warm and quiet. If person is not breathing, begin artificial respiration. If breathing is difficult, administer oxygen.
This product contains methanol which can cause intoxication and central nervous system depression. Methanol is metabolized to formic acid and formaldehyde. These metabolites can cause metabolic acidosis, visual disturbances and blindness. Since metabolism is required for these toxic symptoms, their onset may be delayed from 6 to 30 hours following ingestion. Ethanol competes for the same metabolic pathway and has been used to prevent methanol metabolism. Ethanol administration is indicated in symptomatic patients or at blood methanol concentrations above 20 ug/dl. Methanol is effectively removed by hemodialysis. This product contains ethylene glycol. Ethanol decreases the metabolism of ethylene glycol to toxic metabolites. Ethanol should be administered as soon as possible in cases of severe poisoning since the elimination half-life of ethylene glycol is 3 hours. If medical care will be delayed several hours, give the patient three to four 1-ounce oral "shots" of 86-proof or higher whiskey before or during transport to the hospital. Fomepizole (4-methylpyrazole) is an effective antagonist of alcohol dehydrogenase, and as such, may be used as an antidote in the treatment of ethylene glycol poisoning. Hemodialysis effectively removes ethylene glycol and its metabolites from the body. Effects of acute ethylene glycol poisoning appear in three fairly distinct stages. The initial stage occurs shortly after exposure, lasts 6-12 hours, and is characterized by central nervous system effects (transient exhilaration, nausea, vomiting, and in severe cases, coma, convulsions, and possible death. The second stage lasts from 12-36 hours after exposure and is initiated by the onset of coma. This phase is characterized by tachypnea, tachycardia, mild hypotension, cyanosis, and in severe cases, pulmonary edema, bronchopneumonia, cardiac enlargement, and congestive failure. The final stage occurs 24-72 post-exposure and is characterized by renal failure ranging from a mild increase in blood urea nitrogen and creatinine followed by recovery to complete anuria with acute tubular necrosis that can lead to death. Oxaluria is found in most cases. The most significant laboratory finding in ethylene glycol intoxication is severe metabolic acidosis. Preexisting disorders of the following organs ( or organ systems) may be aggravated by exposure to this material: skin.
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0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe; N = No information provided by manufacturer; * = Chronic Health Hazard |
2002-01-14 |
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Handling/Disposal
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From MSDS
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.
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From MSDS
Dispose of in accordance with all applicable local, state and federal regulations.
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Ingredients from MSDS/Label
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