Tell CCR
"Tell CCR" about newly accepted/in press papers prior to online and print publication. Please include a copy of the manuscript in your e-mail to tellccr@mail.nih.gov
Questions may be directed to Donna Kerrigan
NOTE: Questions may be directed to
Donna Kerrigan
Prostate Cancer Stem-Like Cells
Prostate cancer is the third leading cause of cancer-related death among men, killing an estimated 27,000 men each year in the United States. Men with advancedprostate cancer often become resis-tant to conventional therapies. Many researchers speculate... read more...
Proteasome Inhibitors: A Worthy Partner to Boost Cancer Immunotherapy?
For a number of years, researchers have been frustrated by their inability to harness patients’ immune systems to stem tumor growth. However, recent preclinical data involving the use of immunother-apy in combination with proteasome inhibition... read more...
Microenvironment May Drive Follicular Lymphoma
Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma and rep-resents 20 percent of all lymphomas diagnosed in adults. Although it is a slow growing cancer, FL is largely incurable — half of all patients diag-nosed with the disease die within... read more...
Efficient DNA Repair: A Cell’s Fountain of Youth?
Given the central importance of the genome to a cell’s function, it is not surprising that there are a number of proteins devoted to sensing and repairing DNA damage. But what happens when these repair proteins do not work properly? Cancer is one possible outcome, and a growing body of evidence also indicates that the cellular response to... read more...
Thrombospondin 1 Wages a Double Hit Against Cancer
Cancer is the result of a complex series of molecular steps that promote uncontrolled growth and erode the body’s ability to fight the resulting tumor. Generating a more complete picture of these molecular events should help identify strategies to prevent and treat the... read more...
Exposing Cancer Cells’ Secret Aides to Spread Disease to Distant Sites
Researchers are shedding new light on the way cancer spreads from the primary organ to distant sites in the body, a process called metastasis. The assault of metastatic tumors on vital organs too frequently results in death, and until recently, little was known... read more...
Combined Therapy Conquers Resistant Tumors: Bortezomib and TRAIL
The principal strategy in the battle against cancer is simple: kill as many tumor cells as possible while sparing healthy cells. Unfortunately, traditional treatments, such as chemotherapy and radiation, have... read more...
The Cell’s Sophisticated Army to Defend Against Assaults on DNA
The maintenance of genome integrity and function is essen-tial for the survival of cells and organisms. Any damage to our genetic material must be immediately sensed and repaired... read more...
