| Agent Name |
Ethylene thiourea |
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| CAS Number |
96-45-7 |
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| Formula |
C3-H6-N2-S |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
1,3-Ethylene-2-thiourea; 1,3-Ethylenethiourea; 2-Imidazolidinethione; 2-Imidazoline-2-thiol; 2-Mercapto-2-imidazoline; 2-Mercaptoimidazoline; 2-Merkaptoimidazolin [Czech]; 2-Thiol-dihydroglyoxaline; 4,5-Dihydro-2-mercaptoimidazole; 4,5-Dihydroimidazole-2(3H)-thione; Akrochem etu-22; Aperochem ETU-22; ETU; Ethylene thiourea; Ethylene thiouree [French]; Ethylenethiourea; Imidazole-2(3H)-thione, 4,5-dihydro-; Imidazolidinethione; Imidazoline, 2-mercapto-; Imidazoline-2(3H)-thione; Imidazoline-2-thiol; Mercaptoimidazoline; Mercazin I; N,N'-Ethylenethiourea; NA-22; NA-22-D; Nocceler 22; Pennac CRA; Rhenogran etu; Rhodanin S 62; Robac 22; Rodanin S-62 [Czech]; Sanceller 22; Sodium-22 neoprene accelerator; Soxinol 22; Tetrahydro-2H-imidazole-2-thione; Thiourea, N,N'-(1,2-ethanediyl)-; Urea, 1,3-ethylene-2-thio-; Vulkacit NPV/C; Vulkacit npv/C2; Warecure C; l'Ethylene thiouree [French]; [ChemIDplus] |
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| Category |
Rubber Additives |
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| Description |
White to pale-green, crystalline solid with a faint, amine odor. [Note: Used as an accelerator in the curing of polychloroprene & other elastomers.]; [NIOSH] |
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| Sources/Uses |
The alkylthioureas are used as rubber accelerators; they are also used in insoles, adhesives, wet suits, detergents, plastics, and textiles. [Marks, p. 240] |
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| Comments |
Potential skin sensitizer; [Marks, p. 240] [Allergic contact dermatitis from ethylene thiourea. Bruze M, Fregert S. Contact Dermatitis 1983;3:208-12] Ethylenethiourea is a common contaminant of ethylene bisdithiocarbamates (Ferbam, Mancozeb, Maneb, Metiram, Nabam, Thiram, Vapam, Ziram, and Zineb). It causes birth defects in high-dose reproductive studies of experimental animals. [Frazier, p. 230-2] May have effects on the thyroid gland and liver; [ICSC] An eye irritant; [CAMEO] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
2.02 x 10 -06 mm Hg |
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| Explanatory Notes |
NIOSH REL = lowest feasible concentration (carcinogen)--use in encapsulated form; Flash point = 486 deg F; |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Reproductive Toxin |
Yes |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ETHYLENE THIOUREA
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