Part 1. Introduction to Clinical Medicine |
| Chapter 1 | The Practice of Medicine |
| Chapter 2 | Global Issues in Medicine |
| Chapter 3 | Decision-Making in Clinical Medicine |
| Chapter 4 | Screening and Prevention of Disease |
| Chapter 5 | Principles of Clinical Pharmacology |
| Chapter 6 | Women's Health |
| Chapter 7 | Medical Disorders during Pregnancy |
| Chapter 8 | Medical Evaluation of the Surgical Patient |
| Chapter 9 | Geriatric Medicine |
| Chapter 10 | Complementary and Alternative Medicine
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| Chapter 11 | Palliative and End-of-Life Care
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| Chapter e1 | The Safety and Quality of Health Care |
| Chapter e2 | Economic Considerations in the Practice of Medicine |
| Chapter e3 | Racial and Ethnic Disparities in Health Care |
| Chapter e4 | Ethical Issues in Clinical Medicine |
Part 2. Cardinal Manifestations and Presentation of Diseases |
Section 1. Pain |
| Chapter 12 | Pain: Pathophysiology and Management |
| Chapter 13 | Chest Discomfort |
| Chapter 14 | Abdominal Pain |
| Chapter 15 | Headache
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| Chapter 16 | Back and Neck Pain
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Section 2. Alterations in Body Temperature |
| Chapter 17 | Fever and Hyperthermia |
| Chapter 18 | Fever and Rash |
| Chapter e5 | Atlas of Rashes Associated with Fever |
| Chapter 19 | Fever of Unknown Origin |
| Chapter 20 | Hypothermia and Frostbite |
Section 3. Nervous System Dysfunction |
| Chapter 21 | Syncope
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| Chapter 22 | Dizziness and Vertigo
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| Chapter 23 | Weakness and Paralysis |
| Chapter 24 | Gait and Balance Disorders |
| Chapter 25 | Numbness, Tingling, and Sensory Loss |
| Chapter 26 | Confusion and Delirium |
| Chapter e6 | Memory Loss |
| Chapter 27 | Aphasia, Memory Loss, and Other Focal Cerebral Disorders |
| Chapter 28 | Sleep Disorders |
Section 4. Disorders of Eyes, Ears, Nose, and Throat |
| Chapter 29 | Disorders of the Eye |
| Chapter 30 | Disorders of Smell, Taste, and Hearing |
| Chapter 31 | Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections
Latest Update: |
| Chapter 32 | Oral Manifestations of Disease |
| Chapter e7 | Atlas of Oral Manifestations of Disease |
Section 5. Alterations in Circulatory and Respiratory Functions |
| Chapter 33 | Dyspnea and Pulmonary Edema |
| Chapter 34 | Cough and Hemoptysis |
| Chapter 35 | Hypoxia and Cyanosis |
| Chapter 36 | Edema |
| Chapter e8 | Approach to the Patient with a Heart Murmur |
| Chapter 37 | Palpitations |
Section 6. Alterations in Gastrointestinal Function |
| Chapter 38 | Dysphagia |
| Chapter 39 | Nausea, Vomiting, and Indigestion |
| Chapter 40 | Diarrhea and Constipation
Latest Update: |
| Chapter 41 | Weight Loss |
| Chapter 42 | Gastrointestinal Bleeding |
| Chapter 43 | Jaundice |
| Chapter 44 | Abdominal Swelling and Ascites |
Section 7. Alterations in Renal and Urinary Tract Function |
| Chapter 45 | Azotemia and Urinary Abnormalities |
| Chapter e9 | Atlas of Urinary Sediments and Renal Biopsies |
| Chapter 46 | Fluid and Electrolyte Disturbances |
| Chapter 47 | Hypercalcemia and Hypocalcemia |
| Chapter 48 | Acidosis and Alkalosis |
Section 8. Alterations in Sexual Function and Reproduction |
| Chapter 49 | Sexual Dysfunction |
| Chapter 50 | Hirsutism and Virilization |
| Chapter 51 | Menstrual Disorders and Pelvic Pain |
Section 9. Alterations in the Skin |
| Chapter 52 | Approach to the Patient with a Skin Disorder |
| Chapter 53 | Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders |
| Chapter 54 | Skin Manifestations of Internal Disease |
| Chapter 55 | Immunologically Mediated Skin Diseases |
| Chapter 56 | Cutaneous Drug Reactions |
| Chapter 57 | Photosensitivity and Other Reactions to Light |
| Chapter e10 | Atlas of Skin Manifestations of Internal Disease |
Section 10. Hematologic Alterations |
| Chapter 58 | Anemia and Polycythemia |
| Chapter 59 | Bleeding and Thrombosis |
| Chapter 60 | Enlargement of Lymph Nodes and Spleen |
| Chapter 61 | Disorders of Granulocytes and Monocytes |
| Chapter e11 | Atlas of Hematology and Analysis of Peripheral Blood Smears |
Part 3. Genetics and Disease |
| Chapter 62 | Principles of Human Genetics |
| Chapter 63 | Chromosome Disorders |
| Chapter 64 | The Practice of Genetics in Clinical Medicine |
| Chapter 65 | Gene Therapy in Clinical Medicine
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Part 4. Regenerative Medicine |
| Chapter 66 | Stem Cell Biology |
| Chapter 67 | Applications of Stem Cell Biology in Clinical Medicine |
| Chapter 68 | Hematopoietic Stem Cells |
| Chapter 69 | Tissue Engineering |
Part 5. Nutrition |
| Chapter 70 | Nutritional Requirements and Dietary Assessment |
| Chapter 71 | Vitamin and Trace Mineral Deficiency and Excess |
| Chapter 72 | Malnutrition and Nutritional Assessment |
| Chapter 73 | Enteral and Parenteral Nutrition Therapy |
| Chapter 74 | Biology of Obesity |
| Chapter 75 | Evaluation and Management of Obesity
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| Chapter 76 | Eating Disorders |
Part 6. Oncology and Hematology |
Section 1. Neoplastic Disorders |
| Chapter 77 | Approach to the Patient with Cancer
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| Chapter 78 | Prevention and Early Detection of Cancer |
| Chapter 79 | Cancer Genetics |
| Chapter 80 | Cancer Cell Biology and Angiogenesis
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| Chapter 81 | Principles of Cancer Treatment |
| Chapter 82 | Infections in Patients with Cancer |
| Chapter 83 | Cancer of the Skin |
| Chapter 84 | Head and Neck Cancer
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| Chapter 85 | Neoplasms of the Lung |
| Chapter 86 | Breast Cancer
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| Chapter 87 | Gastrointestinal Tract Cancer
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| Chapter 88 | Tumors of the Liver and Biliary Tree
Latest Update: |
| Chapter 89 | Pancreatic Cancer |
| Chapter 90 | Bladder and Renal Cell Carcinomas |
| Chapter 91 | Benign and Malignant Diseases of the Prostate
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| Chapter 92 | Testicular Cancer
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| Chapter 93 | Gynecologic Malignancies |
| Chapter 94 | Soft Tissue and Bone Sarcomas and Bone Metastases |
| Chapter 95 | Carcinoma of Unknown Primary |
| Chapter 96 | Paraneoplastic Syndromes: Endocrinologic/Hematologic |
| Chapter 97 | Paraneoplastic Neurologic Syndromes |
| Chapter e12 | Thymoma |
| Chapter e13 | Late Consequences of Cancer and Its Treatment |
Section 2. Hematopoietic Disorders |
| Chapter 98 | Iron Deficiency and Other Hypoproliferative Anemias |
| Chapter 99 | Disorders of Hemoglobin
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| Chapter 100 | Megaloblastic Anemias |
| Chapter 101 | Hemolytic Anemias and Anemia Due to Acute Blood Loss |
| Chapter 102 | Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes |
| Chapter 103 | Polycythemia Vera and Other Myeloproliferative Diseases |
| Chapter 104 | Acute and Chronic Myeloid Leukemia |
| Chapter 105 | Malignancies of Lymphoid Cells |
| Chapter 106 | Plasma Cell Disorders |
| Chapter 107 | Transfusion Biology and Therapy
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| Chapter 108 | Hematopoietic Cell Transplantation |
Section 3. Disorders of Hemostasis |
| Chapter 109 | Disorders of Platelets and Vessel Wall |
| Chapter 110 | Coagulation Disorders |
| Chapter 111 | Venous Thrombosis |
| Chapter 112 | Antiplatelet, Anticoagulant, and Fibrinolytic Drugs
Latest Update: |
Part 7. Infectious Diseases |
Section 1. Basic Considerations in Infectious Diseases |
| Chapter 113 | Introduction to Infectious Diseases: HostPathogen Interactions |
| Chapter 114 | Molecular Mechanisms of Microbial Pathogenesis |
| Chapter 115 | Approach to the Acutely Ill Infected Febrile Patient |
| Chapter 116 | Immunization Principles and Vaccine Use
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| Chapter 117 | Health Advice for International Travel
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| Chapter e14 | Laboratory Diagnosis of Infectious Diseases |
Section 2. Clinical Syndromes: Community-Acquired Infections |
| Chapter 118 | Infective Endocarditis
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| Chapter 119 | Infections of the Skin, Muscle, and Soft Tissues |
| Chapter 120 | Osteomyelitis |
| Chapter 121 | Intraabdominal Infections and Abscesses
Latest Update: |
| Chapter 122 | Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning |
| Chapter 123 | Clostridium difficileAssociated Disease, Including Pseudomembranous Colitis
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| Chapter 124 | Sexually Transmitted Infections: Overview and Clinical Approach |
| Chapter e15 | Infectious Complications of Burns and Bites |
Section 3. Clinical Syndromes: Health Care–Associated Infections |
| Chapter 125 | Health CareAssociated Infections
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| Chapter 126 | Infections in Transplant Recipients |
Section 4. Approach to Therapy for Bacterial Diseases |
| Chapter 127 | Treatment and Prophylaxis of Bacterial Infections |
Section 5. Diseases Caused by Gram-Positive Bacteria |
| Chapter 128 | Pneumococcal Infections
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| Chapter 129 | Staphylococcal Infections
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| Chapter 130 | Streptococcal and Enterococcal Infections
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| Chapter 131 | Diphtheria and Other Infections Caused by Corynebacteria and Related Species |
| Chapter 132 | Infections Caused by Listeria monocytogenes |
| Chapter 133 | Tetanus |
| Chapter 134 | Botulism |
| Chapter 135 | Gas Gangrene and Other Clostridial Infections |
Section 6. Diseases Caused by Gram-Negative Bacteria |
| Chapter 136 | Meningococcal Infections |
| Chapter 137 | Gonococcal Infections |
| Chapter 138 | Moraxella Infections |
| Chapter 139 | Haemophilus Infections |
| Chapter 140 | Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria |
| Chapter 141 | Legionella Infection |
| Chapter 142 | Pertussis and Other Bordetella Infections |
| Chapter 143 | Diseases Caused by Gram-Negative Enteric Bacilli |
| Chapter 144 | Helicobacter pylori Infections
Latest Update: |
| Chapter 145 | Infections Due to Pseudomonas Species and Related Organisms |
| Chapter 146 | Salmonellosis |
| Chapter 147 | Shigellosis |
| Chapter 148 | Infections Due to Campylobacter and Related Species |
| Chapter 149 | Cholera and Other Vibrioses |
| Chapter 150 | Brucellosis |
| Chapter 151 | Tularemia |
| Chapter 152 | Plague and Other Yersinia Infections |
| Chapter 153 | Bartonella Infections, Including Cat-Scratch Disease |
| Chapter 154 | Donovanosis |
Section 7. Miscellaneous Bacterial Infections |
| Chapter 155 | Nocardiosis |
| Chapter 156 | Actinomycosis |
| Chapter 157 | Infections Due to Mixed Anaerobic Organisms |
Section 8. Mycobacterial Diseases |
| Chapter 158 | Tuberculosis
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| Chapter 159 | Leprosy (Hansen's Disease) |
| Chapter 160 | Nontuberculous Mycobacteria |
| Chapter 161 | Antimycobacterial Agents
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Section 9. Spirochetal Diseases |
| Chapter 162 | Syphilis
Latest Update: |
| Chapter 163 | Endemic Treponematoses |
| Chapter 164 | Leptospirosis |
| Chapter 165 | Relapsing Fever |
| Chapter 166 | Lyme Borreliosis |
Section 10. Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae |
| Chapter 167 | Rickettsial Diseases |
| Chapter 168 | Infections Due to Mycoplasmas |
| Chapter 169 | Chlamydial Infections |
Section 11. Viral Diseases: General Considerations |
| Chapter 170 | Medical Virology |
| Chapter 171 | Antiviral Chemotherapy, Excluding Antiretroviral Drugs |
Section 12. Infections Due to DNA Viruses |
| Chapter 172 | Herpes Simplex Viruses |
| Chapter 173 | Varicella-Zoster Virus Infections
Latest Update: |
| Chapter 174 | Epstein-Barr Virus Infections, Including Infectious Mononucleosis |
| Chapter 175 | Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8 |
| Chapter 176 | Molluscum Contagiosum, Monkeypox, and Other Poxviruses, Excluding Smallpox Virus |
| Chapter 177 | Parvovirus Infections |
| Chapter 178 | Human Papillomavirus Infections
Latest Update: |
Section 13. Infections Due to DNA and RNA Respiratory Viruses |
| Chapter 179 | Common Viral Respiratory Infections and Severe Acute Respiratory Syndrome (SARS) |
| Chapter 180 | Influenza
Latest Update: |
Section 14. Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses |
| Chapter 181 | The Human Retroviruses |
| Chapter 182 | Human Immunodeficiency Virus Disease: AIDS and Related Disorders
Latest Update: |
Section 15. Infections Due to RNA Viruses |
| Chapter 183 | Viral Gastroenteritis |
| Chapter 184 | Enteroviruses and Reoviruses |
| Chapter 185 | Measles (Rubeola) |
| Chapter 186 | Rubella (German Measles) |
| Chapter 187 | Mumps
Latest Update: |
| Chapter 188 | Rabies and Other Rhabdovirus Infections |
| Chapter 189 | Infections Caused by Arthropod- and Rodent-Borne Viruses |
| Chapter 190 | Ebola and Marburg Viruses |
Section 16. Fungal and Algal Infections |
| Chapter 191 | Diagnosis and Treatment of Fungal Infections
Latest Update: |
| Chapter 192 | Histoplasmosis |
| Chapter 193 | Coccidioidomycosis |
| Chapter 194 | Blastomycosis |
| Chapter 195 | Cryptococcosis |
| Chapter 196 | Candidiasis
Latest Update: |
| Chapter 197 | Aspergillosis |
| Chapter 198 | Mucormycosis |
| Chapter 199 | Miscellaneous Mycoses and Algal Infections |
| Chapter 200 | Pneumocystis Infection |
Section 17. Protozoal and Helminthic Infections: General Considerations |
| Chapter e16 | Laboratory Diagnosis of Parasitic Infections |
| Chapter 201 | Agents Used to Treat Parasitic Infections |
| Chapter e17 | Pharmacology of Agents Used to Treat Parasitic Infections |
Section 18. Protozoal Infections |
| Chapter 202 | Amebiasis and Infection with Free-Living Amebas |
| Chapter 203 | Malaria |
| Chapter 204 | Babesiosis |
| Chapter e18 | Atlas of Blood Smears of Malaria and Babesiosis |
| Chapter 205 | Leishmaniasis
Latest Update: |
| Chapter 206 | Trypanosomiasis |
| Chapter 207 | Toxoplasma Infections |
| Chapter 208 | Protozoal Intestinal Infections and Trichomoniasis |
Section 19. Helminthic Infections |
| Chapter 209 | Trichinella and Other Tissue Nematodes |
| Chapter 210 | Intestinal Nematodes |
| Chapter 211 | Filarial and Related Infections |
| Chapter 212 | Schistosomiasis and Other Trematode Infections |
| Chapter 213 | Cestodes |
Part 8. Bioterrorism and Clinical Medicine |
| Chapter 214 | Microbial Bioterrorism |
| Chapter 215 | Chemical Bioterrorism |
| Chapter 216 | Radiation Bioterrorism |
Part 9. Disorders of the Cardiovascular System |
Section 1. Introduction to Cardiovascular Disorders |
| Chapter 217 | Basic Biology of the Cardiovascular System |
| Chapter 218 | Epidemiology of Cardiovascular Disease |
| Chapter 219 | Approach to the Patient with Possible Cardiovascular Disease |
Section 2. Diagnosis of Cardiovascular Disorders |
| Chapter 220 | Physical Examination of the Cardiovascular System |
| Chapter 221 | Electrocardiography |
| Chapter e19 | Atlas of Electrocardiography |
| Chapter 222 | Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and MRI/CT Imaging |
| Chapter e20 | Atlas of Noninvasive Cardiac Imaging |
| Chapter 223 | Diagnostic Cardiac Catheterization and Angiography |
Section 3. Disorders of Rhythm |
| Chapter 224 | Principles of Electrophysiology |
| Chapter 225 | The Bradyarrhythmias
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| Chapter 226 | The Tachyarrhythmias
Latest Update: |
| Chapter e21 | Atlas of Cardiac Arrhythmias |
Section 4. Disorders of the Heart |
| Chapter 227 | Heart Failure and Cor Pulmonale
Latest Update: |
| Chapter 228 | Cardiac Transplantation and Prolonged Assisted Circulation |
| Chapter 229 | Congenital Heart Disease in the Adult |
| Chapter 230 | Valvular Heart Disease
Latest Update: |
| Chapter 231 | Cardiomyopathy and Myocarditis
Latest Update: |
| Chapter 232 | Pericardial Disease |
| Chapter 233 | Tumors and Trauma of the Heart |
| Chapter 234 | Cardiac Manifestations of Systemic Disease |
Section 5. Vascular Disease |
| Chapter 235 | The Pathogenesis, Prevention, and Treatment of Atherosclerosis |
| Chapter e22 | Atlas of Atherosclerosis |
| Chapter 236 | The Metabolic Syndrome |
| Chapter 237 | Ischemic Heart Disease |
| Chapter 238 | Unstable Angina and Non-ST-Elevation Myocardial Infarction |
| Chapter 239 | ST-Segment Elevation Myocardial Infarction
Latest Update: |
| Chapter 240 | Percutaneous Coronary Intervention |
| Chapter e23 | Atlas of Percutaneous Revascularization |
| Chapter 241 | Hypertensive Vascular Disease |
| Chapter 242 | Diseases of the Aorta |
| Chapter 243 | Vascular Diseases of the Extremities
Latest Update: |
| Chapter 244 | Pulmonary Hypertension |
Part 10. Disorders of the Respiratory System |
Section 1. Diagnosis of Respiratory Disorders |
| Chapter 245 | Approach to the Patient with Disease of the Respiratory System |
| Chapter 246 | Disturbances of Respiratory Function |
| Chapter 247 | Diagnostic Procedures in Respiratory Disease |
| Chapter e24 | Atlas of Chest Imaging |
Section 2. Diseases of the Respiratory System |
| Chapter 248 | Asthma |
| Chapter 249 | Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia |
| Chapter 250 | Environmental Lung Disease |
| Chapter 251 | Pneumonia
Latest Update: |
| Chapter 252 | Bronchiectasis and Lung Abscess |
| Chapter 253 | Cystic Fibrosis |
| Chapter 254 | Chronic Obstructive Pulmonary Disease
Latest Update: |
| Chapter 255 | Interstitial Lung Diseases |
| Chapter e40 | New! Altitude Illness: Acute Mountain Sickness, High-Altitude Pulmonary Edema, and High-Altitude Cerebral Edema |
| Chapter 256 | Deep Venous Thrombosis and Pulmonary Thromboembolism
Latest Update: |
| Chapter 257 | Disorders of the Pleura and Mediastinum |
| Chapter 258 | Disorders of Ventilation
Latest Update: |
| Chapter 259 | Sleep Apnea |
| Chapter 260 | Lung Transplantation
Latest Update: |
Part 11. Critical Care Medicine |
Section 1. Respiratory Critical Care |
| Chapter 261 | Principles of Critical Care Medicine |
| Chapter 262 | Acute Respiratory Distress Syndrome |
| Chapter 263 | Mechanical Ventilatory Support |
Section 2. Shock and Cardiac Arrest |
| Chapter 264 | Approach to the Patient with Shock |
| Chapter 265 | Severe Sepsis and Septic Shock |
| Chapter 266 | Cardiogenic Shock and Pulmonary Edema
Latest Update: |
| Chapter 267 | Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death
Latest Update: |
Section 3. Neurologic Critical Care |
| Chapter 268 | Coma
Latest Update: |
| Chapter 269 | Neurologic Critical Care, Including Hypoxic-Ischemic Encephalopathy and Subarachnoid Hemorrhage
Latest Update: |
Section 4. Oncologic Emergencies |
| Chapter 270 | Oncologic Emergencies |
Part 12. Disorders of the Kidney and Urinary Tract |
| Chapter 271 | Cellular and Molecular Biology of the Kidney |
| Chapter 272 | Adaptation of the Kidney to Renal Injury |
| Chapter 273 | Acute Renal Failure |
| Chapter 274 | Chronic Kidney Disease |
| Chapter 275 | Dialysis in the Treatment of Renal Failure |
| Chapter 276 | Transplantation in the Treatment of Renal Failure |
| Chapter 277 | Glomerular Diseases |
| Chapter 278 | Polycystic Kidney Disease and Other Inherited Tubular Disorders |
| Chapter 279 | Tubulointerstitial Diseases of the Kidney |
| Chapter 280 | Vascular Injury to the Kidney |
| Chapter 281 | Nephrolithiasis |
| Chapter 282 | Urinary Tract Infections, Pyelonephritis, and Prostatitis |
| Chapter 283 | Urinary Tract Obstruction |
Part 13. Disorders of the Gastrointestinal System |
Section 1. Disorders of the Alimentary Tract |
| Chapter 284 | Approach to the Patient with Gastrointestinal Disease
Latest Update: |
| Chapter 285 | Gastrointestinal Endoscopy |
| Chapter e25 | Video Atlas of Gastrointestinal Endoscopy |
| Chapter 286 | Diseases of the Esophagus
Latest Update: |
| Chapter 287 | Peptic Ulcer Disease and Related Disorders
Latest Update: |
| Chapter 288 | Disorders of Absorption |
| Chapter 289 | Inflammatory Bowel Disease
Latest Update: |
| Chapter 290 | Irritable Bowel Syndrome |
| Chapter 291 | Diverticular Disease and Common Anorectal Disorders
Latest Update: |
| Chapter 292 | Mesenteric Vascular Insufficiency |
| Chapter 293 | Acute Intestinal Obstruction |
| Chapter 294 | Acute Appendicitis and Peritonitis |
Section 2. Liver and Biliary Tract Disease |
| Chapter 295 | Approach to the Patient with Liver Disease |
| Chapter 296 | Evaluation of Liver Function |
| Chapter 297 | The Hyperbilirubinemias |
| Chapter 298 | Acute Viral Hepatitis
Latest Update: |
| Chapter 299 | Toxic and Drug-Induced Hepatitis |
| Chapter 300 | Chronic Hepatitis
Latest Update: |
| Chapter 301 | Alcoholic Liver Disease |
| Chapter 302 | Cirrhosis and Its Complications
Latest Update: |
| Chapter e26 | Atlas of Liver Biopsies |
| Chapter 303 | Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver |
| Chapter 304 | Liver Transplantation |
| Chapter 305 | Diseases of the Gallbladder and Bile Ducts |
Section 3. Disorders of the Pancreas |
| Chapter 306 | Approach to the Patient with Pancreatic Disease |
| Chapter 307 | Acute and Chronic Pancreatitis
Latest Update: |
Part 14. Disorders of the Immune System, Connective Tissue, and Joints |
Section 1. The Immune System in Health and Disease |
| Chapter 308 | Introduction to the Immune System |
| Chapter 309 | The Major Histocompatibility Complex |
| Chapter 310 | Primary Immune Deficiency Diseases |
| Chapter e27 | Primary Immunodeficiencies Associated with or Secondary to Other Diseases |
Section 2. Disorders of Immune-Mediated Injury |
| Chapter 311 | Allergies, Anaphylaxis, and Systemic Mastocytosis |
| Chapter 312 | Autoimmunity and Autoimmune Diseases |
| Chapter 313 | Systemic Lupus Erythematosus |
| Chapter 314 | Rheumatoid Arthritis |
| Chapter 315 | Acute Rheumatic Fever |
| Chapter 316 | Systemic Sclerosis (Scleroderma) and Related Disorders |
| Chapter 317 | Sjögren's Syndrome |
| Chapter 318 | The Spondyloarthritides |
| Chapter 319 | The Vasculitis Syndromes
Latest Update: |
| Chapter e28 | Atlas of Clinical Imaging of the Vasculitic Diseases |
| Chapter 320 | Behçet's Syndrome |
| Chapter 321 | Relapsing Polychondritis |
| Chapter 322 | Sarcoidosis |
| Chapter 323 | Familial Mediterranean Fever |
| Chapter 324 | Amyloidosis |
Section 3. Disorders of the Joints and Adjacent Tissues |
| Chapter 325 | Approach to Articular and Musculoskeletal Disorders |
| Chapter 326 | Osteoarthritis |
| Chapter 327 | Gout and Other Crystal-Associated Arthropathies |
| Chapter 328 | Infectious Arthritis
Latest Update: |
| Chapter 329 | Fibromyalgia
Latest Update: |
| Chapter 330 | Arthritis Associated with Systemic Disease and Other Arthritides |
| Chapter 331 | Periarticular Disorders of the Extremities |
Part 15. Endocrinology and Metabolism |
Section 1. Endocrinology |
| Chapter 332 | Principles of Endocrinology |
| Chapter 333 | Disorders of the Anterior Pituitary and Hypothalamus |
| Chapter 334 | Disorders of the Neurohypophysis |
| Chapter 335 | Disorders of the Thyroid Gland |
| Chapter 336 | Disorders of the Adrenal Cortex |
| Chapter 337 | Pheochromocytoma |
| Chapter 338 | Diabetes Mellitus
Latest Update: |
| Chapter 339 | Hypoglycemia |
| Chapter 340 | Disorders of the Testes and Male Reproductive System
Latest Update: |
| Chapter 341 | The Female Reproductive System: Infertility and Contraception |
| Chapter 342 | The Menopause Transition and Postmenopausal Hormone Therapy |
| Chapter 343 | Disorders of Sex Development |
| Chapter 344 | Endocrine Tumors of the Gastrointestinal Tract and Pancreas |
| Chapter 345 | Disorders Affecting Multiple Endocrine Systems |
Section 2. Disorders of Bone and Mineral Metabolism |
| Chapter 346 | Bone and Mineral Metabolism in Health and Disease |
| Chapter 347 | Diseases of the Parathyroid Gland and Other Hyper- and Hypocalcemic Disorders |
| Chapter 348 | Osteoporosis
Latest Update: |
| Chapter 349 | Paget Disease and Other Dysplasias of Bone |
Section 3. Disorders of Intermediary Metabolism |
| Chapter 350 | Disorders of Lipoprotein Metabolism |
| Chapter 351 | Hemochromatosis
Latest Update: |
| Chapter 352 | The Porphyrias |
| Chapter 353 | Disorders of Purine and Pyrimidine Metabolism |
| Chapter 354 | Wilson Disease |
| Chapter 355 | Lysosomal Storage Diseases |
| Chapter 356 | Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism |
| Chapter 357 | Heritable Disorders of Connective Tissue |
| Chapter 358 | Inherited Disorders of Amino Acid Metabolism in Adults |
| Chapter 359 | Inherited Defects of Membrane Transport |
| Chapter e29 | Atlas of Clinical Manifestations of Metabolic Diseases |
Part 16. Neurologic Disorders |
Section 1. Diagnosis of Neurologic Disorders |
| Chapter 360 | Mechanisms of Neurologic Diseases |
| Chapter 361 | Approach to the Patient with Neurologic Disease |
| Chapter 362 | Neuroimaging in Neurologic Disorders
Latest Update: |
| Chapter e30 | Atlas of Neuroimaging |
| Chapter e31 | Electrodiagnostic Studies of Nervous System Disorders: EEG, Evoked Potentials, and EMG |
| Chapter e32 | Technique of Lumbar Puncture |
Section 2. Diseases of the Central Nervous System |
| Chapter 363 | Seizures and Epilepsy
Latest Update: |
| Chapter 364 | Cerebrovascular Diseases
Latest Update: |
| Chapter 365 | Dementia
Latest Update: |
| Chapter 366 | Parkinson's Disease and Other Extrapyramidal Movement Disorders
Latest Update: |
| Chapter 367 | Hyperkinetic Movement Disorders |
| Chapter 368 | Ataxic Disorders |
| Chapter 369 | Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases |
| Chapter 370 | Disorders of the Autonomic Nervous System |
| Chapter 371 | Trigeminal Neuralgia, Bell's Palsy, and Other Cranial Nerve Disorders
Latest Update: |
| Chapter 372 | Diseases of the Spinal Cord |
| Chapter 373 | Concussion and Other Head Injuries |
| Chapter 374 | Primary and Metastatic Tumors of the Nervous System
Latest Update: |
| Chapter 375 | Multiple Sclerosis and Other Demyelinating Diseases
Latest Update: |
| Chapter 376 | Meningitis, Encephalitis, Brain Abscess, and Empyema
Latest Update: |
| Chapter 377 | Chronic and Recurrent Meningitis |
| Chapter 378 | Prion Diseases |
Section 3. Nerve and Muscle Disorders |
| Chapter 379 | Peripheral Neuropathy
Latest Update: |
| Chapter 380 | Guillain-Barré Syndrome and Other Immune-Mediated Neuropathies
Latest Update: |
| Chapter 381 | Myasthenia Gravis and Other Diseases of the Neuromuscular Junction
Latest Update: |
| Chapter 382 | Muscular Dystrophies and Other Muscle Diseases
Latest Update: |
| Chapter 383 | Polymyositis, Dermatomyositis, and Inclusion Body Myositis |
| Chapter e33 | Special Issues in Inpatient Neurologic Consultation
Latest Update: |
Section 4. Chronic Fatigue Syndrome |
| Chapter 384 | Chronic Fatigue Syndrome |
Section 5. Psychiatric Disorders |
| Chapter 385 | Biology of Psychiatric Disorders |
| Chapter 386 | Mental Disorders
Latest Update: |
Section 6. Alcoholism and Drug Dependency |
| Chapter 387 | Alcohol and Alcoholism |
| Chapter 388 | Opioid Drug Abuse and Dependence |
| Chapter 389 | Cocaine and Other Commonly Abused Drugs |
| Chapter 390 | Nicotine Addiction |
Part 17. Poisoning, Drug Overdose, and Envenomation |
| Chapter e34 | Heavy Metal Poisoning |
| Chapter e35 | Poisoning and Drug Overdosage |
| Chapter 391 | Disorders Caused by Reptile Bites and Marine Animal Exposures |
| Chapter 392 | Ectoparasite Infestations and Arthropod Bites and Stings |
Part 18. e-Chapters from International Advisory Editors |
| Chapter e36 | Pulmonary Biomarkers in COPD |
| Chapter e37 | Chagas' Disease: Advances in Diagnosis and Management |
| Chapter e38 | The Polypill |
| Chapter e39 | Mitochondrial DNA and Heritable Traits and Diseases |
Appendix: Laboratory Values of Clinical Importance |
The e-chapter logo indicates a chapter that is currently available only online. |