Skip Navigation

Link to  the National Institutes of Health NIDA NEWS NIDA News RSS Feed
The Science of Drug Abuse and Addiction from the National Institute on Drug Abuse Keep Your Body Healthy
Go to the Home pageGo to the About Nida pageGo to the News pageGo to the Meetings & Events pageGo to the Funding pageGo to the Publications page
PhysiciansResearchersParents/TeachersStudents/Young AdultsEn Español Drugs of Abuse & Related Topics

NIDA Home > Publications > Research Monographs >    

Rx :3 x /Week Laam Alternative to Methadone



NIDA Research Monograph, Number 8 [Printed in 1976]

Get Adobe Reader This monograph is not available by chapter. The Table of Contents (below) is shown to assist in locating information prior to downloading the monograph.

Download Monograph 8 - Rx :3 x /Week Laam Alternative to Methadone (1.1 MB PDF format)


Table of Contents

Foreword-----V
Robert L. DuPont, M.D.

Introduction-----1
Jack Blaine, M.D. and Pierre Renault, M.D.

The Chemistry of LAAM-----10
Sydney Archer, Ph.D.

PRECLINICAL STUDIES

Pharmacology of LAAM-----15
Sydney Archer, Ph.D.

Toxicology of LAAM-----29
Ms. Ann Wolven and Sydney Archer, Ph.D.

CLINICAL STUDIES

Phase I-----39
Ralph M. Sollod, M.S., and Marcia G. Goldstein, M.A.

Selected Clinical Studies Synopses-----52

Sumnary of Veterans Administration Phase II Cooperative Study for LAAM and Methadone-----94
Walter Ling, M.D. V. Charles Chamvastra, M.D. Samuel C. Kaim, M.D. C. James Klett, Ph.D.

Summary of SAODAP Phase II Cooperative Study of LAAM vs. Methadone-----103
Walter Ling, M.D. C. James Klett, Ph.D. Roderic D. Gillis

Phase III Clinical Study of Levo-Alpha-Acetylmethadol-----109
John A. Whysener, M.D., Ph.D.

The Use of LAAM in Treatment-----112
James Cooper, M.D.

A Clinical Experience with LAAM-----115
Avram Goldstein, M.D.

A LAAM Bibliography
Preclinical-----118
Clinical-----123




NIDA Home | Site Map | Search | FAQs | Accessibility | Privacy | FOIA (NIH) | Employment | Print Version


National Institutes of Health logo_Department of Health and Human Services Logo The National Institute on Drug Abuse (NIDA) is part of the National Institutes of Health (NIH) , a component of the U.S. Department of Health and Human Services. Questions? See our Contact Information. Last updated on Tuesday, July 22, 2008. The U.S. government's official web portal