Dying Young as Late as Possible: Planarians, Regeneration and Stem Cells |
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| Air date: | Wednesday, September 03, 2008, 3:00:00 PM |
| Category: | Wednesday Afternoon Lectures |
| Runtime: | 60 minutes |
| NLM Title: | Dying young as late as possible : planarians, regeneration, and stem cells [electronic resource] / Alejandro Sánchez Alvarado. |
| Series: | NIH director's Wednesday afternoon lecture series |
| Author: | Sánchez Alvarado, Alejandro. National Institutes of Health (U.S.) |
| Publisher: | [Bethesda, Md. : National Institutes of Health, 2008] |
| Other Title(s): | NIH director's Wednesday afternoon lecture series |
| Abstract: | (CIT): TALK SUMMARY: It is paradoxical that for many animals (including humans), the apparent anatomical stability of their adult bodies is maintained by constant change. Under normal physiological conditions, the functions of many organs depend on the continuous destruction and renewal of their cells. Equally remarkable is the fact the adult tissues and organs of many organisms can be fully restored after amputation. In fact, it appears that metazoans have evolved a series of renewal and repair mechanisms to respond to both trauma and normal wear and tear. Moreover, these mechanisms are under tight regulatory control such that organismal form and function can be maintained throughout life. As important as repair and restoration are to survival of multicellular organisms, we know little about how these processes are effected and regulated at the cellular and molecular levels. Here, I will discuss how the study of a simple metazoan, the planarian Schmidtea mediterranea, is beginning to shed light on the way adult animals regulate tissue homeostasis and the replacement of the body parts lost to injury. |
| Subjects: | Aging--physiology Cell Proliferation Planarians Regeneration |
| Publication Types: | Government Publications Lectures |
| Download: | Download
Video How to download a Videocast |
| NLM Classification: | QH 499 |
| NLM ID: | 101486617 |
| CIT File ID: | 14623 |
| CIT Live ID: | 6984 |
| Permanent link: | http://videocast.nih.gov/launch.asp?14623 |
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Enhanced Audio Podcast | 1:11:05 |
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Enhanced Video Podcast | 1:11:05 | |