Tissue Engineering and the Challenges of Imitating Nature

 


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Air date: Wednesday, October 17, 2007, 3:00:00 PM
Category: Wednesday Afternoon Lectures
Runtime: 74 minutes
NLM Title: Tissue engineering and the challenges of imitating nature [electronic resource] / Gordana Vunjak-Novakovic.
Series: The NIH Wednesday afternoon lecture
Author: Vunjak-Novakovic, Gordana.
National Institutes of Health (U.S.)
Publisher: [Bethesda, Md. : National Institutes of Health, 2007]
Other Title(s): The NIH Wednesday afternoon lecture
Abstract: (CIT): Tissue engineering is an area of science and technology expected to improve our life, by offering new treatment options for regenerative medicine. By creating biological substitutes of native tissues, tissue engineering can help outlive a failure of any of our organs. The overall objective of tissue engineering is to fully restore the lost tissue function. Engineered tissues of sufficiently high fidelity can also provide physiologically relevant yet controllable models for fundamental research - for example, to study stem cells in a native-like three-dimensional context, or within a model of disease. The clinical and scientific utility of tissue engineering certainly depends on our ability to predictably direct the cells to express the right phenotype in the right place and at the right time. We are observing that the same factors that regulate tissue development in vivo (molecular and physical) can be used to direct cell fate and tissue assembly in vitro. Therefore, tissue engineering is largely an effort of imitating nature as it tends to recapitulate the native environment during tissue development and remodeling. This talk will discuss biologically inspired tissue engineering, and the utilization of stem cells and advanced culture systems for regenerative medicine and biological research.
Subjects: Organ Culture Techniques
Stem Cells
Tissue Engineering
Publication Types: Government Publications
Lectures
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NLM Classification: QT 37
NLM ID: 101319971
CIT File ID: 14079
CIT Live ID: 6154
Permanent link: http://videocast.nih.gov/launch.asp?14079

 

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