Normal and Neoplastic Stem Cells

 


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Air date: Wednesday, June 18, 2008, 3:00:00 PM
Category: Wednesday Afternoon Lectures
Runtime: 75 minutes
NLM Title: Normal and neoplastic stem cells [electronic resource] / Irving L. Weissman.
Series: NIH director's Wednesday afternoon lecture series
Author: Weissman, Irving L.
National Institutes of Health (U.S.)
Publisher: [Bethesda, Md. : National Institutes of Health, 2008]
Other Title(s): NIH director's Wednesday afternoon lecture series
Abstract: (CIT): Following embryonic development, most of our tissues and organs are continuously regenerated from tissue/organ specific stem cells. The principal property that distinguishes such stem cells from their daughter cells is self-renewal; when stem cells divide they give rise to stem cells (by self-renewal) and progenitors (by differentiation). In most tissues only the primitive stem cells self-renew. Stem cell isolation and transplantation is the basis for regenerative medicine. Self-renewal is dangerous, and therefore strictly regulated. Poorly regulated self-renewal can lead to the genesis of cancer stem cells, the only self-renewing cells in the cancerous tumor.
Subjects: Neoplastic Stem Cells--physiology
Stem Cells--physiology
Publication Types: Government Publications
Lectures
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NLM Classification: QZ 202
NLM ID: 101478257
CIT File ID: 14565
CIT Live ID: 6740
Permanent link: http://videocast.nih.gov/launch.asp?14565

 

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