"Circuit Neuromics": The New Path to Understanding the Genetic and Neural Causes of Mood Disorders |
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| Launch in standalone player | |
| Air date: | Wednesday, June 04, 2008, 3:00:00 PM |
| Category: | Wednesday Afternoon Lectures |
| Runtime: | 75 minutes |
| NLM Title: | "Circuit neuromics" : the new path to understanding the genetic and neural causes of mood disorders [electronic resource] / Huda Akil. |
| Series: | NIH director's Wednesday afternoon lecture series |
| Author: | Akil, H. National Institutes of Health (U.S.) |
| Publisher: | [Bethesda, Md. : National Institutes of Health, 2008] |
| Other Title(s): | NIH director's Wednesday afternoon lecture series |
| Abstract: | (CIT): This lecture will summarize our research aimed at understanding the biology of mood disorders, including efforts at identifying genetic vulnerability factors and at characterizing the consequences of these illnesses on the brain. It will describe a combination of genome-wide association and candidate genetic studies, post-mortem gene expression profiling and downstream analyses in animal models. It will offer examples of how these "discovery approaches" can lead to unexpected insights into the molecular neurobiology of mood and emotions. This lecture will also discuss the limitations of the strategies used to date given the unique challenges intrinsic to complex brain diseases, particularly mood disorders. It will end by proposing an integrated approach, termed "Circuit Neuromics"--a framework for meeting these challenges, and for discovering both the antecedents of dysregulated moods and the consequences of these disorders on brain function. |
| Subjects: | Genetic Predisposition to Disease Mood Disorders--genetics Mood Disorders--physiopathology |
| Publication Types: | Government Publications Lectures |
| Download: | Download
Video How to download a Videocast |
| NLM Classification: | WM 171 |
| NLM ID: | 101478234 |
| CIT File ID: | 14537 |
| CIT Live ID: | 6226 |
| Permanent link: | http://videocast.nih.gov/launch.asp?14537 |
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Enhanced Audio Podcast | 59:08 |
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Enhanced Video Podcast | 59:08 | |