3' -UTR-mediated translational regulation |
Reactome Imported |
3' -UTR-mediated translational regulation |
Reactome Imported |
Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression |
Reactome Imported |
APC-Cdc20 mediated degradation of Nek2A |
Reactome Imported |
Apoptosis |
Reactome Imported |
Subnetwork: Activation and oligomerization of BAK protein |
Reactome Imported |
Subnetwork: Activation of BAD and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of BH3-only proteins |
Reactome Imported |
Subnetwork: Activation of BIM and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of BMF and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of DNA fragmentation factor |
Reactome Imported |
Subnetwork: Activation of NOXA and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of PUMA and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of Pro-Caspase 8 |
Reactome Imported |
Subnetwork: Activation of caspases through apoptosome-mediated cleavage |
Reactome Imported |
Subnetwork: Activation, myristolyation of BID and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation, translocation and oligomerization of BAX |
Reactome Imported |
Subnetwork: Apoptosis induced DNA fragmentation |
Reactome Imported |
Subnetwork: Apoptotic cleavage of cell adhesion proteins |
Reactome Imported |
Subnetwork: Apoptotic cleavage of cellular proteins |
Reactome Imported |
Subnetwork: Apoptotic execution phase |
Reactome Imported |
Subnetwork: Apoptotic factor-mediated response |
Reactome Imported |
Subnetwork: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members |
Reactome Imported |
Subnetwork: Breakdown of the nuclear lamina |
Reactome Imported |
Subnetwork: Caspase-8 is formed from procaspase-8 |
Reactome Imported |
Subnetwork: Caspase-mediated cleavage of cytoskeletal proteins |
Reactome Imported |
Subnetwork: Cytochrome c-mediated apoptotic response |
Reactome Imported |
Subnetwork: Death Receptor Signalling |
Reactome Imported |
Subnetwork: Extrinsic Pathway for Apoptosis |
Reactome Imported |
Subnetwork: FasL/ CD95L signaling |
Reactome Imported |
Subnetwork: Formation of apoptosome |
Reactome Imported |
Subnetwork: Intrinsic Pathway for Apoptosis |
Reactome Imported |
Subnetwork: Regulation of Apoptosis |
Reactome Imported |
Subnetwork: Regulation of PAK-2p34 activity by PS-GAP/RHG10 |
Reactome Imported |
Subnetwork: Regulation of activated PAK-2p34 by proteasome mediated degradation |
Reactome Imported |
Subnetwork: Release of apoptotic factors from the mitochondria |
Reactome Imported |
Subnetwork: SMAC binds to IAPs |
Reactome Imported |
Subnetwork: SMAC-mediated apoptotic response |
Reactome Imported |
Subnetwork: SMAC-mediated dissociation of IAP:caspase complexes |
Reactome Imported |
Subnetwork: Stimulation of the cell death response by PAK-2p34 |
Reactome Imported |
Subnetwork: TNF signaling |
Reactome Imported |
Subnetwork: TRAIL signaling |
Reactome Imported |
Biological oxidations |
Reactome Imported |
Subnetwork: Acetaldehyde is oxidized by NAD+ to form acetate, NADH, and H+ |
Reactome Imported |
Subnetwork: Acetate, ATP, and coenzyme A react to form acetyl CoA, AMP, and pyrophosphate |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Alcohol Dehydrogenase |
Reactome Imported |
Subnetwork: Aldehyde Dehydrogenase |
Reactome Imported |
Subnetwork: Amine Oxidase reactions |
Reactome Imported |
Subnetwork: Amino Acid conjugation |
Reactome Imported |
Subnetwork: Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 |
Reactome Imported |
Subnetwork: COX reactions |
Reactome Imported |
Subnetwork: CYP2E1 reactions |
Reactome Imported |
Subnetwork: Conjugation of benzoate with glycine |
Reactome Imported |
Subnetwork: Conjugation of carboxylic acids |
Reactome Imported |
Subnetwork: Conjugation of phenylacetate with glutamine |
Reactome Imported |
Subnetwork: Conjugation of salicylate with glycine |
Reactome Imported |
Subnetwork: Cytochrome P450 - arranged by substrate type |
Reactome Imported |
Subnetwork: Cytosolic sulfonation of small molecules |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Endogenous sterols |
Reactome Imported |
Subnetwork: Ethanol catabolism |
Reactome Imported |
Subnetwork: Ethanol is oxidized by NAD+ to form acetaldehyde, NADH, and H+ |
Reactome Imported |
Subnetwork: FMO oxidizes nucleophiles |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Formation of the active cofactor, UDP-glucuronate |
Reactome Imported |
Subnetwork: Glucuronidation |
Reactome Imported |
Subnetwork: Glutathione conjugation |
Reactome Imported |
Subnetwork: Glutathione synthesis |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 |
Reactome Imported |
Subnetwork: Phase 1 - Functionalization of compounds |
Reactome Imported |
Subnetwork: Phase II conjugation |
Reactome Imported |
Subnetwork: Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs |
Reactome Imported |
Subnetwork: Sterols are 12-hydroxylated by CYP8B1 |
Reactome Imported |
|
Reactome Imported |
|
Reactome Imported |
|
Reactome Imported |
Botulinum neurotoxicity |
Reactome Imported |
Subnetwork: BoNT Light Chain Types A, C1, E cleave SNAP-25 |
Reactome Imported |
Subnetwork: BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin |
Reactome Imported |
Subnetwork: Proteolytic cleavage of SNARE complex proteins |
Reactome Imported |
Subnetwork: Translocation of BoNT Light chain |
Reactome Imported |
Breakdown of hydrogen peroxide to water and molecular oxygen |
Reactome Imported |
Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
Reactome Imported |
Cell Cycle Checkpoints |
Reactome Imported |
Subnetwork: Activation of ATR in response to replication stress |
Reactome Imported |
Subnetwork: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
Reactome Imported |
Subnetwork: Amplification of signal from the kinetochores |
Reactome Imported |
Subnetwork: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex |
Reactome Imported |
Subnetwork: G1/S DNA Damage Checkpoints |
Reactome Imported |
Subnetwork: G2/M Checkpoints |
Reactome Imported |
Subnetwork: G2/M DNA damage checkpoint |
Reactome Imported |
Subnetwork: G2/M DNA replication checkpoint |
Reactome Imported |
Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex |
Reactome Imported |
Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
Reactome Imported |
Subnetwork: Mitotic Spindle Checkpoint |
Reactome Imported |
Subnetwork: Stabilization of p53 |
Reactome Imported |
Subnetwork: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A |
Reactome Imported |
Subnetwork: p53-Dependent G1 DNA Damage Response |
Reactome Imported |
Subnetwork: p53-Dependent G1/S DNA damage checkpoint |
Reactome Imported |
Subnetwork: p53-Independent DNA Damage Response |
Reactome Imported |
Subnetwork: p53-Independent G1/S DNA damage checkpoint |
Reactome Imported |
Cell Cycle, Mitotic |
Reactome Imported |
Subnetwork: APC/C-mediated degradation of cell cycle proteins |
Reactome Imported |
Subnetwork: APC/C:Cdc20 mediated degradation of Cyclin B |
Reactome Imported |
Subnetwork: APC/C:Cdc20 mediated degradation of Securin |
Reactome Imported |
Subnetwork: APC/C:Cdc20 mediated degradation of mitotic proteins |
Reactome Imported |
Subnetwork: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
Reactome Imported |
Subnetwork: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
Reactome Imported |
Subnetwork: Activation of the pre-replicative complex |
Reactome Imported |
Subnetwork: Assembly of the ORC complex at the origin of replication |
Reactome Imported |
Subnetwork: Assembly of the pre-replicative complex |
Reactome Imported |
Subnetwork: Autodegradation of Cdh1 by Cdh1:APC/C |
Reactome Imported |
Subnetwork: CDC6 association with the ORC:origin complex |
Reactome Imported |
Subnetwork: CDK-mediated phosphorylation and removal of Cdc6 |
Reactome Imported |
Subnetwork: CDT1 association with the CDC6:ORC:origin complex |
Reactome Imported |
Subnetwork: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
Reactome Imported |
Subnetwork: Cyclin A/B1 associated events during G2/M transition |
Reactome Imported |
Subnetwork: Cyclin A:Cdk2-associated events at S phase entry |
Reactome Imported |
Subnetwork: Cyclin B2 mediated events |
Reactome Imported |
Subnetwork: Cyclin D associated events in G1 |
Reactome Imported |
Subnetwork: Cyclin E associated events during G1/S transition |
Reactome Imported |
Subnetwork: DNA replication initiation |
Reactome Imported |
Subnetwork: DNA strand elongation |
Reactome Imported |
Subnetwork: E2F mediated regulation of DNA replication |
Reactome Imported |
Subnetwork: E2F-enabled inhibition of pre-replication complex formation |
Reactome Imported |
|
Reactome Imported |
Subnetwork: G1/S Transition |
Reactome Imported |
|
Reactome Imported |
Subnetwork: G2/M Transition |
Reactome Imported |
Subnetwork: Golgi Cisternae Pericentriolar Stack Reorganization |
Reactome Imported |
Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex |
Reactome Imported |
Subnetwork: Inhibition of replication initiation of damaged DNA by Rb/E2F1 |
Reactome Imported |
Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
Reactome Imported |
Subnetwork: Lagging Strand Synthesis |
Reactome Imported |
Subnetwork: Leading Strand Synthesis |
Reactome Imported |
|
Reactome Imported |
Subnetwork: M/G1 Transition |
Reactome Imported |
Subnetwork: Mitotic Metaphase/Anaphase Transition |
Reactome Imported |
Subnetwork: Mitotic Prometaphase |
Reactome Imported |
Subnetwork: Mitotic Prophase |
Reactome Imported |
Subnetwork: Mitotic Telophase /Cytokinesis |
Reactome Imported |
Subnetwork: Orc1 removal from chromatin |
Reactome Imported |
Subnetwork: Phosphorylation of Emi1 |
Reactome Imported |
Subnetwork: Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes |
Reactome Imported |
Subnetwork: Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes |
Reactome Imported |
Subnetwork: Phosphorylation of the APC/C |
Reactome Imported |
Subnetwork: Polo-like kinase mediated events |
Reactome Imported |
Subnetwork: Polymerase switching |
Reactome Imported |
Subnetwork: Processive synthesis on the lagging strand |
Reactome Imported |
Subnetwork: Regulation of APC/C activators between G1/S and early anaphase |
Reactome Imported |
Subnetwork: Removal of the Flap Intermediate |
Reactome Imported |
|
Reactome Imported |
Subnetwork: SCF(Skp2)-mediated degradation of p27/p21 |
Reactome Imported |
Subnetwork: SCF-beta-TrCP mediated degradation of Emi1 |
Reactome Imported |
Subnetwork: Switching of origins to a post-replicative state |
Reactome Imported |
Subnetwork: Synthesis of DNA |
Reactome Imported |
Subnetwork: Ubiquitin-dependent degradation of Cyclin D |
Reactome Imported |
Subnetwork: Ubiquitin-dependent degradation of Cyclin D1 |
Reactome Imported |
Subnetwork: Unwinding of DNA |
Reactome Imported |
DNA Repair |
Reactome Imported |
Subnetwork: ABH2 mediated Reversal of Alkylation Damage |
Reactome Imported |
Subnetwork: ABH3 mediated Reversal of Alkylation Damage |
Reactome Imported |
Subnetwork: ATM mediated phosphorylation of repair proteins |
Reactome Imported |
Subnetwork: ATM mediated response to DNA double-strand break |
Reactome Imported |
Subnetwork: Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks |
Reactome Imported |
Subnetwork: Assembly of the RAD51-ssDNA nucleoprotein complex |
Reactome Imported |
Subnetwork: Base Excision Repair |
Reactome Imported |
Subnetwork: Base-Excision Repair, AP Site Formation |
Reactome Imported |
Subnetwork: Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
Reactome Imported |
Subnetwork: Cleavage of the damaged purine |
Reactome Imported |
Subnetwork: Cleavage of the damaged pyrimidine |
Reactome Imported |
Subnetwork: DNA Damage Bypass |
Reactome Imported |
Subnetwork: DNA Damage Recognition in GG-NER |
Reactome Imported |
Subnetwork: DNA Damage Reversal |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Depyrimidination |
Reactome Imported |
Subnetwork: Displacement of DNA glycosylase by APE1 |
Reactome Imported |
Subnetwork: Double-Strand Break Repair |
Reactome Imported |
Subnetwork: Dual incision reaction in GG-NER |
Reactome Imported |
Subnetwork: Dual incision reaction in TC-NER |
Reactome Imported |
Subnetwork: Formation of incision complex in GG-NER |
Reactome Imported |
Subnetwork: Formation of transcription-coupled NER (TC-NER) repair complex |
Reactome Imported |
Subnetwork: Gap-filling DNA repair synthesis and ligation in GG-NER |
Reactome Imported |
Subnetwork: Gap-filling DNA repair synthesis and ligation in TC-NER |
Reactome Imported |
Subnetwork: Global Genomic NER (GG-NER) |
Reactome Imported |
Subnetwork: Homologous DNA pairing and strand exchange |
Reactome Imported |
Subnetwork: Homologous Recombination Repair |
Reactome Imported |
Subnetwork: Homologous recombination repair of replication-independent double-strand breaks |
Reactome Imported |
Subnetwork: MRN complex relocalizes to nuclear foci |
Reactome Imported |
Subnetwork: Nonhomologous End-joining (NHEJ) |
Reactome Imported |
Subnetwork: Nucleotide Excision Repair |
Reactome Imported |
Subnetwork: Presynaptic phase of homologous DNA pairing and strand exchange |
Reactome Imported |
Subnetwork: Processing of DNA double-strand break ends |
Reactome Imported |
Subnetwork: Processing of DNA ends prior to end rejoining |
Reactome Imported |
Subnetwork: Recognition and association of DNA glycosylase with site containing an affected purine |
Reactome Imported |
Subnetwork: Recognition and association of DNA glycosylase with site containing an affected pyrimidine |
Reactome Imported |
Subnetwork: Recruitment of repair and signaling proteins to double-strand breaks |
Reactome Imported |
Subnetwork: Removal of DNA patch containing abasic residue |
Reactome Imported |
Subnetwork: Repair synthesis for gap-filling by DNA polymerase in TC-NER |
Reactome Imported |
Subnetwork: Repair synthesis of patch ~27-30 bases long by DNA polymerase |
Reactome Imported |
Subnetwork: Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
Reactome Imported |
Subnetwork: Resolution of AP sites via the single-nucleotide replacement pathway |
Reactome Imported |
Subnetwork: Resolution of Abasic Sites (AP sites) |
Reactome Imported |
Subnetwork: Resolution of D-loop structures |
Reactome Imported |
Subnetwork: Resolution of D-loop structures through Holliday junction intermediates |
Reactome Imported |
Subnetwork: Resolution of D-loop structures through synthesis-dependent strand-annealing |
Reactome Imported |
Subnetwork: Reversal of Alkylation Damage By DNA Dioxygenases |
Reactome Imported |
Subnetwork: Transcription-coupled NER (TC-NER) |
Reactome Imported |
Subnetwork: Translesion synthesis by DNA polymerases bypassing lesion on DNA template |
Reactome Imported |
Subnetwork: Translesion synthesis by HREV1 |
Reactome Imported |
Subnetwork: Translesion synthesis by Pol eta |
Reactome Imported |
Subnetwork: Translesion synthesis by Pol zeta |
Reactome Imported |
DNA Replication |
Reactome Imported |
Subnetwork: Activation of the pre-replicative complex |
Reactome Imported |
Subnetwork: Assembly of the ORC complex at the origin of replication |
Reactome Imported |
Subnetwork: Assembly of the pre-replicative complex |
Reactome Imported |
Subnetwork: Association of licensing factors with the pre-replicative complex |
Reactome Imported |
Subnetwork: CDC6 association with the ORC:origin complex |
Reactome Imported |
Subnetwork: CDK-mediated phosphorylation and removal of Cdc6 |
Reactome Imported |
Subnetwork: CDT1 association with the CDC6:ORC:origin complex |
Reactome Imported |
Subnetwork: DNA Replication Pre-Initiation |
Reactome Imported |
Subnetwork: DNA replication initiation |
Reactome Imported |
Subnetwork: DNA strand elongation |
Reactome Imported |
Subnetwork: Lagging Strand Synthesis |
Reactome Imported |
Subnetwork: Leading Strand Synthesis |
Reactome Imported |
Subnetwork: Orc1 removal from chromatin |
Reactome Imported |
Subnetwork: Polymerase switching |
Reactome Imported |
Subnetwork: Processive synthesis on the lagging strand |
Reactome Imported |
Subnetwork: Regulation of DNA replication |
Reactome Imported |
Subnetwork: Removal of licensing factors from origins |
Reactome Imported |
Subnetwork: Removal of the Flap Intermediate |
Reactome Imported |
Subnetwork: Switching of origins to a post-replicative state |
Reactome Imported |
Subnetwork: Unwinding of DNA |
Reactome Imported |
Electron Transport Chain |
Reactome Imported |
Elongation arrest and recovery |
Reactome Imported |
Formation of PAPS |
Reactome Imported |
Gap junction trafficking and regulation |
Reactome Imported |
Subnetwork: Formation of annular gap junctions |
Reactome Imported |
Subnetwork: Gap junction assembly |
Reactome Imported |
Subnetwork: Gap junction degradation |
Reactome Imported |
Subnetwork: Gap junction trafficking |
Reactome Imported |
Subnetwork: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane |
Reactome Imported |
Subnetwork: Oligomerization of connexins into connexons |
Reactome Imported |
Subnetwork: Regulation of gap junction activity |
Reactome Imported |
Subnetwork: Transport of connexins along the secretory pathway |
Reactome Imported |
Subnetwork: Transport of connexons to the plasma membrane |
Reactome Imported |
Subnetwork: c-src mediated regulation of Cx43 function and closure of gap junctions |
Reactome Imported |
Gene Expression |
Reactome Imported |
Subnetwork: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
Reactome Imported |
Subnetwork: Cap-dependent Translation Initiation |
Reactome Imported |
Subnetwork: Elongation and Processing of Capped Transcripts |
Reactome Imported |
Subnetwork: Elongation of Intron-Containing Transcripts and co-transcriptional mRNA splicing |
Reactome Imported |
Subnetwork: Eukaryotic Translation Elongation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Initiation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Termination |
Reactome Imported |
Subnetwork: Formation and Maturation of mRNA Transcript |
Reactome Imported |
Subnetwork: Formation of RNA Pol II elongation complex |
Reactome Imported |
Subnetwork: Formation of a pool of free 40S subunits |
Reactome Imported |
Subnetwork: Formation of the Early Elongation Complex |
Reactome Imported |
Subnetwork: Formation of the ternary complex, and subsequently, the 43S complex |
Reactome Imported |
Subnetwork: GTP hydrolysis and joining of the 60S ribosomal subunit |
Reactome Imported |
Subnetwork: Generic Transcription Pathway |
Reactome Imported |
Subnetwork: Notch-HLH transcription pathway |
Reactome Imported |
Subnetwork: Peptide chain elongation |
Reactome Imported |
Subnetwork: Post-Elongation Processing of Intron-Containing pre-mRNA |
Reactome Imported |
Subnetwork: Post-Elongation Processing of Intronless pre-mRNA |
Reactome Imported |
Subnetwork: Post-Elongation Processing of the Transcript |
Reactome Imported |
Subnetwork: Processing of Capped Intronless Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Intronless Pre-mRNAs |
Reactome Imported |
Subnetwork: RNA Polymerase II Promoter Escape |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation And Promoter Clearance |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Pre-Initiation |
Reactome Imported |
Subnetwork: Recycling of eIF2:GDP |
Reactome Imported |
Subnetwork: Ribosomal scanning and start codon recognition |
Reactome Imported |
Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP independent Processing of Histone Pre-mRNAs |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Translation initiation complex formation |
Reactome Imported |
Subnetwork: Transport of Mature Transcript to Cytoplasm |
Reactome Imported |
Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts |
Reactome Imported |
Subnetwork: Transport of the SLBP Dependant Mature mRNA |
Reactome Imported |
Subnetwork: Transport of the SLBP independent Mature mRNA |
Reactome Imported |
Subnetwork: mRNA 3'-end processing |
Reactome Imported |
|
Reactome Imported |
Subnetwork: mRNA Splicing |
Reactome Imported |
Subnetwork: mRNA Splicing - Major Pathway |
Reactome Imported |
Subnetwork: mRNA Splicing - Minor Pathway |
Reactome Imported |
HIV Infection |
Reactome Imported |
Subnetwork: 2-LTR circle formation |
Reactome Imported |
Subnetwork: APOBEC3G mediated resistance to HIV-1 infection |
Reactome Imported |
Subnetwork: Abortive elongation of HIV-1 transcript in the absence of Tat |
Reactome Imported |
Subnetwork: Autointegration results in viral DNA circles |
Reactome Imported |
Subnetwork: Binding and entry of HIV virion |
Reactome Imported |
Subnetwork: Early Phase of HIV Life Cycle |
Reactome Imported |
Subnetwork: Formation of HIV-1 elongation complex containing HIV-1 Tat |
Reactome Imported |
Subnetwork: Formation of the HIV-1 Early Elongation Complex |
Reactome Imported |
Subnetwork: HIV Life Cycle |
Reactome Imported |
Subnetwork: HIV-1 Transcription Elongation |
Reactome Imported |
Subnetwork: HIV-1 Transcription Initiation |
Reactome Imported |
Subnetwork: HIV-1 Transcription Pre-Initiation |
Reactome Imported |
Subnetwork: Host Interactions of HIV factors |
Reactome Imported |
Subnetwork: Integration of provirus |
Reactome Imported |
Subnetwork: Integration of viral DNA into host genomic DNA |
Reactome Imported |
Subnetwork: Interactions of Rev with host cellular proteins |
Reactome Imported |
Subnetwork: Interactions of Tat with host cellular proteins |
Reactome Imported |
Subnetwork: Interactions of Vpr with host cellular proteins |
Reactome Imported |
Subnetwork: Late Phase of HIV Life Cycle |
Reactome Imported |
Subnetwork: Minus-strand DNA synthesis |
Reactome Imported |
Subnetwork: Nef Mediated CD4 Down-regulation |
Reactome Imported |
Subnetwork: Nef Mediated CD8 Down-regulation |
Reactome Imported |
Subnetwork: Nef and signal transduction |
Reactome Imported |
Subnetwork: Nef mediated downregulation of CD28 cell surface expression |
Reactome Imported |
Subnetwork: Nef mediated downregulation of MHC class I complex cell surface expression |
Reactome Imported |
Subnetwork: Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
Reactome Imported |
Subnetwork: Nuclear import of Rev protein |
Reactome Imported |
Subnetwork: Plus-strand DNA synthesis |
Reactome Imported |
Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE |
Reactome Imported |
Subnetwork: RNA Polymerase II HIV-1 Promoter Escape |
Reactome Imported |
Subnetwork: Rev-mediated nuclear export of HIV-1 RNA |
Reactome Imported |
Subnetwork: Reverse Transcription of HIV RNA |
Reactome Imported |
Subnetwork: Tat-mediated elongation of the HIV-1 transcript |
Reactome Imported |
Subnetwork: The role of Nef in HIV-1 replication and disease pathogenesis |
Reactome Imported |
Subnetwork: Transcription of the HIV genome |
Reactome Imported |
Subnetwork: Uncoating of the HIV Virion |
Reactome Imported |
Subnetwork: Vif-mediated degradation of APOBEC3G |
Reactome Imported |
Subnetwork: Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization |
Reactome Imported |
Subnetwork: Vpr-mediated nuclear import of PICs |
Reactome Imported |
Subnetwork: Vpu mediated degradation of CD4 |
Reactome Imported |
HIV-1 elongation arrest and recovery |
Reactome Imported |
Hemostasis |
Reactome Imported |
Subnetwork: Basigin interactions |
Reactome Imported |
Subnetwork: Cell surface interactions at the vascular wall |
Reactome Imported |
Subnetwork: Collagen adhesion via Gp IV |
Reactome Imported |
Subnetwork: Collagen adhesion via alpha 2 beta 1 glycoprotein |
Reactome Imported |
Subnetwork: Collagen-mediated activation cascade |
Reactome Imported |
Subnetwork: Common Pathway |
Reactome Imported |
Subnetwork: Disinhibition of SNARE formation |
Reactome Imported |
Subnetwork: Dissolution of Fibrin Clot |
Reactome Imported |
Subnetwork: Effects of IP3 |
Reactome Imported |
Subnetwork: Effects on Ca++ levels |
Reactome Imported |
Subnetwork: Elevation of cytosolic Ca++ levels |
Reactome Imported |
Subnetwork: Exocytosis of Alpha granule |
Reactome Imported |
Subnetwork: Exocytosis of Dense granule |
Reactome Imported |
Subnetwork: Extrinsic Pathway |
Reactome Imported |
Subnetwork: Formation of Fibrin Clot (Clotting Cascade) |
Reactome Imported |
Subnetwork: Formation of Platelet plug |
Reactome Imported |
Subnetwork: Further platelet releasate |
Reactome Imported |
Subnetwork: G alpha 12 cascade |
Reactome Imported |
Subnetwork: G alpha Q cascade |
Reactome Imported |
Subnetwork: G-protein cascades |
Reactome Imported |
Subnetwork: Intrinsic Pathway |
Reactome Imported |
Subnetwork: PECAM1 interactions |
Reactome Imported |
Subnetwork: PLC-mediated hydrolysis |
Reactome Imported |
Subnetwork: Phospholipase-mediated signalling |
Reactome Imported |
Subnetwork: Platelet Activation |
Reactome Imported |
Subnetwork: Platelet Adhesion to exposed collagen |
Reactome Imported |
Subnetwork: Platelet activation triggers |
Reactome Imported |
Subnetwork: Platelet degranulation |
Reactome Imported |
Subnetwork: Plug Formation |
Reactome Imported |
Subnetwork: Response to elevated platelet cytosolic Ca++ |
Reactome Imported |
Subnetwork: Thrombin-activated activation cascade |
Reactome Imported |
Subnetwork: Thrombin-mediated activation of PARs |
Reactome Imported |
Subnetwork: Tie2 Signaling |
Reactome Imported |
Subnetwork: vWF interaction with collagen |
Reactome Imported |
Influenza Infection |
Reactome Imported |
Subnetwork: Assembly of Viral Components at the Budding Site |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Entry of Influenza Virion into Host Cell via Endocytosis |
Reactome Imported |
Subnetwork: Export of Viral Ribonucleoproteins from Nucleus |
Reactome Imported |
Subnetwork: Fusion and Uncoating of the Influenza Virion |
Reactome Imported |
Subnetwork: Fusion of the Influenza Virion to the Host Cell Endosome |
Reactome Imported |
Subnetwork: Host Interactions with Influenza Factors |
Reactome Imported |
Subnetwork: Influenza Life Cycle |
Reactome Imported |
Subnetwork: Influenza Viral RNA Transcription and Replication |
Reactome Imported |
Subnetwork: Influenza Virus Induced Apoptosis |
Reactome Imported |
Subnetwork: Inhibition of Host mRNA Processing and RNA Silencing |
Reactome Imported |
Subnetwork: Inhibition of IFN-beta |
Reactome Imported |
Subnetwork: Inhibition of Interferon Synthesis |
Reactome Imported |
Subnetwork: Inhibition of PKR |
Reactome Imported |
Subnetwork: NEP/NS2 Interacts with the Cellular Export Machinery |
Reactome Imported |
Subnetwork: NS1 Mediated Effects on Host Pathways |
Reactome Imported |
Subnetwork: Packaging of Eight RNA Segments |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus |
Reactome Imported |
Subnetwork: Transport of Ribonucleoproteins into the Host Nucleus |
Reactome Imported |
Subnetwork: Uncoating of the Influenza Virion |
Reactome Imported |
Subnetwork: Viral Messenger RNA Synthesis |
Reactome Imported |
Subnetwork: Viral RNP Complexes in the Host Cell Nucleus |
Reactome Imported |
Subnetwork: Viral mRNA Translation |
Reactome Imported |
Subnetwork: Virus Assembly and Release |
Reactome Imported |
Subnetwork: cRNA Synthesis |
Reactome Imported |
Subnetwork: vRNA Synthesis |
Reactome Imported |
Subnetwork: vRNP Assembly |
Reactome Imported |
Inhibition of HSL |
Reactome Imported |
Integration of energy metabolism |
Reactome Imported |
Subnetwork: AMPK inhibits chREBP transcriptional activation activity |
Reactome Imported |
Subnetwork: Activated AMPK stimulates fatty-acid oxidation in muscle |
Reactome Imported |
Subnetwork: ChREBP activates metabolic gene expression |
Reactome Imported |
Subnetwork: G(s)-alpha mediated events in glucagon signalling |
Reactome Imported |
Subnetwork: Glucagon signaling in metabolic regulation |
Reactome Imported |
Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix |
Reactome Imported |
Subnetwork: Insulin effects increased synthesis of Xylulose-5-Phosphate |
Reactome Imported |
Subnetwork: PKA activation in glucagon signalling |
Reactome Imported |
Subnetwork: PKA-mediated phosphorylation of key metabolic factors |
Reactome Imported |
Subnetwork: PP2A-mediated dephosphorylation of key metabolic factors |
Reactome Imported |
Subnetwork: Regulation of pyruvate dehydrogenase complex (PDC) |
Reactome Imported |
Integrin cell surface interactions |
Reactome Imported |
Lipid and lipoprotein metabolism |
Reactome Imported |
Subnetwork: Androgen biosynthesis |
Reactome Imported |
Subnetwork: Beta oxidation of butanoyl-CoA to acetyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of hexanoyl-CoA to butanoyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of myristoyl-CoA to lauroyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of octanoyl-CoA to hexanoyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of palmitoyl-CoA to myristoyl-CoA |
Reactome Imported |
Subnetwork: Cholesterol biosynthesis |
Reactome Imported |
Subnetwork: Chylomicron-mediated lipid transport |
Reactome Imported |
Subnetwork: Conversion of Fatty Acyl-CoA to Phosphatidic Acid |
Reactome Imported |
Subnetwork: Conversion of Phosphatidic Acid to Diacylglycerol |
Reactome Imported |
Subnetwork: Digestion of dietary lipid |
Reactome Imported |
Subnetwork: Estrogen biosynthesis |
Reactome Imported |
Subnetwork: Fatty Acyl-CoA Biosynthesis |
Reactome Imported |
Subnetwork: Formation of Acetoacetic Acid |
Reactome Imported |
Subnetwork: Formation of Cytosolic Glycerol-3-phosphate |
Reactome Imported |
Subnetwork: Glucocorticoid biosynthesis |
Reactome Imported |
Subnetwork: HDL-mediated lipid transport |
Reactome Imported |
Subnetwork: Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
Reactome Imported |
Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix |
Reactome Imported |
Subnetwork: Ketone body metabolism |
Reactome Imported |
Subnetwork: LDL endocytosis |
Reactome Imported |
Subnetwork: Lipoprotein metabolism |
Reactome Imported |
Subnetwork: Metabolism of bile acids and bile salts |
Reactome Imported |
Subnetwork: Mineralocorticoid biosynthesis |
Reactome Imported |
Subnetwork: Mitochondrial Fatty Acid Beta-Oxidation |
Reactome Imported |
Subnetwork: Pregnenolone biosynthesis |
Reactome Imported |
Subnetwork: Recycling of bile acids and salts |
Reactome Imported |
Subnetwork: Steroid hormone biosynthesis |
Reactome Imported |
Subnetwork: Steroid metabolism |
Reactome Imported |
Subnetwork: Synthesis of Ketone Bodies |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts via 27-hydroxycholesterol |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
Reactome Imported |
Subnetwork: Synthesis of lysophosphatidic acid from glycerol-3-phosphate |
Reactome Imported |
Subnetwork: Synthesis of phosphatidic acid from lysophosphatidic acid |
Reactome Imported |
Subnetwork: Trafficking of dietary sterols |
Reactome Imported |
Subnetwork: Transformation of lanosterol to cholesterol |
Reactome Imported |
Subnetwork: Triacylglyceride Biosynthesis |
Reactome Imported |
Subnetwork: Utilization of Ketone Bodies |
Reactome Imported |
Subnetwork: mitochondrial fatty acid beta-oxidation of saturated fatty acids |
Reactome Imported |
Subnetwork: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids |
Reactome Imported |
Mal Cascade |
Reactome Imported |
Membrane Trafficking |
Reactome Imported |
Subnetwork: COPI Mediated Transport |
Reactome Imported |
Subnetwork: COPII (Coat Protein 2) Mediated Vesicle Transport |
Reactome Imported |
Subnetwork: ER to Golgi Transport |
Reactome Imported |
Subnetwork: Golgi to ER Retrograde Transport |
Reactome Imported |
Subnetwork: Vamp2 associated Clathrin derived vesicle budding |
Reactome Imported |
Subnetwork: Vamp7 associated clathrin derived vesicle budding |
Reactome Imported |
Subnetwork: Vamp8 associated clathrin derived vesicle budding |
Reactome Imported |
Subnetwork: trans-Golgi Network Vesicle Budding |
Reactome Imported |
Metabolism of amino acids |
Reactome Imported |
Subnetwork: Agmatine biosynthesis |
Reactome Imported |
Subnetwork: Alanine metabolism |
Reactome Imported |
Subnetwork: Amino acid uptake across the plasma membrane |
Reactome Imported |
Subnetwork: Aspartate, asparagine, glutamate, and glutamine metabolism |
Reactome Imported |
Subnetwork: Branched-chain amino acid catabolism |
Reactome Imported |
Subnetwork: Carnitine synthesis |
Reactome Imported |
Subnetwork: Creatine metabolism |
Reactome Imported |
Subnetwork: Histidine catabolism |
Reactome Imported |
Subnetwork: Interconversion of polyamines |
Reactome Imported |
Subnetwork: Isoleucine catabolism |
Reactome Imported |
Subnetwork: Leucine catabolism |
Reactome Imported |
Subnetwork: Lysine catabolism |
Reactome Imported |
Subnetwork: Metabolism of polyamines |
Reactome Imported |
Subnetwork: Ornithine and proline metabolism |
Reactome Imported |
Subnetwork: Ornithine metabolism |
Reactome Imported |
Subnetwork: Oxidative decarboxylation of alpha-keto-beta-methylvalerate to alpha-methylbutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase |
Reactome Imported |
Subnetwork: Oxidative decarboxylation of alpha-ketoadipate to glutaryl CoA by alpha-ketoglutarate dehydrogenase |
Reactome Imported |
Subnetwork: Oxidative decarboxylation of alpha-ketoisocaproate to isovaleryl-CoA by branched-chain alpha-ketoacid dehydrogenase |
Reactome Imported |
Subnetwork: Oxidative decarboxylation of alpha-ketoisovalerate to isobutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase |
Reactome Imported |
Subnetwork: Phenylalanine and tyrosine catabolism |
Reactome Imported |
Subnetwork: Proline catabolism |
Reactome Imported |
Subnetwork: Proline synthesis |
Reactome Imported |
Subnetwork: Regulation of ornithine decarboxylase (ODC) |
Reactome Imported |
Subnetwork: Tryptophan catabolism |
Reactome Imported |
Subnetwork: Urea synthesis |
Reactome Imported |
Subnetwork: Valine catabolism |
Reactome Imported |
Metabolism of carbohydrates |
Reactome Imported |
Subnetwork: (1,6)-alpha-glucose residues are removed, as D-glucose, from limit dextrin by debranching enzyme |
Reactome Imported |
Subnetwork: 1,3-bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP |
Reactome Imported |
Subnetwork: 5-Phosphoribose 1-diphosphate biosynthesis |
Reactome Imported |
Subnetwork: Debranching enzyme transfers 3-glucose blocks from branches in limit dextrin |
Reactome Imported |
Subnetwork: Digestion of dietary carbohydrate |
Reactome Imported |
Subnetwork: Dihydroxyacetone phosphate is isomerized to form glyceraldehyde-3-phosphate |
Reactome Imported |
Subnetwork: Fructose 6-phosphate and ATP react to form fructose 2,6-bisphosphate and ADP |
Reactome Imported |
Subnetwork: Fructose catabolism |
Reactome Imported |
Subnetwork: Galactose catabolism |
Reactome Imported |
Subnetwork: Gluconeogenesis |
Reactome Imported |
Subnetwork: Glucose + ATP => glucose-6-phosphate + ADP |
Reactome Imported |
Subnetwork: Glucose 6-phosphate is isomerized to form fructose-6-phosphate |
Reactome Imported |
Subnetwork: Glucose is carried across the plasma membrane by a glucose transport protein (GLUT) |
Reactome Imported |
Subnetwork: Glucose metabolism |
Reactome Imported |
Subnetwork: Glucose uptake |
Reactome Imported |
Subnetwork: Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+ |
Reactome Imported |
Subnetwork: Glycogen branching enzyme transfers terminal alpha(1,4)glucose blocks to form alpha(1,6) branches |
Reactome Imported |
Subnetwork: Glycogen breakdown (glycogenolysis) |
Reactome Imported |
Subnetwork: Glycogen synthase catalyzes the addition of glucose residues to the non-reducing end of a (1,4)-alpha-D-glucose multimer |
Reactome Imported |
Subnetwork: Glycogen synthesis |
Reactome Imported |
Subnetwork: Glycogen-glycogenin reacts with n orthophosphates, yielding n glucose 1-phosphates and limit dextrin-glycogenin |
Reactome Imported |
Subnetwork: Glycogenin catalyzes the synthesis of an oligo(1,4)glucose moiety covalently attached to itself |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Hexose uptake |
Reactome Imported |
Subnetwork: Negative Regulation of Glucokinase by Glucokinase Regulatory Protein |
Reactome Imported |
Subnetwork: Pentose phosphate pathway (hexose monophosphate shunt) |
Reactome Imported |
Subnetwork: Phosphoenolpyruvate and ADP react to form pyruvate and ATP |
Reactome Imported |
Subnetwork: Phosphorylase kinase activates glycogen phosphorylase |
Reactome Imported |
Subnetwork: Phosphorylated glycogen synthase catalyzes the addition of glucose residues to the non-reducing end of a (1,4)-alpha-D-glucose multimer when activated by glucose-6-phosphate |
Reactome Imported |
Subnetwork: Poly{(1,4)-alpha-glucosyl} glycogenin reacts with n orthophosphates to form glycogenin and n D-glucose 1-phosphates |
Reactome Imported |
Subnetwork: Pyruvate metabolism |
Reactome Imported |
Subnetwork: UTP and glucose 1-phosphate react to form UDP-glucose and pyrophosphate |
Reactome Imported |
Metabolism of nitric oxide |
Reactome Imported |
Subnetwork: NOSIP mediated eNOS trafficking |
Reactome Imported |
Subnetwork: NOSTRIN mediated eNOS trafficking |
Reactome Imported |
Subnetwork: eNOS activation |
Reactome Imported |
Subnetwork: eNOS activation and regulation |
Reactome Imported |
Subnetwork: eNOS acylation cycle |
Reactome Imported |
Metabolism of non-coding RNA |
Reactome Imported |
Subnetwork: snRNP Assembly |
Reactome Imported |
Metabolism of vitamins and cofactors |
Reactome Imported |
Subnetwork: Biotin metabolism |
Reactome Imported |
Subnetwork: Coenzyme A biosynthesis |
Reactome Imported |
Subnetwork: Metabolism of folate and pterines |
Reactome Imported |
Subnetwork: Metabolism of water-soluble vitamins and cofactors |
Reactome Imported |
Subnetwork: Nicotinamide salvaging |
Reactome Imported |
Subnetwork: Nicotinate metabolism |
Reactome Imported |
Subnetwork: Vitamin B1 (thiamin) metabolism |
Reactome Imported |
Subnetwork: Vitamin B2 (riboflavin) metabolism |
Reactome Imported |
Subnetwork: Vitamin B5 (pantothenate) metabolism |
Reactome Imported |
Subnetwork: Vitamin C (ascorbate) metabolism |
Reactome Imported |
Mitochondrial Uncoupling Proteins |
Reactome Imported |
Subnetwork: The fatty acid cycling model |
Reactome Imported |
Subnetwork: The proton buffering model |
Reactome Imported |
Nucleotide metabolism |
Reactome Imported |
Subnetwork: ATP formation |
Reactome Imported |
Subnetwork: Conversion of cytosolic inosine 5'-monophosphate (IMP), NAD+, and H2O to xanthosine 5'-monophosphate (XMP) and NADH + H+ |
Reactome Imported |
Subnetwork: Conversion of cytosolic inosine 5'-monophosphate, L-aspartate, and GTP to adenylosuccinate, guanosine 5'-diphosphate, and orthophosphate |
Reactome Imported |
Subnetwork: De novo synthesis of IMP |
Reactome Imported |
Subnetwork: De novo synthesis of the pyrimidine ring and conversion to UMP |
Reactome Imported |
Subnetwork: Deoxyribonucleotide salvage |
Reactome Imported |
Subnetwork: Formation of ATP by chemiosmotic coupling |
Reactome Imported |
Subnetwork: Guanine formation |
Reactome Imported |
Subnetwork: Hydrolysis of cytosolic nucleoside 5'- and 3'-monophosphates by 5',3'-nucleotidase, cytosolic |
Reactome Imported |
Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase cytosolic IA |
Reactome Imported |
Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase cytosolic IB |
Reactome Imported |
Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase cytosolic II |
Reactome Imported |
Subnetwork: Hydrolysis of cytosolic nucleoside 5'-monophosphates by 5'-nucleotidase, cytosolic III |
Reactome Imported |
Subnetwork: Hydrolysis of extracellular nucleoside 5'-monophosphates by plasma membrane-bound 5'-nucleotidase |
Reactome Imported |
Subnetwork: Hydrolysis of mitochondrial nucleoside 5'- and 3'-monophosphates by 5',3'-nucleotidase, mitochondrial |
Reactome Imported |
Subnetwork: Hydrolysis of nucleoside 5'-monophosphates to nucleosides plus orthophosphate |
Reactome Imported |
Subnetwork: Hypoxanthine formation |
Reactome Imported |
Subnetwork: Inosine formation |
Reactome Imported |
Subnetwork: Phosphorylation of cytosolic nucleosides by adenosine kinase |
Reactome Imported |
Subnetwork: Phosphorylation of cytosolic nucleosides by deoxycytidine kinase |
Reactome Imported |
Subnetwork: Phosphorylation of cytosolic nucleosides by thymidine kinase 1, soluble |
Reactome Imported |
Subnetwork: Phosphorylation of cytosolic nucleosides by uridine-cytidine kinase 1 |
Reactome Imported |
Subnetwork: Phosphorylation of cytosolic nucleosides by uridine-cytidine kinase 2 |
Reactome Imported |
Subnetwork: Phosphorylation of mitochondrial nucleosides by deoxyguanosine kinase |
Reactome Imported |
Subnetwork: Phosphorylation of mitochondrial nucleosides by thymidine kinase 2, mitochondrial |
Reactome Imported |
Subnetwork: Phosphorylation of nucleosides to form nucleoside 5'-monophosphates |
Reactome Imported |
Subnetwork: Purine biosynthesis |
Reactome Imported |
Subnetwork: Purine catabolism |
Reactome Imported |
Subnetwork: Purine metabolism |
Reactome Imported |
Subnetwork: Purine salvage reactions |
Reactome Imported |
Subnetwork: Pyrimidine biosynthesis (interconversion) |
Reactome Imported |
Subnetwork: Pyrimidine catabolism |
Reactome Imported |
Subnetwork: Pyrimidine metabolism |
Reactome Imported |
Subnetwork: Pyrimidine salvage reactions |
Reactome Imported |
Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (glutaredoxin) |
Reactome Imported |
Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin) |
Reactome Imported |
Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and glutaredoxin |
Reactome Imported |
Subnetwork: Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin |
Reactome Imported |
Subnetwork: Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin) |
Reactome Imported |
Subnetwork: Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin |
Reactome Imported |
Subnetwork: Reversible phosphorolysis of pyrimidine nucleosides |
Reactome Imported |
Subnetwork: Reversible phosphorolysis of pyrimidine nucleosides by thymidine phosphorylase |
Reactome Imported |
Subnetwork: Reversible phosphorolysis of pyrimidine nucleosides by uridine phosphorylase 1 |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A hexamer |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A,B heterohexamer |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase B hexamer |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase C hexamer |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by UMP-CMP kinase |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by adenylate kinase 1 |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by adenylate kinase 5 |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by deoxythymidylate kinase (thymidylate kinase) |
Reactome Imported |
Subnetwork: Reversible phosphorylation of cytosolic nucleoside monophosphates by guanylate kinase 1 |
Reactome Imported |
Subnetwork: Reversible phosphorylation of mitochondrial nucleoside diphosphates by nucleoside diphosphate kinase D, mitochondrial hexamer |
Reactome Imported |
Subnetwork: Reversible phosphorylation of mitochondrial nucleoside monophosphates by adenylate kinase 2 |
Reactome Imported |
Subnetwork: Reversible phosphorylation of nucleoside diphosphates |
Reactome Imported |
Subnetwork: Reversible phosphorylation of nucleoside monophosphates |
Reactome Imported |
Subnetwork: Ribonucleotide salvage |
Reactome Imported |
Subnetwork: Synthesis of deoxyribonucleoside 5'-diphosphates from ribonucleoside 5'-diphosphates |
Reactome Imported |
Subnetwork: Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane |
Reactome Imported |
Subnetwork: Xanthine formation |
Reactome Imported |
Subnetwork: dATP formation |
Reactome Imported |
Subnetwork: dGTP formation |
Reactome Imported |
Pausing and recovery of HIV-1 elongation |
Reactome Imported |
Pausing and recovery of Tat-mediated HIV-1 elongation |
Reactome Imported |
Pausing and recovery of elongation |
Reactome Imported |
Phase 1 functionalization |
Reactome Imported |
Subnetwork: Amine Oxidase reactions |
Reactome Imported |
Subnetwork: COX reactions |
Reactome Imported |
Subnetwork: Cytochrome p450 |
Reactome Imported |
Subnetwork: Ester hydrolysis |
Reactome Imported |
Subnetwork: FMO reactions |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 |
Reactome Imported |
Subnetwork: N-oxidation of nitrogen compounds |
Reactome Imported |
Subnetwork: P450 Dehalogenation |
Reactome Imported |
Subnetwork: P450 Dehydrogenation of alkanes to form alkenes |
Reactome Imported |
Subnetwork: P450 Epoxidations |
Reactome Imported |
Subnetwork: P450 Hydroxylations |
Reactome Imported |
Subnetwork: P450 Prostaglandin isomerizations |
Reactome Imported |
Subnetwork: P450 oxidation |
Reactome Imported |
Subnetwork: Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs |
Reactome Imported |
Subnetwork: Simple hydroxylation |
Reactome Imported |
Porphyrin metabolism |
Reactome Imported |
Subnetwork: Heme biosynthesis |
Reactome Imported |
Post-translational protein modification |
Reactome Imported |
Subnetwork: Attachment of GPI anchor to uPAR |
Reactome Imported |
Subnetwork: Gamma-carboxylation of protein precursors |
Reactome Imported |
Subnetwork: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
Reactome Imported |
Subnetwork: Hypusine synthesis from eIF5A-lysine |
Reactome Imported |
Subnetwork: Removal of aminoterminal propeptides from gamma-carboxylated proteins |
Reactome Imported |
Subnetwork: Synthesis of GPI-anchored proteins |
Reactome Imported |
Subnetwork: Synthesis of dolichol-phosphate mannose |
Reactome Imported |
Subnetwork: Synthesis of glycosylphosphatidylinositol (GPI) |
Reactome Imported |
Subnetwork: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus |
Reactome Imported |
Propionyl-CoA catabolism |
Reactome Imported |
Pyruvate metabolism and TCA cycle |
Reactome Imported |
Subnetwork: Citric acid cycle (TCA cycle) |
Reactome Imported |
Subnetwork: Pyruvate metabolism |
Reactome Imported |
Regulation of activated PAK-2p34 by proteasome mediated degradation |
Reactome Imported |
Regulation of beta-cell development |
Reactome Imported |
Subnetwork: AKT-mediated inactivation of FOXO1A |
Reactome Imported |
Subnetwork: Regulation of gene expression in beta cells |
Reactome Imported |
Regulatory RNA pathways |
Reactome Imported |
Subnetwork: MicroRNA biogenesis |
Reactome Imported |
Signal attenuation |
Reactome Imported |
Signaling by TGF beta |
Reactome Imported |
Signaling by BMP |
Reactome Imported |
Signaling by EGFR |
Reactome Imported |
Subnetwork: EGFR downregulation |
Reactome Imported |
Subnetwork: EGFR interacts with phospholipase C-gamma |
Reactome Imported |
Subnetwork: Gab1 signalosome |
Reactome Imported |
Subnetwork: Grb2 events in EGFR signaling |
Reactome Imported |
Subnetwork: Shc events in EGFR signaling |
Reactome Imported |
Signaling by FGFR |
Reactome Imported |
Subnetwork: FGFR ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1 ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1b ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1c and Klotho ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1c ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR2 ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR2b ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR2c ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR3 ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR3b ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR3c ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR4 ligand binding and activation |
Reactome Imported |
Signaling by GPCR |
Reactome Imported |
Subnetwork: Class A/1 (Rhodopsin-like receptors) |
Reactome Imported |
Subnetwork: Peptide ligand-binding receptors |
Reactome Imported |
Signaling by Insulin receptor |
Reactome Imported |
Subnetwork: Activation of PKB |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: IRS activation |
Reactome Imported |
Subnetwork: IRS-mediated signalling |
Reactome Imported |
Subnetwork: IRS-related events |
Reactome Imported |
Subnetwork: Inhibition of TSC complex formation by PKB |
Reactome Imported |
Subnetwork: Insulin receptor recycling |
Reactome Imported |
Subnetwork: Insulin receptor signalling cascade |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: PDE3B signalling |
Reactome Imported |
|
Reactome Imported |
Subnetwork: PKB-mediated events |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Subnetwork: Release of eIF4E |
Reactome Imported |
Subnetwork: S6K1 signalling |
Reactome Imported |
Subnetwork: S6K1-mediated signalling |
Reactome Imported |
Subnetwork: SHC activation |
Reactome Imported |
Subnetwork: SHC-mediated signalling |
Reactome Imported |
Subnetwork: SHC-related events |
Reactome Imported |
Subnetwork: SOS-mediated signalling |
Reactome Imported |
Subnetwork: mTOR signalling |
Reactome Imported |
Subnetwork: mTORC1-mediated signalling |
Reactome Imported |
Signaling by Notch |
Reactome Imported |
Subnetwork: A third proteolytic cleavage releases NICD |
Reactome Imported |
Subnetwork: Maturation of Notch precursor via proteolytic cleavage |
Reactome Imported |
Subnetwork: Mature Notch receptor trafficks to plasma membrane |
Reactome Imported |
Subnetwork: NICD trafficks to nucleus |
Reactome Imported |
Subnetwork: Notch receptor binds with a ligand |
Reactome Imported |
Subnetwork: Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
Reactome Imported |
Subnetwork: Transport of Notch receptor precursor to golgi |
Reactome Imported |
Signaling by Rho GTPases |
Reactome Imported |
Subnetwork: Rho GTPase cycle |
Reactome Imported |
Signaling by VEGF |
Reactome Imported |
Subnetwork: Neurophilin interactions with VEGF and VEGFR |
Reactome Imported |
Subnetwork: VEGF binds to VEGFR leading to receptor dimerization |
Reactome Imported |
Subnetwork: VEGF ligand-receptor interactions |
Reactome Imported |
Signaling by Wnt |
Reactome Imported |
Subnetwork: Beta-catenin phosphorylation cascade |
Reactome Imported |
Subnetwork: Degradation of beta-catenin by the destruction complex |
Reactome Imported |
Signaling in Immune system |
Reactome Imported |
Subnetwork: Activated TLR4 signalling |
Reactome Imported |
Subnetwork: Activation of C3 and C5 |
Reactome Imported |
Subnetwork: Alternative complement activation |
Reactome Imported |
Subnetwork: Basigin interactions |
Reactome Imported |
Subnetwork: Cell surface interactions at the vascular wall |
Reactome Imported |
Subnetwork: Classical antibody-mediated complement activation |
Reactome Imported |
Subnetwork: Complement cascade |
Reactome Imported |
Subnetwork: Creation of C4 and C2 activators |
Reactome Imported |
Subnetwork: Downstream TCR signaling |
Reactome Imported |
Subnetwork: Generation of second messenger molecules |
Reactome Imported |
Subnetwork: Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
Reactome Imported |
Subnetwork: Initial triggering of complement |
Reactome Imported |
Subnetwork: Innate Immunity Signaling |
Reactome Imported |
Subnetwork: LPS transferred from LBP carrier to CD14 |
Reactome Imported |
Subnetwork: Lectin pathway of complement activation |
Reactome Imported |
Subnetwork: MyD88 cascade |
Reactome Imported |
Subnetwork: PECAM1 interactions |
Reactome Imported |
Subnetwork: Phosphorylation of CD3 and TCR zeta chains |
Reactome Imported |
Subnetwork: TCR signaling |
Reactome Imported |
Subnetwork: TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Terminal pathway of complement |
Reactome Imported |
Subnetwork: Tie2 Signaling |
Reactome Imported |
Subnetwork: Toll Like Receptor 10 (TLR10) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 2 Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 3 (TLR3) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 4 (TLR4) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 5 (TLR5) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 7/8 (TLR7/8) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 9 (TLR9) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor TLR1:TLR2 Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor TLR6:TLR2 Cascade |
Reactome Imported |
Subnetwork: Toll Receptor Cascades |
Reactome Imported |
Subnetwork: Translocation of ZAP-70 to Immunological synapse |
Reactome Imported |
Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates RIP1 |
Reactome Imported |
Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates TBK1 |
Reactome Imported |
Signalling by NGF |
Reactome Imported |
Subnetwork: AKT phosphorylates targets in the cytosol |
Reactome Imported |
Subnetwork: AKT phosphorylates targets in the nucleus |
Reactome Imported |
Subnetwork: ARMS-mediated activation |
Reactome Imported |
Subnetwork: Activation of TRKA receptors |
Reactome Imported |
Subnetwork: Axonal growth inhibition (RHOA activation) |
Reactome Imported |
Subnetwork: Axonal growth stimulation |
Reactome Imported |
Subnetwork: CREB phosphorylation |
Reactome Imported |
Subnetwork: Cell death signalling via NRAGE, NRIF and NADE |
Reactome Imported |
Subnetwork: Ceramide signalling |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK/MAPK targets |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: ERKs are inactivated |
Reactome Imported |
Subnetwork: Frs2-mediated activation |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: NADE modulates death signalling |
Reactome Imported |
Subnetwork: NF-kB is activated and signals survival |
Reactome Imported |
Subnetwork: NFG and proNGF binds to p75NTR |
Reactome Imported |
Subnetwork: NGF processing |
Reactome Imported |
Subnetwork: NGF-independant TRKA activation |
Reactome Imported |
Subnetwork: NRAGE signals death through JNK |
Reactome Imported |
Subnetwork: NRIF signals cell death from the nucleus |
Reactome Imported |
Subnetwork: Negative regulation of the PI3K/AKT network |
Reactome Imported |
Subnetwork: Nuclear Events (kinase and transcription factor activation) |
Reactome Imported |
Subnetwork: PI3K/AKT signalling |
Reactome Imported |
Subnetwork: PLC-gamma1 signalling |
Reactome Imported |
Subnetwork: Prolonged ERK activation events |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Subnetwork: Regulated proteolysis of p75NTR |
Reactome Imported |
Subnetwork: Retrograde neurotrophin signalling |
Reactome Imported |
Subnetwork: Signalling to ERK5 |
Reactome Imported |
Subnetwork: Signalling to ERKs |
Reactome Imported |
Subnetwork: Signalling to RAS |
Reactome Imported |
Subnetwork: Signalling to STAT3 |
Reactome Imported |
Subnetwork: Signalling to p38 via RIT and RIN |
Reactome Imported |
Subnetwork: TRKA activation by NGF |
Reactome Imported |
Subnetwork: TRKA signalling from the plasma membrane |
Reactome Imported |
Subnetwork: p38MAPK events |
Reactome Imported |
Subnetwork: p75 NTR receptor-mediated signalling |
Reactome Imported |
Subnetwork: p75NTR negatively regulates cell cycle via SC1 |
Reactome Imported |
Subnetwork: p75NTR recruits signalling complexes |
Reactome Imported |
Subnetwork: p75NTR regulates axonogenesis |
Reactome Imported |
Subnetwork: p75NTR signals via NF-kB |
Reactome Imported |
Synaptic Transmission |
Reactome Imported |
Subnetwork: Astrocytic Glutamate-Glutamine Uptake And Metabolism |
Reactome Imported |
Subnetwork: Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels |
Reactome Imported |
Subnetwork: Glutamate Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Neurotransmitter Clearance In The Synaptic Cleft |
Reactome Imported |
Subnetwork: Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Neurotransmitter uptake and Metabolism In Glial Cells |
Reactome Imported |
Subnetwork: Transmission across Chemical Synapses |
Reactome Imported |
Synthesis of lysophosphatidic acid from dihydroxyacetone phosphate |
Reactome Imported |
Tat-mediated HIV-1 elongation arrest and recovery |
Reactome Imported |
Telomere Maintenance |
Reactome Imported |
Subnetwork: Extension of Telomeres |
Reactome Imported |
Subnetwork: Packaging Of Telomere Ends |
Reactome Imported |
Subnetwork: Polymerase switching on the C-strand of the telomere |
Reactome Imported |
Subnetwork: Processive synthesis on the C-strand of the telomere |
Reactome Imported |
Subnetwork: Removal of the Flap Intermediate from the C-strand |
Reactome Imported |
Subnetwork: Telomere C-strand (Lagging Strand) Synthesis |
Reactome Imported |
Subnetwork: Telomere C-strand synthesis initiation |
Reactome Imported |
Subnetwork: Telomere Extension By Telomerase |
Reactome Imported |
Transcription |
Reactome Imported |
Subnetwork: Cleavage of Growing Transcript in the Termination Region |
Reactome Imported |
Subnetwork: Formation of RNA Pol II elongation complex |
Reactome Imported |
Subnetwork: Formation of the Early Elongation Complex |
Reactome Imported |
Subnetwork: Mitochondrial transcription initiation |
Reactome Imported |
Subnetwork: Mitochondrial transcription termination |
Reactome Imported |
Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE |
Reactome Imported |
Subnetwork: RNA Polymerase I Chain Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase I Promoter Clearance |
Reactome Imported |
Subnetwork: RNA Polymerase I Promoter Escape |
Reactome Imported |
Subnetwork: RNA Polymerase I Promoter Opening |
Reactome Imported |
Subnetwork: RNA Polymerase I Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase I Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase I Transcription Termination |
Reactome Imported |
Subnetwork: RNA Polymerase II Promoter Escape |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Pre-Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Termination |
Reactome Imported |
Subnetwork: RNA Polymerase III Chain Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation From Type 1 Promoter |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation From Type 2 Promoter |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation From Type 3 Promoter |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Termination |
Reactome Imported |
Subnetwork: Transcription from mitochondrial promoters |
Reactome Imported |
Vitamin D (calciferol) metabolism |
Reactome Imported |
mRNA Processing |
Reactome Imported |
Subnetwork: C6 deamination of adenosine |
Reactome Imported |
Subnetwork: Formation of editosomes by ADAR proteins |
Reactome Imported |
Subnetwork: Formation of the Editosome |
Reactome Imported |
Subnetwork: Processing of Capped Intron-Containing Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped Intronless Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Intronless Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP independent Processing of Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: Transport of Mature Transcript to Cytoplasm |
Reactome Imported |
Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts |
Reactome Imported |
Subnetwork: Transport of the SLBP Dependant Mature mRNA |
Reactome Imported |
Subnetwork: Transport of the SLBP independent Mature mRNA |
Reactome Imported |
Subnetwork: mRNA 3'-end processing |
Reactome Imported |
|
Reactome Imported |
|
Reactome Imported |
Subnetwork: mRNA Editing: A to I Conversion |
Reactome Imported |
Subnetwork: mRNA Editing: C to U Conversion |
Reactome Imported |
Subnetwork: mRNA Splicing |
Reactome Imported |
Subnetwork: mRNA Splicing - Major Pathway |
Reactome Imported |
Subnetwork: mRNA Splicing - Minor Pathway |
Reactome Imported |