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Overview
The Molecular Libraries Program (MLP; an NIH Roadmap Initiative) aims to enhance chemical biology efforts through High Throughput Screening (HTS) to obtain small molecule probes effective at modulating a given biological process or disease state. More …
Molecular Libraries Probe Production Centers (MLPCN)
The flagship of the MLP is the Molecular Libraries Probe Production Centers, a network of national laboratories, whose aim is generate novel small molecule probes by performing HTS, secondary screens and medicinal chemistry. The assays for these probes are sourced from the scientific community.
- Accessing the MLPCN
- The scientific community can access the resources of the MLPCN through various funding initiatives that are part of the MLP. More …
- Small Molecule Probes
- The small molecule probes already identified in the pilot phase of the MLP can be found here.
- Access To Results
- The MLPCN (as well as the pilot phase initiative) is a public resource and as such all the biological data generated as well as the identity of the small molecules (300,000+ compounds) is in the public domain. More …
- The Centers
- Find details about the MLPCN centers here.
Other Supporting MLP Initiatives
The Molecular Libraries Program has other initiatives intended to further develop chemical biology. These initiatives are focused on technology development and contain future funding information. More …
Further Development of Small Molecule Probes
NIH has many pre-existing and new efforts to further develop small molecule probes resulting from the MLPCN effort. More …
Frequently Asked Questions
More details on the Molecular Libraries program including a FAQ are available on this website and can be accessed using the menus on top.
