| | Research Articles A Randomized Trial Evaluating Prosaptide™ for HIV-Associated Sensory Neuropathies: Use of an Electronic Diary to Record Neuropathic Pain Scott R. Evans, David M. Simpson, Douglas W. Kitch, Agnes King, David B. Clifford, Bruce A. Cohen, Justin C. McArthur, and for the Neurologic AIDS Research Consortium and the AIDS Clinical Trials Group PMCID: PMC1919427 Locating Pleistocene Refugia: Comparing Phylogeographic and Ecological Niche Model Predictions Eric Waltari, Robert J. Hijmans, A. Townsend Peterson, Árpád S. Nyári, Susan L. Perkins, and Robert P. Guralnick PMCID: PMC1905943 Therapeutic Strategy for Acute Spinal Cord Contusion Injury: Cell Elimination Combined with Microsurgical Intervention Nurit Kalderon, Manickam Muruganandham, Jason A. Koutcher, and Melissa Potuzak PMCID: PMC1914062 Protein-Tyrosine Kinase Activity Profiling in Knock Down Zebrafish Embryos Simone Lemeer, Chris Jopling, Faris Naji, Rob Ruijtenbeek, Monique Slijper, Albert J.R. Heck, and Jeroen den Hertog PMCID: PMC1895888 Genetic Diversity among Enterococcus faecalis Shonna M. McBride, Vincent A. Fischetti, Donald J. LeBlanc, Robert C. Moellering, Jr., and Michael S. Gilmore PMCID: PMC1899230 Immunodominance of Lytic Cycle Antigens in Epstein-Barr Virus-Specific CD4+ T Cell Preparations for Therapy Dinesh Adhikary, Uta Behrends, Heike Boerschmann, Andrea Pfünder, Stefan Burdach, Andreas Moosmann, Klaus Witter, Georg W. Bornkamm, and Josef Mautner PMCID: PMC1894652 A Novel Unsupervised Method to Identify Genes Important in the Anti-viral Response: Application to Interferon/Ribavirin in Hepatitis C Patients Leonid I. Brodsky, Abdus S. Wahed, Jia Li, John E. Tavis, Takuma Tsukahara, and Milton W. Taylor PMCID: PMC1978073 Lymphocytes and the Dap12 Adaptor Are Key Regulators of Osteoclast Activation Associated with Gonadal Failure Adrienne Anginot, Romain Dacquin, Marlène Mazzorana, and Pierre Jurdic PMCID: PMC1899087 Bone Microenvironment Specific Roles of ITAM Adapter Signaling during Bone Remodeling Induced by Acute Estrogen-Deficiency Yalei Wu, James Torchia, Wei Yao, Nancy E. Lane, Lewis L. Lanier, Mary C. Nakamura, and Mary Beth Humphrey PMCID: PMC1895921 The Circadian System Is a Target and Modulator of Prenatal Cocaine Effects Eva H. Shang and Irina V. Zhdanova PMCID: PMC1899232 Long-Term Impact of Radiation on the Stem Cell and Oligodendrocyte Precursors in the Brain Georgia Panagiotakos, George Alshamy, Bill Chan, Rory Abrams, Edward Greenberg, Amit Saxena, Michelle Bradbury, Mark Edgar, Philip Gutin, and Viviane Tabar PMCID: PMC1913551 Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons Ilja Mikenberg, Darius Widera, Aljoscha Kaus, Barbara Kaltschmidt, and Christian Kaltschmidt PMCID: PMC1899224 Super-Genotype: Global Monoclonality Defies the Odds of Nature Johannes J. Le Roux, Ania M. Wieczorek, Mark G. Wright, and Carol T. Tran PMCID: PMC1895887 Leveraging Hierarchical Population Structure in Discrete Association Studies Jonathan Carlson, Carl Kadie, Simon Mallal, and David Heckerman PMCID: PMC1899226 ASSET (Age/Sex Standardised Estimates of Treatment): A Research Model to Improve the Governance of Prescribing Funds in Italy Giampiero Favato, Paolo Mariani, Roger W. Mills, Alessandro Capone, Matteo Pelagatti, Vasco Pieri, Alberico Marcobelli, Maria G. Trotta, Alberto Zucchi, and Alberico L. Catapano PMCID: PMC1899227 The Durability of Public Goods Changes the Dynamics and Nature of Social Dilemmas Sam P. Brown and François Taddei PMCID: PMC1899228 Comprehensive Expression Profiling of Tumor Cell Lines Identifies Molecular Signatures of Melanoma Progression Byungwoo Ryu, Dave S. Kim, Amena M. DeLuca, and Rhoda M. Alani PMCID: PMC1895889 Inflammatory Multiple-Sclerosis Plaques Generate Characteristic Metabolic Profiles in Cerebrospinal Fluid Norbert W. Lutz, Angèle Viola, Irina Malikova, Sylviane Confort-Gouny, Bertrand Audoin, Jean-Philippe Ranjeva, Jean Pelletier, and Patrick J. Cozzone PMCID: PMC1899231 The Flavonoid Luteolin Worsens Chemical-Induced Colitis in NF-κBEGFP Transgenic Mice through Blockade of NF-κB-Dependent Protective Molecules Thomas Karrasch, Joo-Sung Kim, Byung Ik Jang, and Christian Jobin PMCID: PMC1895919 Mapping Human Whole-Brain Structural Networks with Diffusion MRI Patric Hagmann, Maciej Kurant, Xavier Gigandet, Patrick Thiran, Van J. Wedeen, Reto Meuli, and Jean-Philippe Thiran PMCID: PMC1895920 Treatment of Fabry Disease: Outcome of a Comparative Trial with Agalsidase Alfa or Beta at a Dose of 0.2 mg/kg Anouk C. Vedder, Gabor E. Linthorst, Gunnar Houge, Johannna E.M. Groener, Els E. Ormel, Berto J. Bouma, Johannes M.F.G. Aerts, Asle Hirth, and Carla E.M. Hollak PMCID: PMC1913555 The Importance of Poisoning vs. Road Traffic Injuries as a Cause of Death in Rural Sri Lanka Michael Eddleston, Nilantha Udayakumara, Sriyantha Adhikari, Dhamika de Silva, M. H. Rezvi Sheriff, and Dhananjaya L. Waidyaratne PMCID: PMC1904253 High Susceptibility of Bt Maize to Aphids Enhances the Performance of Parasitoids of Lepidopteran Pests Cristina A. Faria, Felix L. Wäckers, Jeremy Pritchard, David A. Barrett, and Ted C.J. Turlings PMCID: PMC1899225 Genetic Variation for Cardiac Dysfunction in Drosophila Karen A. Ocorr, Timothy Crawley, Greg Gibson, and Rolf Bodmer PMCID: PMC1913553 Robustness and Stability of the Gene Regulatory Network Involved in DV Boundary Formation in the Drosophila Wing Javier Buceta, Héctor Herranz, Oriol Canela-Xandri, Ramon Reigada, Francesc Sagués, and Marco Milán PMCID: PMC1904254 A Structural Split in the Human Genome Clara S.M. Tang and Richard J. Epstein PMCID: PMC1904255 Visual Stimulation Activates ERK in Synaptic and Somatic Compartments of Rat Cortical Neurons with Parallel Kinetics Elena M. Boggio, Elena Putignano, Marco Sassoè-Pognetto, Tommaso Pizzorusso, and Maurizio Giustetto PMCID: PMC1899229 Loss of Robustness and Addiction to IGF1 during Early Keratinocyte Transformation by Human Papilloma Virus 16 Tamar Geiger and Alexander Levitzki PMCID: PMC1904256 Natural Selection on Female Life-History Traits in Relation to Socio-Economic Class in Pre-Industrial Human Populations Jenni E. Pettay, Samuli Helle, Jukka Jokela, and Virpi Lummaa PMCID: PMC1904257 X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates Christopher L. Reyes, Earl Rutenber, Peter Walter, and Robert M. Stroud PMCID: PMC1904258 Efficient and Specific Internal Cleavage of a Retroviral Palindromic DNA Sequence by Tetrameric HIV-1 Integrase Olivier Delelis, Vincent Parissi, Hervé Leh, Gladys Mbemba, Caroline Petit, Pierre Sonigo, Eric Deprez, and Jean-François Mouscadet PMCID: PMC1905944 Molecular Evolution and Functional Divergence of the Ca2+ Sensor Protein in Store-operated Ca2+ Entry: Stromal Interaction Molecule Xinjiang Cai PMCID: PMC1904252 MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis? Enikö Sonkoly, Tianling Wei, Peter C.J. Janson, Annika Sääf, Lena Lundeberg, Maria Tengvall-Linder, Gunnar Norstedt, Harri Alenius, Bernhard Homey, Annika Scheynius, Mona Ståhle, and Andor Pivarcsi PMCID: PMC1905940 Imitation as Faithful Copying of a Novel Technique in Marmoset Monkeys Bernhard Voelkl and Ludwig Huber PMCID: PMC1905941 Neuronal Conduction of Excitation without Action Potentials Based on Ceramide Production Caroline Fasano, François Tercé, Jean-Pierre Niel, Hang Thi Thu Nguyen, Abel Hiol, Justine Bertrand-Michel, Nicole Mallet, Xavier Collet, and Jean-Pierre Miolan PMCID: PMC1906860 “Sexual” Population Structure and Genetics of the Malaria Agent P. falciparum Themba Mzilahowa, Philip J. McCall, and Ian M. Hastings PMCID: PMC1910609 Climate Change, Genetics or Human Choice: Why Were the Shells of Mankind's Earliest Ornament Larger in the Pleistocene Than in the Holocene? Peter R. Teske, Isabelle Papadopoulos, Christopher D. McQuaid, Brent K. Newman, and Nigel P. Barker PMCID: PMC1913204 Inhibition of Proliferation by PERK Regulates Mammary Acinar Morphogenesis and Tumor Formation Sharon J. Sequeira, Aparna C. Ranganathan, Alejandro P. Adam, Bibiana V. Iglesias, Eduardo F. Farias, and Julio A. Aguirre-Ghiso PMCID: PMC1910610 The Role of Rab3a in Secretory Vesicle Docking Requires Association/Dissociation of Guanidine Phosphates and Munc18-1 Jan R.T. van Weering, Ruud F. Toonen, and Matthijs Verhage PMCID: PMC1910611 Modeling Insertional Mutagenesis Using Gene Length and Expression in Murine Embryonic Stem Cells Alex S. Nord, Karen Vranizan, Whittemore Tingley, Alexander C. Zambon, Kristina Hanspers, Loren G. Fong, Yan Hu, Peter Bacchetti, Thomas E. Ferrin, Patricia C. Babbitt, Scott W. Doniger, William C. Skarnes, Stephen G. Young, and Bruce R. Conklin PMCID: PMC1910612 Assembly of Microtubules and Actomyosin Rings in the Absence of Nuclei and Spindle Pole Bodies Revealed by a Novel Genetic Method Yinyi Huang, P.T. Tran, Snezhana Oliferenko, and Mohan K. Balasubramanian PMCID: PMC1913206 Cortical Modulations Increase in Early Sessions with Brain-Machine Interface Miriam Zacksenhouse, Mikhail A. Lebedev, Jose M. Carmena, Joseph E. O'Doherty, Craig Henriquez, and Miguel A.L. Nicolelis PMCID: PMC1919433 A National Survey of Teachers on Antiretroviral Therapy in Malawi: Access, Retention in Therapy and Survival Simon D. Makombe, Andreas Jahn, Hannock Tweya, Stuart Chuka, Joseph Kwong-Leung Yu, Mindy Hochgesang, John Aberle-Grasse, Lameck Thambo, Erik J. Schouten, Kelita Kamoto, and Anthony D. Harries PMCID: PMC1905945 Primate TNF Promoters Reveal Markers of Phylogeny and Evolution of Innate Immunity Andres Baena, Alan R. Mootnick, James V. Falvo, Alla V. Tsytsykova, Filipa Ligeiro, Ousmane M. Diop, Claudia Brieva, Pascal Gagneux, Stephen J. O'Brien, Oliver A. Ryder, and Anne E. Goldfeld PMCID: PMC1905939 Sequence Polymorphisms Cause Many False cis eQTLs Rudi Alberts, Peter Terpstra, Yang Li, Rainer Breitling, Jan-Peter Nap, and Ritsert C. Jansen PMCID: PMC1906859 Simultaneous Activation of Complement and Coagulation by MBL-Associated Serine Protease 2 Anders Krarup, Russell Wallis, Julia S. Presanis, Péter Gál, and Robert B. Sim PMCID: PMC1910608 The Population Dynamical Implications of Male-Biased Parasitism in Different Mating Systems Martin R. Miller, Andrew White, Kenneth Wilson, and Michael Boots PMCID: PMC1913202 Three-Dimensional Modeling of Glucose-6-phosphate Dehydrogenase-Deficient Variants from German Ancestry Farooq Kiani, Sonja Schwarzl, Stefan Fischer, and Thomas Efferth PMCID: PMC1913203 Do You See What I Mean? Corticospinal Excitability During Observation of Culture-Specific Gestures Istvan Molnar-Szakacs, Allan D. Wu, Francisco J. Robles, and Marco Iacoboni PMCID: PMC1913205 Computational Investigations into the Origins of Short-Term Biochemical Memory in T cell Activation Jason W. Locasale PMCID: PMC1905942 Optimization of Energy-Consuming Pathways towards Rapid Growth in HPV-Transformed Cells Sarit Mizrachy-Schwartz, Nataly Kravchenko-Balasha, Hannah Ben-Bassat, Shoshana Klein, and Alexander Levitzki PMCID: PMC1913554 Formaldehyde at Low Concentration Induces Protein Tau into Globular Amyloid-Like Aggregates In Vitro and In Vivo Chun Lai Nie, Yan Wei, Xinyong Chen, Yan Ying Liu, Wen Dui, Ying Liu, Martyn C. Davies, Saul J.B. Tendler, and Rong Giao He PMCID: PMC1913207 Intergenic Transcription, Cell-Cycle and the Developmentally Regulated Epigenetic Profile of the Human Beta-Globin Locus Joanne Miles, Jennifer A. Mitchell, Lyubomira Chakalova, Beatriz Goyenechea, Cameron S. Osborne, Laura O'Neill, Keiji Tanimoto, James Douglas Engel, and Peter Fraser PMCID: PMC1910613 Brucella abortus Uses a Stealthy Strategy to Avoid Activation of the Innate Immune System during the Onset of Infection Elías Barquero-Calvo, Esteban Chaves-Olarte, David S. Weiss, Caterina Guzmán-Verri, Carlos Chacón-Díaz, Alexandra Rucavado, Ignacio Moriyón, and Edgardo Moreno PMCID: PMC1910614 Problem-Based Versus Conventional Curricula: Influence on Knowledge and Attitudes of Medical Students Towards Health Research Hassan Khan, Ather M. Taqui, Muhammad Rizwanulhaq Khawaja, and Zafar Fatmi PMCID: PMC1913552 A Model for the Interplay of Receptor Recycling and Receptor-Mediated Contact in T Cells Sergey N. Arkhipov and Ivan V. Maly PMCID: PMC1920549 Population Bottlenecks Promote Cooperation in Bacterial Biofilms Michael A. Brockhurst PMCID: PMC1919422 Polyglutamine Expansion Mutation Yields a Pathological Epitope Linked to Nucleation of Protein Aggregate: Determinant of Huntington's Disease Onset Keizo Sugaya, Shiro Matsubara, Yasuhiro Kagamihara, Akihiro Kawata, and Hideaki Hayashi PMCID: PMC1914377 Stable Isotope Ratios in Hair and Teeth Reflect Biologic Rhythms Otto Appenzeller, Clifford Qualls, Franca Barbic, Raffaello Furlan, and Alberto Porta PMCID: PMC1919425 Single Trial Classification of Motor Imagination Using 6 Dry EEG Electrodes Florin Popescu, Siamac Fazli, Yakob Badower, Benjamin Blankertz, and Klaus-R. Müller PMCID: PMC1914378 Simple PCR Assays Improve the Sensitivity of HIV-1 Subtype B Drug Resistance Testing and Allow Linking of Resistance Mutations Jeffrey A. Johnson, Jin-Fen Li, Xierong Wei, Jonathan Lipscomb, Diane Bennett, Ashley Brant, Mian-er Cong, Thomas Spira, Robert W. Shafer, and Walid Heneine PMCID: PMC1919426 Vision and Foraging in Cormorants: More like Herons than Hawks? Craig R. White, Norman Day, Patrick J. Butler, and Graham R. Martin PMCID: PMC1919429 Common HLA Alleles Associated with Health, but Not with Facial Attractiveness Vinet Coetzee, Louise Barrett, Jaco M. Greeff, S. Peter Henzi, David I. Perrett, and Ahmed A. Wadee PMCID: PMC1919430 Expression and Function of Cannabinoid Receptors CB1 and CB2 and Their Cognate Cannabinoid Ligands in Murine Embryonic Stem Cells Shuxian Jiang, Yigong Fu, John Williams, JodiAnne Wood, Lakshmipathi Pandarinathan, Shiri Avraham, Alexandros Makriyannis, Shalom Avraham, and Hava Karsenty Avraham PMCID: PMC1919431 Control of Flowering Time and Cold Response by a NAC-Domain Protein in Arabidopsis So Yeon Yoo, Yunhee Kim, Soo Young Kim, Jong Seob Lee, and Ji Hoon Ahn PMCID: PMC1920552 The Cis-regulatory Logic of the Mammalian Photoreceptor Transcriptional Network Timothy H.-C. Hsiau, Claudiu Diaconu, Connie A. Myers, Jongwoo Lee, Constance L. Cepko, and Joseph C. Corbo PMCID: PMC1916400 How Plastic Can Phenotypic Plasticity Be? The Branching Coral Stylophora pistillata as a Model System Lee Shaish, Avigdor Abelson, and Baruch Rinkevich PMCID: PMC1924915 Rapid Identification of Malaria Vaccine Candidates Based on α-Helical Coiled Coil Protein Motif Viviane Villard, George W. Agak, Géraldine Frank, Ali Jafarshad, Catherine Servis, Issa Nébié, Sodiomon B. Sirima, Ingrid Felger, Myriam Arevalo-Herrera, Socrates Herrera, Frederic Heitz, Volker Bäcker, Pierre Druilhe, Andrey V. Kajava, and Giampietro Corradin PMCID: PMC1920550 Neural Decision Boundaries for Maximal Information Transmission Tatyana Sharpee and William Bialek PMCID: PMC1920551 Early Energy Deficit in Huntington Disease: Identification of a Plasma Biomarker Traceable during Disease Progression Fanny Mochel, Perrine Charles, François Seguin, Julie Barritault, Christiane Coussieu, Laurence Perin, Yves Le Bouc, Christiane Gervais, Guislaine Carcelain, Anne Vassault, Josué Feingold, Daniel Rabier, and Alexandra Durr PMCID: PMC1919424 Phenotypic Diversity and Altered Environmental Plasticity in Arabidopsis thaliana with Reduced Hsp90 Levels Todd A. Sangster, Adam Bahrami, Amity Wilczek, Etsuko Watanabe, Kurt Schellenberg, Catherine McLellan, Alicia Kelley, Sek Won Kong, Christine Queitsch, and Susan Lindquist PMCID: PMC1920555 Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection Michaela Lucas, Axel Ulsenheimer, Katja Pfafferot, Malte H.J. Heeg, Silvana Gaudieri, Norbert Grüner, Andri Rauch, J. Tilman Gerlach, Maria-Christina Jung, Reinhart Zachoval, Gerd R. Pape, Winfried Schraut, Teresa Santantonio, Hans Nitschko, Martin Obermeier, Rodney Phillips, Thomas J. Scriba, Nasser Semmo, Cheryl Day, Jonathan N. Weber, Sarah Fidler, Robert Thimme, Anita Haberstroh, Thomas F. Baumert, Paul Klenerman, and Helmut M. Diepolder PMCID: PMC1920556 Complete Mitochondrial Genome Sequence of Three Tetrahymena Species Reveals Mutation Hot Spots and Accelerated Nonsynonymous Substitutions in Ymf Genes Mike M. Moradian, Denis Beglaryan, Jill M. Skozylas, and Varand Kerikorian PMCID: PMC1919467 Large-Scale In Silico Mapping of Complex Quantitative Traits in Inbred Mice Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, and Ming You PMCID: PMC1920557 Heterologous Amyloid Seeding: Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease Létitia Jean, Benjamin Thomas, Abdessamad Tahiri-Alaoui, Michael Shaw, and David J. Vaux PMCID: PMC1920558 Small Oscillatory Accelerations, Independent of Matrix Deformations, Increase Osteoblast Activity and Enhance Bone Morphology Russell Garman, Clinton Rubin, and Stefan Judex PMCID: PMC1919432 Can Echocardiographic Findings Predict Falls in Older Persons? Nathalie van der Velde, Bruno H. Ch. Stricker, Jos R. T. C. Roelandt, Folkert J. Ten Cate, and Tischa J. M. van der Cammen PMCID: PMC1920553 Shift Towards Pro-inflammatory Intestinal Bacteria Aggravates Acute Murine Colitis via Toll-like Receptors 2 and 4 Markus M. Heimesaat, André Fischer, Britta Siegmund, Andreas Kupz, Julia Niebergall, David Fuchs, Hannah-Katharina Jahn, Marina Freudenberg, Christoph Loddenkemper, Arvind Batra, Hans-Anton Lehr, Oliver Liesenfeld, Michael Blaut, Ulf B. Göbel, Ralf R. Schumann, and Stefan Bereswill PMCID: PMC1914380 Printing Multistrain Bacterial Patterns with a Piezoelectric Inkjet Printer Jack Merrin, Stanislas Leibler, and John S. Chuang PMCID: PMC1914381 HLA-A Confers an HLA-DRB1 Independent Influence on the Risk of Multiple Sclerosis Boel Brynedal, Kristina Duvefelt, Gudrun Jonasdottir, Izaura M. Roos, Eva Åkesson, Juni Palmgren, and Jan Hillert PMCID: PMC1919434 Novel Peptide Sequence (“IQ-tag”) with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging Kimberly A. Kelly, Jonathan Carson, Jason R. McCarthy, and Ralph Weissleder PMCID: PMC1919420 The Perils of Picky Eating: Dietary Breadth Is Related to Extinction Risk in Insectivorous Bats Justin G. Boyles and Jonathan J. Storm PMCID: PMC1914379 A Modern Mode of Activation for Nucleic Acid Enzymes Dominique Lévesque, Francis P. Brière, and Jean-Pierre Perreault PMCID: PMC1919428 Commensal Bacteria and Expression of Two Major Intestinal Chemokines, TECK/CCL25 and MEC/CCL28, and Their Receptors François Meurens, Mustapha Berri, Richard H. Siggers, Benjamin P. Willing, Henri Salmon, Andrew G. Van Kessel, and Volker Gerdts PMCID: PMC1919421 Screen for ISG15-crossreactive Deubiquitinases André Catic, Edda Fiebiger, Gregory A. Korbel, Daniël Blom, Paul J. Galardy, and Hidde L. Ploegh PMCID: PMC1919423 |
