Intervention Strategies for Injection and Non-Injection Drug Users To Reduce the Risk of HIV and Other STIs
Introduction and Goals
Numerous studies have shown that injecting drug users (IDUs) who engage in multiperson sharing of needles and syringes have an increased risk for HIV transmission. Drug-related risk behaviors, including exchange of sex for drugs or money, have also been independently associated with HIV infection.
Injection-related risk behaviors account for the majority of new HIV infections in many parts of the world, including Eastern Europe, Russia, and Southeast Asia. Rapid HIV transmission among populations and social groups associated with injection drug use in low prevalence settings is leading to new epidemics in many countries.
Research has shown that substance abuse treatment programs, which aim to reduce the frequency of drug use, have made a positive impact on reducing drug-related risk behaviors and subsequent HIV exposure. Risk reduction among active drug users has also been accomplished in various settings via community outreach programs and access to sterile injection equipment.
Nevertheless, preventing HIV transmission among non-injecting and injecting drug users remains an urgent and expanding public health problem in many regions of the world. The NIAID HIV prevention portfolio includes a number of scientific priorities which address risk reduction for HIV and other STIs among injecting and non-injecting drug users. These priorities include
- Reducing risk of drug-associated and sexual transmission of HIV among injecting and non-injecting substance users
- Developing and refining primary and secondary prevention interventions for HIV-infected drug users
- Developing interventions designed to overcome structural and community-level barriers to accepting and implementing effective HIV prevention strategies
Research Activities
NIAID is supporting a number of research studies to develop strategies to reduce the risk of HIV and other STIs for injecting and non-injecting drug users.
- HIV Prevention Trials Network (HPTN)
Co-sponsored by NIAID, the National Institute of Child Health and Human Development, the National Institute of Mental Health, and the National Institute on Drug Abuse, the HPTN is a worldwide collaborative clinical trials network that develops and tests the safety and efficacy of primarily non-vaccine interventions designed to prevent the transmission of HIV.
For more information about research at the HPTN on intervention strategies to reduce the risk of HIV and other STIs for injecting and non-injecting drug users, click here.
- CRISP database
This online database can be used to search for ongoing research supported by NIAID. (Keywords: Drug abuse prevention, IDU, HIV, risk reduction.)
- AIDSinfo
This government Web site has information on HIV/AIDS-related health topics, treatment and prevention guidelines, information on drugs and vaccines, and a database of all federally funded HIV/AIDS clinical trials.