The Mass Spectrometry Group conducts several research studies within the Laboratory of Structural Biology. For more information, please click the following links to individual project pages.
Tertiary Structural Characterization of Proteins & Protein Complexes (http://www.niehs.nih.gov/research/atniehs/labs/lsb/mass/studies/tertiary.cfm) discusses the group’s primary goal—to develop and apply mass spectrometry-based techniques to determine molecular recognition sites in protein complexes.
Characterization of Protein Posttranslational Modifications (http://www.niehs.nih.gov/research/atniehs/labs/lsb/mass/studies/characterization.cfm)
highlights the importance of understanding these processes and their involvement in the regulation and activity of proteins.
Oxidative Stress (http://www.niehs.nih.gov/research/atniehs/labs/lsb/mass/studies/oxidative.cfm) damages tissues and leads to illnesses such as cancer and coronary artery disease. The group uses mass spectroscopy to study this damage.
Quantitative Mass Spectrometry (http://www.niehs.nih.gov/research/atniehs/labs/lsb/mass/studies/spectrometry.cfm) allows the group to provide quantitative analysis of specific metabolic products.
Proteomics (http://www.niehs.nih.gov/research/atniehs/labs/lsb/mass/studies/proteomics.cfm) is the examination of an organism’s complete complement of proteins and the group uses this branch of study as the focus of collaborative research projects.
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