Agenda
Working Group on Current and Future
Directions in Stem Cell Transplantation for Hemoglobinopathies
August 10, 2000 8:15 a.m. - 4:00 p.m.
6701 Rockledge Drive, Room 9100-9104 Bethesda, Maryland 20892
8:15 - 8:30 a.m. Opening comments Director,
Division of Blood Diseases and Resources, NHLBI Dr. Barbara Alving Dr.
Helena Mishoe, NHLBI
(Chair) Dr. John DiPersio Washington
University School of Medicine
8:30 - 9:00 Dr. Mark Walters,
Childrens Hospital of Oakland Bone Marrow Transplantation for Sickle
Cell Disease: Results of a Multi-Center Investigation
9:00 - 9:30 Dr. David Rizzieri, Duke
University Medical Center Chimerism Mediated Immunotherapy for
Hemoglobinopathies
9:30 - 10:00 Dr. Suzanne Ildstad,
University of Louisville Mixed Chimerism to Treat Sickle Cell Disease in
MHC-Disparate Recipients
10:00 - 10:30 Break
10:30 - 11:00 Dr. John Barrett,
National Heart, Lung, and Blood Institute Non-myeloablative Transplants -
Efficacy and Side Effects Dr. John Tisdale, National Institute of Diabetes
and Digestive and Kidney Diseases, NIH
11:00 -11:30 Dr. John Wagner, University
of Minnesota Transplantation of Children and Adults with
Hemoglobinopathies
11:30 - Noon Dr. Nancy Geller, National
Heart, lung, and Blood Institute Potential Novel Trial Designs for Stem
Cell Transplantation
Noon - 12:30 P.M. Dr. David Kodish,
Rainbow Babies & Childrens Hospital Ethical Issues in Stem Cell
Transplantation for Hemoglobinopathies
12:30 - 2:00 LUNCH (working lunch
in small groups)
Toward Best Practices/Discussion Topics (Full
Working Group)
2:00 - 3:30
Patient Selection Criteria
Dr. Kwaku Ohene-Frempong, Childrens Hospital of
Philadelphia Dr. Lennette Benjamin, Albert Einstein
College of Medicine Dr. Orah Platt , Childrens
Hospital Medical Center
Timing of Transplants
Dr. Blanche Alter, Johns Hopkins School of Public Health
Service Dr. Jeanne Smith, Columbia University
Dr. Griffin Rodgers, National Institute of Diabetes and
Digestive and Kidney Diseases
Preparative Regimens
Dr. Barrett, National Heart, Lung, and Blood Institute
Dr. Rizzieri, Duke University Medical Center
Transplant Associated Risks
Dr. Suzanne Ildstad, University of Louisville
Dr. Mark Walters, Childrens Hospital of Oakland
Alternative Stem Cell Sources
Dr. John Wagner, University of Minnesota
Dr. John DiPersio, Washington University School of Medicine
Dr. John Tisdale, National Institute of Diabetes and
Digestive and Kidney Diseases
Patient/Parent Perspectives
Dr. Alan Cohen, Childrens Hospital of Philadelphia
Dr. David Kodish, Rainbow Babies & Childrens
Hospital (Parent and/or Patient)
3:30 - 4:00 Open Discussion/Summation
Dr. DiPersio, Washington University School of Medicine
4:00 Adjournment
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