Mission Statement:
Focuses on identifying the molecular components of intracellular signaling cascades.
Staff:
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Selected Publications:
Chen H, Puhl HL, Nui SL, Mitchell DC, Ikeda, SR: Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density. J Neurosci [in press] 2005.
Chen H and Ikeda SR: Modulation of ion channels and synaptic transmission by a human sensory neuron-specific G-protein coupled receptor, SNSR4/mrgX1, heterologously expressed in cultured rat neurons. J Neurosci 2004;24:504453. 
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Guo J and Ikeda SR: Endocannabinoids modulate N-type calcium channels and G-protein coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons. Mol Pharmacol 2004;65:66574. [PDF]
Kammermeier PJ and Ikeda SR: Expression of RGS2 alters the coupling of metabotropic glutamate receptor 1a to M-type K+ and N-type Ca2+ channels. Neuron 1999;22:81929.
keda SR: Voltage-dependent modulation of N-type calcium channels by G protein beta gamma subunits. Nature 1996;380:2558.
Korn SJ and Ikeda SR: Permeation selectivity by competition in a delayed rectifier potassium channel. Science 1995;269:4102.
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Updated: October 2005