| Agent Name |
Cyclohexanol |
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| CAS Number |
108-93-0 |
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| Formula |
C6-H12-O |
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| Major Category |
Solvents |
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| Synonyms |
1-Cyclohexanol; Adronal; Adronol; Anol; Cicloesanolo [Italian]; Cyclohexanol; Cyclohexanone cyclohexanol mixture; Cyclohexyl alcohol; Cykloheksanol [Polish]; Hexahydrophenol; Hexalin; Hydralin; Hydrophenol; Hydroxycyclohexane; Naxol; Phenol, hexahydro-; [ChemIDplus] UN1993 |
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| Category |
Alcohols and Polyols |
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| Description |
Sticky solid or colorless to light-yellow liquid (above 77 degrees F) with a camphor-like odor; [NIOSH] |
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| Sources/Uses |
Used in the production of nylon, paints, plastics, detergents, textiles, and pesticides; [ACGIH] |
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| Comments |
Liquid or solid form causes first degree burns on short exposure; [CHRIS] Skin absorption and narcosis seen in acute animal studies; [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] |
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| Exposure Assessment |
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| BEI |
Screen for 1,2-Cyclohexandiol (with hydrolysis) in urine at end of shift at end of workweek;Screen for Cyclohexanol (with hydrolysis) in urine at end of shift; |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
50 ppm |
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| PEL (OSHA) |
50 ppm |
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| MAK |
50 ppm |
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| IDLH (NIOSH) |
400 ppm |
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| Excerpts from Documentation for IDLHs |
Human data: The estimated acceptable concentration for 8 hours was reported in volunteers to be less than 100 ppm [Nelson et al. 1943]. |
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| Vapor Pressure |
0.8 mm Hg |
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| Odor Threshold Low |
0.05 ppm |
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| Odor Threshold High |
0.15 ppm |
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| Lethal Concentration |
LC (rats) > 6,500 mg/m3/1h (inhalation) |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.16 ppm); Flash point = 63 deg C; |
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| Half Life |
No reports found; [TDR, p. 430] |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Dermatotoxin |
Skin Burns |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CYCLOHEXANOL
|
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