| Agent Name |
n-Propyl acetate |
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| CAS Number |
109-60-4 |
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| Formula |
C5-H10-O2 |
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| Major Category |
Solvents |
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| Synonyms |
1-Acetoxypropane; 1-Propyl acetate; Acetate de propyle normal [French]; Acetic acid n-propyl ester; Acetic acid, propyl ester; Octan propylu [Polish]; Propyl acetate; Propyl ethanoate; Propylester kyseliny octove [Czech]; n-Propyl acetate; n-Propyl acetate (natural); n-Propyl ethanoate; [ChemIDplus] UN1276 |
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| Category |
Esters |
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| Description |
Colorless liquid with a mild, fruity odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent, flavoring agent, and chemical intermediate; [ACGIH] |
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| Comments |
Esters may induce narcosis in animals, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
200 ppm |
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| STEL (ACGIH) |
250 ppm |
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| PEL (OSHA) |
200 ppm |
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| MAK |
100 ppm |
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| IDLH (NIOSH) |
1700 ppm |
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| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by ACGIH [1971] that a 4�hour exposure to 8,000 ppm was fatal to 4 of 6 rats [Smyth et al. 1954]. . . . Human data: None relevant for use in determining the revised IDLH. |
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| Vapor Pressure |
35.9 mm Hg |
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| Odor Threshold Low |
0.04 ppm |
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| Odor Threshold High |
0.7 ppm |
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| Lethal Concentration |
LCLo (rats) = 8,000 ppm/4H |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.18 ppm); Flash point = 14 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-PROPYL ACETATE
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