Agent Name |
o-Methylcyclohexanone |
CAS Number |
583-60-8 |
Formula |
C7-H12-O |
Major Category |
Solvents |
Synonyms |
2-Methyl-1-cyclohexanone; 2-Methyl-cyclohexanon [German, Dutch]; 2-Methylcyclohexanone; 2-Metilcicloesanone [Italian]; Methylanon; Sexton B; alpha-Methylcyclohexanone; o-Methylcyclohexanone; [ChemIDplus] UN2297 |
Category |
Ketones |
Description |
Colorless liquid with a weak, peppermint-like odor; [NIOSH] |
Sources/Uses |
Used as a rust remover and a solvent to make lacquers, varnishes, and plastics; Used in the leather industry; [ACGIH] |
Comments |
Narcosis occurs in animal inhalation studies; [ACGIH] A skin, eye, and respiratory tract irritant; [CAMEO] |
Exposure Assessment |
Skin Designation (ACGIH) |
Yes |
TLV (ACGIH) |
50 ppm |
STEL (ACGIH) |
75 ppm |
PEL (OSHA) |
100 ppm |
IDLH (NIOSH) |
600 ppm |
Excerpts from Documentation for IDLHs |
Other animal data: Mice, guinea pigs, and rats exposed at 3,500 ppm for 30 minutes suffered irritation of the mucous membranes and exhibited signs of central nervous system depression [Clayton and Clayton 1981]. Rabbits and cats exhibited sleepiness, respiratory irregularities, and poor coordination after a 1�hour exposure to 2,500 ppm [Clayton and Clayton 1981]. |
Vapor Pressure |
2.25 mm Hg |
Odor Threshold Low |
0.5 ppm |
Lethal Concentration |
LCLo (rats) = 2,800 ppm/4H |
Explanatory Notes |
Flash point = 118 deg F; Odor threshold from CHEMINFO; |
Flammability (NFPA) |
2: high ambient temperature required |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-METHYLCYCLOHEXANONE
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