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Agent Name Isobutyl acetate
CAS Number 110-19-0
Formula C6-H12-O2
Major Category Solvents
Synonyms 2-Methyl-1-propyl acetate; 2-Methylpropyl acetate; 2-Methylpropyl ethanoate; Acetate d'isobutyle [French]; Acetic acid, isobutyl ester; Isobutyl acetate; Isobutyl acetate (natural); Isobutyl ethanoate; Isobutylester kyseliny octove [Czech]; beta-Methylpropyl ethanoate; [ChemIDplus] UN1213
Category Esters
Description Colorless liquid with a fruity, floral odor; [NIOSH]
Sources/Uses Used as a solvent and flavoring agent; [ACGIH] Solvent uses include nitrocellulose, thinners, sealants, lacquers, and perfumes; [Hawley]
Comments A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 150 ppm
PEL (OSHA) 150 ppm
MAK 100 ppm
IDLH (NIOSH) 1300 ppm
Excerpts from Documentation for IDLHs Basis for original (SCP) IDLH: The chosen IDLH is based on the following statements: a 4�hour exposure to 8,000 ppm killed 4 of 6 rats [UCC 1971; Smyth et al. 1962 as cited by ACGIH 1971] and no deaths resulted from a 4�hour exposure of 6 rats to 4,000 ppm [UCC 1971; Smyth 1964 as cited by ACGIH 1971]. . . . Human data: None relevant for use in determining the revised IDLH;
Vapor Pressure 17.8 mm Hg
Odor Threshold Low 0.36 ppm
Odor Threshold High 3.6 ppm
Lethal Concentration LCLo (rats) = 8,000 ppm/4H
Explanatory Notes IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 1.1 ppm); Flash point = 18 deg C;
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: ISOBUTYL ACETATE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009