Agent Name |
Methyl propyl ketone |
Alternative Name |
2-Pentanone |
CAS Number |
107-87-9 |
Formula |
C5-H10-O |
Major Category |
Solvents |
Synonyms |
2-Pentanone (natural); Ethyl acetone; Ethylacetone; Methyl n-propyl ketone; Methyl propyl ketone; Methyl-propyl-cetone [French]; Methylpropyl ketone; Metylopropyloketon [Polish]; Propyl methyl ketone; MPK; [ChemIDplus] UN1249 |
Category |
Ketones |
Description |
Colorless to water-white liquid with a characteristic acetone-like odor; [NIOSH] |
Sources/Uses |
Used as a solvent, a flavoring agent, and in organic synthesis; [ACGIH] Used as a solvent for lacquers and surface coatings; [HSDB] |
Comments |
Causes CNS depression and fatty degeneration of the liver after inhalation of high doses by experimental animals; A respiratory tract irritant; [ACGIH] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
STEL (ACGIH) |
150 ppm |
PEL (OSHA) |
200 ppm |
IDLH (NIOSH) |
1500 ppm |
Excerpts from Documentation for IDLHs |
Exposure to a concentration of 1,500 ppm was associated with complaints of ocular and upper respiratory irritation [Yant et al. 1936]. |
Vapor Pressure |
35.4 mm Hg |
Odor Threshold Low |
3.1 ppm |
Odor Threshold High |
13.6 ppm |
RD50 |
12832 ppm |
Lethal Concentration |
LCLo (rats) = 2,000 ppm/4H |
Explanatory Notes |
Detection odor threshold from AIHA (mean = 7.7 ppm); Flash point equals 7 deg C; [ACGIH] |
Flammability (NFPA) |
3: may ignite at ambient temperature |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: METHYL PROPYL KETONE
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