Agent Name |
1,1,2-Trichloroethane |
CAS Number |
79-00-5 |
Formula |
C2-H3-Cl3 |
Major Category |
Solvents |
Synonyms |
Ethane trichloride; beta-Trichloroethane; Vinyl trichloride; [NIOSH] UN8027 |
Category |
Chlorinated Aliphatic |
Description |
Colorless liquid with a sweet, chloroform-like odor; [NIOSH] |
Sources/Uses |
Used primarily for synthesis of vinylidene chloride; also used as a solvent in pharmaceutical manufacturing; [ACGIH] Used in lacquers, adhesives, and resins; [HSDB] |
Comments |
Acute animal studies: narcosis, anesthesia, and injury to the liver and kidneys; [ACGIH] |
Exposure Assessment |
Skin Designation (ACGIH) |
Yes |
TLV (ACGIH) |
10 ppm |
PEL (OSHA) |
10 ppm |
MAK |
10 ppm |
IDLH (NIOSH) |
100 ppm |
Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1972] report that 500 ppm killed 1 of 6 rats in 4 hours, and 4 of 6 rats in 8 hours. . . . Human data: None relevant for use in determining the revised IDLH. |
Vapor Pressure |
19 mm Hg |
Odor Threshold Low |
0.5 ppm |
Odor Threshold High |
167 ppm |
Lethal Concentration |
LCLo (rats) = 500 ppm/4H |
Explanatory Notes |
Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; |
Reference Link |
ATSDR ToxFAQs - 1,1,2-Trichloroethane |
Flammability (NFPA) |
1: must be preheated |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Hepatotoxin |
Hepatotoxin, Secondary |
IARC Carcinogen |
Not Classifiable |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,1,2-TRICHLOROETHANE
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