Session I: Adipose Fate Determination (Precursor/Progenitor Cells)
C. Ronald Kahn (Moderator) |
10:30–11:00 a.m. |
Fat Cell Progenitors: Origin and Plasticity
Christian Dani, Ph.D., University of Nice |
11:00–11:30 a.m. |
The Tortuous Path of the Adipogenic Lineage
Jonathan Graff, M.D., Ph.D., University of Texas Southwestern Medical Center |
11:30–12:00 p.m. |
Distinct Origins of Brown and White Adipocytes
Barbara Cannon, Ph.D., The Wenner-Gren Institute/Stockholm University |
12:00–12:30 p.m. |
PRDM16 Controls the Determination of Brown Fat Cells From Myogenic Precursors
Patrick Seale, Ph.D., Dana-Farber Cancer Institute/Harvard Medical School |
12:30–2:30 p.m. |
Poster Session and Lunch Buffet in Atrium |
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Session II: Development of the Niche (Role of Secreted Signals and the ECM)
Jon Graff (Moderator) |
2:30–3:00 p.m. |
Role of Wnt Signaling in Development of Adipose Tissues and Bone
Ormond MacDougald, Ph.D., University of Michigan |
3:00–3:30 p.m. |
Adipose Tissue and Adipose Tissue Vasculature
Development: Depot Dependent Expression of Genes and Proteins
Gary Hausman, Ph.D., University of Georgia |
3:30–4:00 p.m. |
Collagenolytic Remodeling of Fat Tissue Architecture During Obesity Progression
Tae-Hwa Chun, M.D., Ph.D., University of Michigan |
4:00–4:30 p.m. |
Break |
4:30–5:00 p.m. |
Novel Role of Bone Morphogenetic Protein-7 in Brown Adipogenesis and Energy Expenditure
Yu-Hua Tseng, Ph.D., Joslin Diabetes Center, Harvard University |
5:00–5:15 p.m. |
Hot Topic—Mapping the Adipogenic Lineage of the Human Mesenchymal Stem Cell
Danielle MacKay, Ph.D., Case Western Reserve University |
5:15–5:30 p.m. |
Hot Topic—Myostatin, Activin Receptor IIb and Follistatin-like Gene Expression is Altered in Adipose Tissue of Obese Mice
David Allen, Ph.D., University of Colorado, Boulder |
5:30 p.m. |
Adjourn |
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Day 2 Thursday, May 22, 2008 |
7:30–8:00 a.m. |
Registration and Continental Breakfast
(Lister Hill Auditorium, NIH Campus) |
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Session III: Cellular Diversity and Turnover in Fat Depots
Jim Granneman (Moderator) |
8:00–8:30 a.m. |
Regional Differences in Preadipocytes: Are Different Fat Depots Distinct Mini-Organs?
James Kirkland, M.D., Ph.D., Boston University |
8:30–9:00 a.m. |
A Role of p107 in Mesodermal Cell Fate Decisions
Anthony Scime, Ph.D., University of Ottawa |
9:00–9:15 a.m. |
Hot Topic—Functions of PPARγ in Early Adipogenesis in vivo and in vitro
Suyeon Kim, Ph.D., The Jackson Laboratory |
9:15–9:30 a.m. |
Hot Topic—Atf4 Mutant Mice are Lean
Jin Seo, Ph.D., University of Texas Southwestern Medical Center |
9:30–10:00 a.m. |
Break |
10:00–10:30 a.m. |
Critical Factors Restricting Fat Expansion
Phillip Scherer, Ph.D., University of Texas Southwestern Medical Center |
10:30–11:00 a.m. |
Dynamics of Adipose Tissue Components in Vivo in Experimental Animals and Humans: Modulation by Genes, Hormones and Drugs
Marc Hellerstien, M.D., Ph.D., University of California at Berkeley |
11:00–11:15 a.m. |
Hot Topic—Dysregulation of Adipocyte Biology and Metabolic Profile by Ablation of α3(V) Collagen
Daniel Greenspan, Ph.D., University of Wisconsin |
11:15–11:30 a.m. |
Hot Topic—Cidea and FSP27: Novel Proteins Associated with Fat Metabolism and Insulin Sensitivity in Humans
Vishwajeet Puri, Ph.D., University Massachusetts Medical School |
11:30–11:45 a.m. |
Hot Topic—Factors Contributing to Metabolically Normal Adiposity
Nikhil Dhurandhar, Ph.D., Pennington, Louisiana State University System |
11:45–1:15 p.m. |
Poster Session and Lunch Buffet |
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Session IV: Remodeling and Plasticity of Fat Depots Phillip Gorden (Moderator) |
1:15–1:45 p.m. |
Cellular and Metabolic Plasticity of White Adipose Tissue: Effects of β-Adrenergic Stimulation
James Granneman, Ph.D., Wayne State University |
1:45–2:15 p.m. |
Depot Selective Role for Macrophages in Obesity-Associated Adipose Tissue Remodeling
Martin Obin, Ph.D., Tufts University |
2:15–2:45 p.m. |
Exploring Inflammatory Links Between Obesity and Diabetes
Alan Saltiel, Ph.D., University of Michigan |
2:45–3:15 p.m. |
Bone Marrow Mesenchymal Progenitor Cells Give Rise to a Unique Adipocyte Population in Adipose Tissue
Dwight Klemm, Ph.D., University of Colorado Health Sciences Center |
3:15–3:30 p.m. |
Hot Topic—Identification of G0S2 as a Novel Bcl-2 Binding Protein Regulator in Adipocytes
Jun Liu, Ph.D., University of Kentucky, School of Medicine |
3:30–3:45 p.m. |
Hot Topic—Rapid Improvement of Glucose Tolerance Independent of Loss of Weight by a Peptide Inducing Apoptosis in Endothelium of White Adipose Tissue
Dong-Hoon Kim, M.D., University of Cincinnati |
3:45–4:00 p.m. |
Closing Remarks |
4:00 p.m. |
Adjourn |
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