Cancer Control Research
5R01CA075614-02
Baranowski, Tom
GIMME 5--INTERACTIVE MULTIMEDIA EDUCATION (G5-IMME)
AbstractSeveral national dietary guidelines have promoted the consumption of 5
to 9 servings of fruit and vegetables (F&V) every day, but children
are only eating about 2.3 servings a day. Existing school based
nutrition education curricula have encountered difficulties in the extent
to which the educational activities likely to result in dietary change
have been implemented. Interactive Multimedia provide exciting
opportunities for directly reaching students and providing programs
that are engaging, based on social cognitive theory, and likely to
result in change.
This project adapts the successful Gimme 5 classroom curriculum to
interactive multimedia format. Based on previous research, Gimme 5
increases F&V availability and accessibility at home and at fast food
places by modeling students' asking behaviors and encouraging parents
to purchase more F&V through newsletters sent home and joint parent-
child home assignments; increases students' preferences for F&V by
taste-testing of proven preferred recipes, fun activities, and showing
students enjoying consumption of F&V; increases students' skills in
F&V preparations by sending recipes to parents and encouraging child
preparation of the recipes under parent supervision; promotes goal-
setting for F&V changes at alternative meals and snacks; and promotes
problem solving skills for initial Change goals not attained. The
strengths of interactive multimedia are incorporated by use of modeling
of desired asking and food preparation behaviors by attractive peers,
use fantasy in animations, encouraging skill building by presenting
students with real life decisions and experiencing the consequences of
their alternative decisions, tailoring of motivational messages to student
outcome expectations, and tailoring of goals to child's dietary practices,
preferences and desired schema for eating more F&V. Participation in
this study will take approximately 8 weeks per student, or 1 school
year to complete. Hypotheses will be tested in regard to dietary
outcomes and psychosocial and family mediators of program outcomes.
This research will be the firs test of interactive multimedia for dietary
behavior change among elementary school students.
The project combines the many years of expertise of the school
nutrition education team at the University of Texas M.D. Anderson
Cancer Center and the Multimedia Laboratory at the University of
Texas Medical Branch-Galveston with the Houston Independent School
District.
Grant=R01EY05133
The long-term objectives of this project are to define the key events
in the inductive and effector pathways leading to ocular mucosal-
associated immune responses. The hypotheses to be tested are: that
nasal-associated lymphoid tissue is the primary mucosal inductive site
for eliciting tear IgA antibodies following topical antigen administration
to the conjunctiva; that a specific lymphocyte receptor mediates the
localization of lymphoid populations within lacrimal gland tissues; and
that the lymphocyte receptor interacts with an adhesion (or ligand)
molecule produced by acinar epithelial cells located within the lacrimal
gland. The specific aims are: 1. To define the mucosal inductive
pathway(s) that leads to the expression of IgA antibodies in tears.
this aim will compare the uptake and distribution of antigen following
ocular topical and nasal-associated lymphoid tissue delivery and
determine the effects of mucosal signal delivery on trafficking of
antibody forming cells to lacrimal glands. 2. To isolate and
characterize the lymphocyte receptor that mediates the localization of
lymphoid populations within lacrimal gland tissues. This aim will
determine the structure of the isolated lymphocyte receptor at the
molecular level and assess receptor distribution and function. 3. To
isolate and characterize the acinar epithelial cell adhesion (or ligand)
molecule that mediates lymphocyte retention with lacrimal gland tissues.
this aim will determine the structure of the isolated lacrimal gland
epithelial cell adhesion (or ligand) molecular and define the mechanism
by which it functions to mediate lymphocyte retention with the lacrimal
gland interstitium. Investigations in the rat model will utilize
biochemical, immunological and molecular approaches together with cell
and tissue culture systems, adherence and motility assays and flow
cytometry. these investigations will provide new information applicable
to the design of clinically relevant mucosal immunization strategies to
protect external ocular surfaces.
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