Chun, KS, Akunda, JK, Langenbach, R. Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4. Cancer Res. 2007;67(5):2015-21.
Toscano, CD, Prabhu, VV, Langenbach, R, Becker, KG, Bosetti, F. Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain. Genome Biol. 2007;8(1):R14.
Akunda JK, Chun KS, Sessoms AR, Lao HC, Fischer SM, Langenbach R. Cyclooxygenase-2 deficiency increases epidermal apoptosis and impairs recovery following acute UVB exposure. Mol. Carcinog. 2007, 46:354-262.
Fischer SM, Pavone A, Mikulec C, Langenbach R, Rundhaug JE. Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis. Mol. Carcinog. 2007; 46:363-371.
Akunda, A.K., Lao, H-C, Lee, C.A., Sessoms, A.R., Slade, R. and Langenbach, R,. Deficiency or Pharmacological Inhibition of Cyclooxygenase-1 or -2 Induces Mouse Keratinocyte Differentiation in-vivo and in-vitro. FASEB J. 18: 185-187 (2004). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14630706&query_hl=31)
Gray, T., Nettesheim, P., Loftin, C., Tiano. H., Koo, J.-S., and Langenbach, R., IL-1 _ Induced MUC5AC Mucin Production in Normal Human Airway Epithelium is Mediated by EP Receptor:c-AMP/PKA Signaling. Mol. Pharmacol. 66: 337-346 (2004). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15266025&query_hl=27)
Okeda, H., Oshima, H., Chulada, P.C., Langenbach, R., Oshima, M., and Taketo, M.M. Cooperation of cyclooxygenase 1 and Cyclooxygenase 2 in Intestinal polyposis. Cancer Res. 63:4872-4877 (2003). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieveamp;&db=pubmed&dopt=Abstract&list_uids=12941808&query_hl=25)
Loftin, C. D., Trivedi, D., Tiano, H.F. and Langenbach, R. Cyclooxygenase-1-Selective Inhibition Prolongs Gestation in Mice and Lacks Adverse Effects on the Ductus Arteriosus. J. Clin. Invest. 110:549-557 (2002). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12189249&query_hl=23)
Tiano, H., Loftin, C., Akunda, J., Lee, C., Spalding, J., Sessoms, A., Dunson, D., Rogan, E., Morham, S., Smart, R. and Langenbach, R. Deficiency of Cyclooxygenase-1 or Cyclooxygenase-2 Alters Epidermal Differentiation and Reduces Mouse Skin Tumorigenesis. Cancer Res. 62:3395-3401 (2002). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12067981&query_hl=15)
Bonner, J.C., Rice, A.B., Moomaw, C.R., Nyska, A., Bradbury, A., Chulada, P.C, Morgan, D..L., Zeldin, D.C. and Langenbach, R. Susceptibility of Cyclooxygenase (COX)-2 Deficient Mice to Pulmonary Fibrogenesis. Amer. J. Pathol. 161:459-470 (2002). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12163371&query_hl=13)
Loftin, C. D., Tiano, H. F., Trivedi, D.B., Clark, J.A., Lee, C. A., Epstein, J.A., Breyer, M.D., Morham, S. G., Koller, B.H., Smithies, O. and Langenbach, R. Failure of Ductus Arteriosus Closure and Remodeling in Neonatal Mice Deficient in Both Cyclooxygenase-1 and Cyclooxygenase-2. Proc. Natl. Acad. Sci. USA. 98:1059-1064 (2001). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11158594&query_hl=10)
Chulada, P. C., Thompson, M. B., Mahler, J. F., Doyle, C. M., Gaul, B. W., Lee, C., Tiano, H. F., Morham, S. G., Smithies, O. and Langenbach, R. Genetic Disruption of Ptgs-1 , as well as of Ptgs-2 , Reduces Intestinal Tumorigenesis in Min Mice. Cancer Res. 60:4705-4708 (2000). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10987272&query_hl=8)
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