Our Science – Sommers Website

Connie Sommers, Ph.D.

Laboratory of Cellular and Molecular Biology Staff Scientist LCMB/CCR/NCI/NIH Bldg. 37, Rm. 2066 37 Convent Drive Bethesda, MD 20892-4256 Phone:   301-496-8910 Fax:   301-496-8479 E-Mail:   connies@helix.nih.gov

Research

Our research focuses on deciphering the role of LAT in T cell development and T cell function using transgenic mouse models. In particular, a knock-in mutant of LAT (LATY136F) has revealed an important role for LAT in immune homeostasis since these knock-in mice have a severe lymphoproliferative disease. Our research also investigates the roles of other T cell signal transduction intermediates in the development and function of LATY136F and normal T cells.

This page was last updated on 7/15/2008.