NIDDK New Research Directions in Urinary Incontinence Symposium

DRAFT AGENDA
Wednesday, January 7, 2009: 1:00 – 5:00 p.m.
12:30 – 1:00 p.m.	Registration
1:00 – 1:20 p.m.	Introduction and Welcome – Debuene Chang, M.D. Introduction: New Research Directions – Deborah Lightner, M.D., Chair
1:20 – 2:15 p.m.	Current NIH Supported Research: Moderator – Debuene Chang, M.D.
	1:20 – 1:35 p.m.	NIDDK’s Review of NIDDK’s UITN – Elizabeth Gormley, M.D.
	1:35 – 1:50 p.m.	Review of NICHD’s PFDN – Holly Richter, M.D., Ph.D.
	1:50 – 2:05 p.m.	“Future Epidemiologic and Health Services Research on Urinary Incontinence”: NIDDK’s BACH Study – Dr. John McKinlay, Ph.D.
	2:05 – 2:15 p.m.	Questions & Answers
2:15 – 2:25 p.m.	NIDDK Institutes Directors Welcome: – Griffin Rodgers, M.D.
2:25 – 3:50 p.m.	New Research on Whom?: Moderator – Jennifer Anger, M.D.
	2:25 – 2:40 p.m.	Epidemiology/Natural History – Steinar Hunskår, Ph.D.
	2:40 – 2:55 p.m.	Continence Promotion: What the Whole Population Needs to Know: Vulnerable Populations, Older Adults, Women Having Babies, Men Post Prostatectomy (PPI) – Diane Newman, M.S.N.
	2:55 – 3:10 p.m.	Prevention – Ananias Diokno, M.D.
	3:10 – 3:25 p.m.	The Genetics of the At Risk Population – Bertha Chen, M.D.
	3:25 – 3:40 p.m.	Pregnancy/Partuition – Carolyn Sampselle, Ph.D., R.N.C.
	3:40 – 3:50 p.m.	Questions & Answers
3:50 – 4:35 p.m.	Basic Research: Moderator – Margot Damaser, Ph.D.
	3:50 – 4:05 p.m.	Animal Model of OAB and CRH – Rita Valentino, Ph.D.
	4:05 – 4:20 p.m.	Mechanisms of Childbirth Injury Leading to SUI – Margot Damaser, Ph.D.
	4:20 – 4:35 p.m.	OAB/Urge Incontinence – Toby Chai, M.D.
5:00 – 8:00 p.m.	Poster Session I: Basic Science – Light Snack and Dinner (provided) 2 Announced Awards and 3 Honorable Mentions

Thursday, January 8, 2009: 8:00 a.m. – 5:00 p.m.
8:00 – 8:15 a.m.	Announcements: (2) Awards from last night
8:15 –9:00 a.m.	Aging: Moderator – Patricia Goode, M.D.
	8:15 – 8:30 a.m.	Nocturia in Men and Women – Mary Pat Fitzgerald, M.D.
	8:30 – 8:45 a.m.	Incontinence in LUTS in Women – Holly Richter, M.D., Ph.D.
	8:45 – 9:00 a.m.	Incontinence in LUTS in Aging Men – Tomas Griebling, M.D.
9:00 – 9:30 a.m.	Economics: Moderator – Tomas Griebling, M.D.
	9:00 – 9:15 a.m.	The Costs for Women: for Management and for Treatment – Leslee Subak, M.D.
	9:15 – 9:30 a.m.	Natural History: Complication of Untreated Incontinence – Jeanette Brown, M.D.
9:30 – 9:40 a.m.	BREAK
9:40 – 12:00 p.m.	How Close are We to the Outcomes Patients Want?: Moderator – Kimberly Kenton, M.D.
	9:40 – 10:00 a.m.	Role of UDS – Charlie Nager, M.D.
	10:00 – 10:20 a.m.	Q-O-L – Lior Lowenstein, M.D.
	10:20 – 10:40 a.m.	PPI patient satisfaction – Ajay Singla, M.D. (ICS course)
	10:40 – 11:00 a.m.	Population Measures – Jennifer Anger, M.D.
	11:00 – 11:20 a.m.	What Outcomes Matter? Objective versus Subjective; General Health versus Disease Specific; Correlation between Outcomes – Linda Brubaker, M.D.
	11:20 – 12:00 p.m.	Panel: Minimum Important Outcomes for Reporting including Complications – What Do We Need Most?
12:00 – 12:15 p.m.	Degenerative Disease: Parkinsonism, MS – Gary Lemack, M.D.
12:15 – 1:00 p.m.	LUNCH
1:00 – 2:05 p.m.	Complications of Treatment: Moderator – Kathleen Kobashi, M.D.
	1:00 – 1:15 p.m.	Synthetics – Jan Deprest, M.D., Ph.D.
	1:15 – 1:30 p.m.	Autologous – Fred Govier, M.D.
	1:30 – 1:45 p.m.	Injectables – Jacques Corcos, M.D.
	1:45 – 2:05 p.m.	In men – Victor Nitti, M.D.
2:05 – 3:35 p.m.	Behavioral Intervention: Moderator – Kathy Burgio, Ph.D.
	2:05 – 2:20 p.m.	Pelvic Floor Muscle Training – E. Jean Hay-Smith, Ph.D.
	2:20 – 2:35 p.m.	Pelvic Floor Muscle Training (PFMT) and Dose Response – Kari Bo, Ph.D.
	2:35 – 2:50 p.m.	Bladder Training and Urge Control Techniques – Jean Wyman, Ph.D.
	2:50 – 3:05 p.m.	Pessaries – Ingrid Nygaard, M.D.
	3:05 – 3:20 p.m.	Behavioral Training and Urge Suppression – Kathy Burgio, Ph.D.
	3:20 – 3:35 p.m.	Discussion
3:35 – 3:45 p.m.	BREAK
3:45 – 5:00 p.m.	Updates on Current Treatments and Trials: Moderator – J. Christian Winters, M.D.
	3:45 – 4:45 p.m.	PPI: Male Slings/AGUS: Debate
	3:45 – 4:00 p.m.	“Compressed” with Male Slings – Victor Nitti, M.D.
	4:00 – 4:15 p.m.	"Surround" with Artificial Genito – Urinary Sphincter (AGUS ) – Stephen Kraus, M.D.
	4:15 – 4:30 p.m.	“Self-improved” with Conservative TX – Patricia Goode, M.D.
	4:30 – 4:45 p.m.	Rebuttal (3 minutes each)
	4:45 – 5:00 p.m.	Discussion
5:00 – 6:20 p.m.	Acquired LUTS: Pelvic Floor/Pathophysiology/Combined Incontinence Moderator – Dee Fenner, M.D.
	5:00 – 5:20 p.m.	Combined/Dual Urinary and Fecal Incontinence – Dee Fenner, M.D.
	5:20 – 5:40 p.m.	The Role of the Pelvic Floor in the Pathophysiology of Urinary Incontinence in Women; Mechanisms of Disease – John DeLancey, M.D.
	5:40 – 6:00 p.m.	Birth Injuries – John Delancey, M.D.
	6:00 – 6:20 p.m.	Synthetic Meshes – Current and Future – Pam Moalli, M.D., Ph.D.
6:20 – 8:00 p.m.	Announced Prizes: Clinical, Honorable Mention Posters Reception (provided)

Friday, January 9, 2009: 8:00 a.m. – 3:00 p.m.
7:30 – 7:45 a.m.	Announcements: (2) Awards from last night
7:45 – 7:55 a.m.	The Role of International Organizations in the Future of Research Going Forward – Jacques Corcos, M.D.
7:55 – 8:55 a.m.	Acquired LUTS: Neurologic: Moderator – Kenneth Peters, M.D.
	7:55 – 8:10 a.m.	CNS/OAB – Karl Eric Andersson, M.D.
	8:10 – 8:25 a.m.	Spinal Cord Injury – Michael Chancellor, M.D.
	8:25 – 8:40 a.m.	Questions & Answers
	8:40 – 8:55 p.m.	Neuromodulation – Kenneth Peters, M.D.
8:55 – 10:05 a.m.	Treatments Moving Forward: Moderator – Quentin Clemens, M.D.
	8:55 – 9:10 a.m.	Medications: Why Do We Need New Ones? – Quentin Clemens, M.D.
	9:10 – 9:25 a.m.	Regulatory Components FDA – Janine Morris, M.S., Branch Chief
	9:25 – 10:05 a.m.	What Are the Components Necessary to Develop Good Trials Design: Panel:
		9:25 – 9:35 a.m.	Female SUI – Ingrid Nygaard, M.D.
		9:35 – 9:45 a.m.	Male SUI – Brian Flynn, M.D.
		9:45 – 9:55 a.m.	UUI – Roger Dmochowski, M.D.
		9:55 – 10:05 a.m.	Physical Therapy Trials – Mary Pat Fitzgerald, M.D.
10:05 – 10:15 a.m.	BREAK
10:15 – 12:30 p.m.	Future Directions in Research: Moderator –Tom Lue, M.D.
	10:15 – 10:30 a.m.	Tissue Engineering in Skeletal Muscle: Scaffolds – Herman Vandenburgh, Ph.D.
	10:30 – 10:45 a.m.	Bladder Replacement Tissue – Bradley Kropp, M.D.
	10:45 – 11:00 a.m.	Innovations in Animal Models for Fascial Reconstruction – Jan Deprest, M.D., Ph.D.
	11:00 – 11:15 a.m.	Bladder Replacement – Anthony Atala
	11:15 – 11:30 a.m.	Muscle Derived Stem Cells for Stress Urinary Incontinence; North America Clincial Trials – Michael Chancellor, M.D.
	11:30 – 11:45 a.m.	Stem Cells – Tom Lue, M.D.
	11:45 – 12:00 p.m.	Panel: Organs and Tissues – Bradley Kropp, M.D., Jan Deprest, M.D., Ph.D., Anthony Atala, Michael Chancellor, M.D. and Tom Lue, M.D.
	12:00 – 12:30 p.m.	Questions & Answers
12:30 – 1:30 p.m.	LUNCH (provided)
1:30 – 1:50 p.m.	What would Ten Years from Now Look Like? – Roger Dmochowski , M.D.
1:50 – 2:20 p.m.	Brainstorming: Moderator – Deborah Lightner, M.D. Brainstorming Panel – Kari Bo, Ph.D., Linda Brubaker, M.D., Dee Fenner, M.D., J. Christian Winters, M.D., and Ingrid Nygaard, M.D. Brainstorming Discussion and Forum Open Audience
2:20 – 2:30 p.m.	BREAK
2:30 – 3:00 p.m.	Discussion and Forum from the Audience
3:00 – 4:00 p.m.	All moderators to Provide/Present Final Future Directions in a Summation Roundtable discussion on new treatment paradigms. Summary list of what this group thinks we should move forward. Targeted towards summary statements.

DRAFT AGENDA