| Agent Name |
ORGANOPHOSPHATES |
|---|
| Alternative Name |
CLASS |
|---|
| Major Category |
Pesticides |
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| Category |
Organophosphates |
|---|
| Comments |
Organophosphate and carbamate insecticides inhibit a critical enzyme for nerve conduction--acetylcholinesterase. [ATSDR Case Studies # 22] A small number of the organophosphates (OPs) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 572] |
|---|
| Restricted |
EPA is responsible for registering all pesticides in the USA, licensing pesticide applicators, and establishing reentry intervals. Field and pest control workers must wait a specified interval before entering a sprayed area. [ATSDR Case Studies # 22] |
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| Exposure Assessment |
|---|
| BEI |
Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH] |
|---|
| Skin Designation (ACGIH) |
Not evaluated |
|---|
| Half Life |
Few hours to a few days; [TDR, p. 962] Half-lives in the field range from days to months; [ATSDR Case Studies # 22] |
|---|
| Adverse Effects |
|---|
| Neurotoxin |
Motor Neuropathy |
|---|
| Other Poison |
Organophosphate |
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| Links to Other NLM Databases |
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