The Unit of Affective Cognitive Neuroscience examines the dissociable neuro-cognitive systems that mediate emotional responding. The broad goal of this unit is to determine the architecture of these affective systems at the cognitive, neural and neuro-pharmacology levels. To accomplish this goal, the Unit uses neuro-cognitive testing, pharmacological challenge, and fMRI with healthy participants and patient groups. Disorders include: Social Anxiety Disorder, Generalized Anxiety Disorder and psychopathy (in both children and adults). Also, neurological patients whose lesions affect regions of the brain particularly implicated in affective responding. By specifying the neuro-cognitive systems that mediate specific affective functions and by determining the neurochemical properties of these systems, treatment strategies can be developed that focus on the specific systems that are dysfunctional in the specific mood and anxiety disorders under study.

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