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The following information (Health Effects, Handling/Disposal, and Ingredients) is taken from the product label and/or the Material Safety Data Sheet (MSDS) prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS.
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Health Effects
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From MSDS
IMMEDIATE CONCERNS:
- HARMFUL IF SWALLOWED
- CAUSES EYE IRRITATION
- AVOID CONTACT WITH EYES, SKIN OR CLOTHING
- AVOID BREATHING DUST OR SPRAY MIST
- KEEP OUT OF REACH OF CHILDREN
POTENTIAL HEALTH EFFECTS
EYES: This substance is slightly irritating to the eyes. Eye contact may include discomfort, tearing, swelling, redness, and blurred vision.
SKIN: This substance is not expected to cause prolonged or significant skin irritation. If absorbed through the skin, this substance is considered practically non-toxic to internal organs.
INGESTION: This substance is slightly toxic to internal organs if swallowed.
INHALATION: This substance may be irritating if inhaled. Respiratory tract irritation may include, but may not be limited to, one or more of the following: nasal discharge, sore throat, coughing, bronchitis and difficulty in breathing. If inhaled, this substance is considered practically non-toxic to internal organs.
TARGET ORGANS: Acephate is an inhibitor of the cholinesterase enzyme, found in nervous tissue, red blood cells, and plasma.
COMMENTS HEALTH: Depending upon the extent and degree of overexposure to the product, signs and symptoms of cholinesterase inhibition can result following either ingestion, skin contact or inhalation routes of exposure. Signs and symptoms of cholinesterase inhibition can result from either acute (one time), subchronic (repeated short-term) and chronic (daily life-time) overexposure to the product.
Signs and symptoms of cholinesterase inhibition usually occur within 12 hours following overexposure. These effects may include, but may not be limited to, headache, dizziness, weakness, nausea, vomiting, diarrhea, constriction of the pupil of the eye, blurred or dark vision, excessive salivation or nasal discharge, profuse sweating and abdominal cramps. Incontinence, unconsciousness, convulsions and breathing difficulties are indicative of severe poisoning. In untreated severe poisoning, death is due to respiratory failure or cardiac arrest.
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From MSDS
Signs and symptoms of cholinesterase inhibition can result from either acute (one time), subchronic (repeated short-term) and chronic (daily life-time) overexposure to the product.
Signs and symptoms of cholinesterase inhibition usually occur within 12 hours following overexposure. These effects may include, but may not be limited to, headache, dizziness, weakness, nausea, vomiting, diarrhea, constriction of the pupil of the eye, blurred or dark vision, excessive salivation or nasal discharge, profuse sweating and abdominal cramps. Incontinence, unconsciousness, convulsions and breathing difficulties are indicative of severe poisoning. In untreated severe poisoning, death is due to respiratory failure or cardiac arrest.
Acephate increased the incidence of liver tumors in high dose group female mice.
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From MSDS
Acephate was not carcinogenic in male mice, or rats, when tested in two-year feeding studies.
CARCINOGEN: Acephate IRIS Carcinogen Assessment is: C
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From MSDS
EYES: Flush eyes immediately with fresh water for at least 15 minutes while holding the eyelids open. Remove contact lenses if worn. No additional first aid should be necessary. However, if irritation persists, see a doctor.
SKIN: No first aid procedures are required. As a precaution, wash skin thoroughly with soap and water. Remove and wash contaminated clothing.
INGESTION: If swallowed, give a large quantity of water to drink, make person vomit and call a doctor. Never give anything by mouth to an unconscious person.
INHALATION: If respiratory discomfort or irritation occurs, move the person to fresh air. See a doctor if discomfort or irritation continues.
NOTES TO PHYSICIAN: This material contains a cholinesterase inhibitor. Measurement of blood cholinesterase activity may be useful in monitoring exposure. If signs of cholinesterase inhibition appear, atropine sulfate is antidotal. 2-PAM (PROTOPAM) is also antidotal and may be used in conjunction with atropine but should not be used alone.
ADDITIONAL INFORMATION: In case of medical emergencies involving this product, call day or night, (800) 454-2333.
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1 |
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0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe; N = No information provided by manufacturer; * = Chronic Health Hazard |
2001-06-26 |
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Handling/Disposal
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From MSDS
GENERAL PROCEDURES: Keep pesticide in original container. Avoid contamination of feed and foodstuffs. Store in a secure cool, dry place.
ECOTOXICOLOGICAL INFORMATION: This pesticide is toxic to birds. Do not apply directly to water. Do not contaminate water by cleaning of equipment or disposal of wastes. This product is highly toxic to bees exposed to direct treatment or residues on blooming crops or weeds. Do not allow livestock to graze on treated areas. Do not feed treated grass to livestock.
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From MSDS
The Solaris Group is committed to responsible environmental practices and recommends that all of the product be used up, carefully following all label directions and precautions. If necessary to dispose of partially filled product container, then securely wrap it in several layers of newspaper and discard in trash.
EMPTY CONTAINER: Do not reuse empty container. Discard container in trash.
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Ingredients from MSDS/Label
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