| Topic: | hematologic diseases (he) |
| Title: | Pocket Guide to the Diagnosis, Evaluation, and Management of von Willebrand Disease. |
| Author: | n/a |
| Source: | Bethesda, MD: NHLBI Health Information Center. 2008. 15 p. |
| Availability: | Available from NHLBI Health Information Center. PO Box 30105, Bethesda, MD 20824-0105. Email: nhlbiinfo@nhlbi .nih.gov. Website: www.nhlbi.nih.gov. Price: $ 2.00 for single copy; Available free of charge on website. Order No. 08-5833. |
| Abstract: | This pocket guide summarizes guidelines for the diagnosis, evaluation, and management of von Willebrand disease (VWD), an inherited bleeding disorder that is caused by a deficiency or dysfunction of von Willebrand factor (VWF). VWF is a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and also binds and stabilizes blood clotting factor VIII in the circulation. Defects in VWF can cause bleeding by impairing platelet adhesion or by reducing the concentration of blood clotting factor VIII. This brochure offers a summary of the clinical practice guidelines developed by an expert panel convened by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) from the United States Expert Panel. Topics include the initial evaluation of the patient for VWD or other bleeding disorders, laboratory assessment, making the diagnosis of VWD, and management considerations, including general management of VWD patients, treatment of minor bleeding and prophylaxis for minor surgery, treatment of major bleeding and prophylaxis for major surgery, management of menorrhagia and hemorrhagic ovarian cysts in women with VWD, management of pregnancy and childbirth, and caring for patients with acquired von Willebrand syndrome (AVWS). All of the information is presented in figures or tabular format, or bulleted columns, for ease of access. A final section refers readers to the NHLBI Health Information Center at 301–592–8573 or www.nhlbi.nih.gov for more information. 2 figures. 1 table. |
| Format: | Brochure/Pamphlet |
| Language: | English. |
| Major Keywords: | Hematologic Diseases. Von Willebrand Disease. Diagnosis. Symptoms. Risk Factors. Patient Care Management. Guidelines. |
| Minor Keywords: | Coagulation. Blood Diseases and Disorders. Hemorrhage. Menstruation. Diagnostic Tests. Antihemophilic Factor. Monitoring. Pregnancy. Childbirth. |
| Publication Number: | HEBR10058 |
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