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| Topic: |
hematologic diseases (he) |
| Title: |
Chronic Myelogenous Leukemia. |
| Author: |
Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. |
| Source: |
IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 159-212. |
| Availability: |
Available from McGraw Hill. PO Box 182604, Columbus, OH 43272. Phone: 1-877-833-5524. Email: customer .service@mcgraw-hill.com. Website: www.mhprofessional.com . Price: $195.00. |
| Abstract: |
This section on chronic myelogenous leukemia (CML) is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. The authors note that CML is a form of chronic myeloproliferative disease (CMPD) with a well-defined genetic defect, characterized by proliferation in the bone marrow of one or more of the myeloid cell lineages that gradually displaces normal hematopoiesis. This section offers six chapters: epidemiology, risk factors, and classification; molecular biology, pathology, and cytogenetics of CML; the treatment approach to chronic-phase CML; the treatment approach to accelerated-phase or blast-crisis CML; definition of remission, prognosis, and follow-up in patients with CML; and new frontiers in the treatment of relapsed or refractory CML. The chapters include full coverage of all treatment options such as chemotherapy, monoclonal antibodies, and hematopoietic stem cell transplantation. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references. |
| Format: |
Book Chapter |
| Language: |
English. |
| Major Keywords: |
Hematologic Diseases. Cancer. Symptoms. Diagnosis. Pathology. Risk Factors. Diagnostic Tests. Patient Care Management. Cancer Therapy. Leukemia. Chronic Disease. Myeloproliferative Disorders. |
| Minor Keywords: |
Blood Diseases and Disorders. Bone Marrow. Chemotherapy. Epidemiology. Prognosis. Classification. Transplantation. Stem Cells. Etiology. Remission. Recurrence. Acute Disease. |
| Publication Number: |
HEBK10270 |
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