Frederick Faculty Seminar

Description:
Frederick Faculty Seminar

For More Information About This Series Contact:
Susan B. Wester
Phone: 301 846-5865
E-Mail: sbw@mail.ncifcrf.gov
Web:

Series Calendar:
2/25/2009	Denise Whitby	Viruses, MicroRNA and Cancer
2/18/2009	Jairaj Acharya	Sphingolipids: CERT'n Differences Between Insects and Mammals
2/11/2009	Marc Nicklaus	New Chemistry Resources Used in the Quest for HIV-1 Integrase Inhibitors
2/4/2009	Steve Anderson	Endogenous Anti-Sense Transcripts Regulate the Human KIR Gene Cluster
1/28/2009	Ira Daar	EphrinB1 Control of Epithelial Cell-Cell Junctions: Just Par for the Course!
1/21/2009	Terry Yamaguchi	Wnts and the Development of Embryonic and Adult Stem Cells
1/14/2009	Tom Schneider	More Molecular Information Theory
1/7/2009	Joost Oppenheim	HMGB1, Lactoferrin and Granulysin Rapidly "Alarm" Immune Responses
12/17/2008	Mike Dean	Genetics and Therapy for Cancer Stem Cells
12/3/2008	John Coffin	Retrovirus Evolution
11/19/2008	Mike Smith	Current and Future Disease Gene Discoveries Investigating Racial Disparities Using Admixture Mapping
11/12/2008	Art Friedlander	The Yin and Yang of the Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics
11/5/2008	Andy Hurwitz	Understanding T-Cell Responses to Prostate Tumor Antigens
10/29/2008	Wei-Shau Hu	Recombination and Complementation: Two Modes of Interactions Between Human Immunodeficiency Viruses
10/22/2008	Mark Lewandoski	The Role of FGF Signaling in Outgrowth and Patterning of Embryonic Structures
10/1/2008	Ji Ming Wang	G-Protein Coupled Receptors in Cancer and Inflammation
9/17/2008	Dan MacVicar	Multifaceted Regulation of Inflammation by Members of the Triggering Receptors Expressed on Myeloid (TREM)Gene Family
6/25/2008	Shyam Sharan	Too Many Mutations, Too Little Time: Use of Mouse Embryonic Stem Cells to Study Human BRCA 1/2 Variants
6/18/2008	Joe Barchi	Sugars, Peptides and Nanotech: A Winning Combination for Anticancer Research?
6/11/2008	Bruce Shapiro	RNA Nanostructure Design: A New Modality for Nanobiology
6/4/2008	David Waugh	A Toolkit for Protein Expression and Purification in E. Coli and Beyond
5/28/2008	Jeff Gildersleeve	Application of Carbohydrate Microarray Technology to Cancer Research
5/21/2008	Mike Kuehn	New Insights into PML Nuclear Body Function: Integration of SUMO and Ubiquitin Pathways in Regulating Nuclear Protein Turnover
5/7/2008	Alex Wlodawer	We Solved the Structure, but What Can We Say Now About the Function?
4/30/2008	Terry Van Dyke	Deciphering the Complexities of Cancer Pathways and Mechanisms In Vivo
4/23/2008	Frank Maldarelli	Studies of HIV-1 Infection In Vivo
4/9/2008	Ding Jin	Regulation of H. Pylori Growth and Persistence by SpoT or (p)ppGpp
4/2/2008	Stuart Le Grice	Reverse Transcriptase-associated Ribonuclease H: The Tail that Wags the Dog
3/26/2008	Art Friedlander	The Yin and Yang of the Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics
3/19/2008	Ana Gamero	Understanding the Role of STAT2 in Apoptosis, Cancer, and Inflammation
3/12/2008	Grace Yeh	Modulation of Carcinogen Activation and Detoxification by Novel NO-and Dithiolethione-NSAIDs
3/5/2008	George Pavlakis	Interleukin-15: A Kinder, Gentler IL-2 for the Clinic?
2/27/2008	Howard Young	Interferon-Gamma: Mutiple Pathways Regulate Expression
2/20/2008	Esta Sterneck	Life and Death of Mammary Epithelial Cells in the Grip of C/EBP Transcription Factors
2/13/2008	Jeff Strathern	The Consequences of Infidelity (in Biology)
2/6/2008	Yossi Raviv	Identification of Molecular Targets in Biological Membranes by Hydrophobic Photoactivatable Probes
1/30/2008	Cheryl Winkler	Genetic Disparities in Kidney Disease
1/23/2008	Debbie Morrison	Regulation of Raf/MEK/ERK Cascade Signaling
1/16/2008	Doug Reed	CANCELLED-Aerosolized Ebola Zaire in Three Species of Nonhuman Primates: Differences in Disease Course and Pathology
1/9/2008	Robert Blumenthal	HIV-1 Envelope Glycoprotein-Mediated Fusion and Pathogenesis: Implications for Therapy and Vaccine Development
12/12/2007	Mark Fortinl	Membrane Trafficking and Proteolysis in the Notch Developmental SIgnaling Pathway
12/5/2007	Andy Byrd	Exploring Molecular Players in Transcriptional Regulation: Solution Structural Biology of Prokaryotic and Eukaryotic Systems
11/28/2007	Steven Hou	Molecular Genetic Study of Stem Cell Regulation in Drosophila and Mice
11/14/2007	James Kelley	Getting a Charge Out of Chemistry: Making and Using Ions for Bioanalysis
11/7/2007	Sina Bavari	Innate Immune Responses to Highly Pathogenic Microbes
10/31/2007	Eric Freed	HIV-1 Assembly, Release, and Maturation
10/24/2007	David Symer	Variation in Mouse Strains Due to Endogenous Transposition
10/17/2007	Karlyne Reilly	Dissecting Modifiers of Cancer Susceptibility Using Mouse Models of Neurofibromatosis Type 1
10/3/2007	Brad St. Croix	Exploiting the Endothelial Transcriptome for Tumor Vasculature Targeting
9/26/2007	Don Court	A Recombineering Update
9/19/2007	Dennis Klinman	Biology of CpG an Suppressive Oligonucleotides
6/27/2007	Claes Ohlen	Adoptive T Cell Transfer as Therapy Against SIV Infection
6/20/2007	Sina Bavari	CANCELLED-Innate Immune Responses to Highly Pathogenic Microbes
6/13/2007	Alan Rein	Putting the Pieces Together: Studies on HIV-1 Particle Assembly
6/6/2007	Alan Perantoni	Stat Signaling in Kidney Development and Tumorigenesis
5/30/2007	Steve Hughes	HIV-1 RT: Drug Resistance and Drug Design
5/23/2007	Tom Sayers	Sensitizing Tumor Cells to Immune-Mediated Cytotoxicity
5/9/2007	Giorgio Trinchieri	Toll-Like Receptor Signaling in Hematopoietic and Non-Hematopoietic Cells
5/2/2007	Yossef Raviv	CANCELLED--Identification of Molecular Targets in Biological Membranes by Hydrophobic Photoactivatable Probes
4/25/2007	Frank Ruscetti	HTLV-1 Virions: Poorly Infectious No More
4/18/2007	Robert Ulrich	Cell Biology and Proteomic Aspects of Infection by Pathogenic Yersiniae
4/11/2007	Jacek Lubkowski	CCR6-Mediated Chemotaxis by Human Beta-Defensins: Structural Basis
4/4/2007	Barbara Felber	Retroviruses and Retroelements as Tools to Dissect Cellular Gene Expresssion
3/28/2007	Pradman Qasba	Glycosyltransferases and Glycobiology
3/21/2007	Kathrin Muegge	Lsh: Epigenetic Silencing and Beyond
3/14/2007	James Phang	The Metabolism of Proline, an ECM-Derived Stress Substrate, Modulates Carcinogenic Pathways
3/7/2007	Steve O'Brien	A Moving Landscape for Comparative Genomics in Mammals
2/28/2007	Dave Ott	HIV-1 Assembly and the Host Cell
2/21/2007	Dimiter Dimitrov	Human Monoclonal Antibodies Against Viruses and Cancer
2/14/2007	Jim Phang	The Metabolism of Proline, an ECM-Derived Stress Substrate, Modulates Carcinogenic Pathways
2/7/2007	David Garfinkel	Retrotransposons and Their Hosts: An Uneasy Alliance
1/31/2007	Yun-Xing Wang	From Peptide Planes to Sequestering the LRP Receptor in the Cell: The Structure and the Biology of the Receptor-Associated Protein
1/24/2007	Philipp Kaldis	Mouse Models to Study Cell Cycle and Cancer
1/17/2007	Mike Turell	Effects of the Presence of Other Pathogens on the Transmission of Viruses by Mosquitoes
1/10/2007	Amar Klar	Fission Yeast Paradigm Used to Explain Biology of Human Hand-Use Preference, Brain Laterality, Bipolar and Schizophrenia Traits by Selective DNA Strand Segregation in Mitosis
12/13/2006	Allan Weissman	Components of the Ubiquitin System as Potential Targets in Cancer and Metastasis
12/6/2006	Mikhail Kashlev	The Mechanisms Controlling Transcription Fidelity
11/29/2006	Jonathan Keller	The Ids and Outs of Hematopoietic Stem/Progenitor Cell Development
11/15/2006	Larry Keefer	The JS-K Consortium: A Team-Building Approach to Anti-Cancer Drug Development
11/8/2006	Terry Burke	Interfacial Inhibitors of c-Met and ErbB-2 Dependent Signaling
11/1/2006	Lino Tessarollo	Neurotrophins: Growth Factors at the Crossroads of Neurodegeneration and Cancer
10/25/2006	M. Javad Aman	Vector-free Vaccination for Ebola Virus
10/11/2006	Bill Farrar	The Role of IL-6 in Cancer and Epigenetic Gene Silencing
10/4/2006	Rob Gorelick	HIV Nucleocapsid: Involvement in Reverse Transcription and Integration
9/20/2006	Sergei Nedospasov	Physiological Functions of Tumor Necrosis Factor and the Consequences of TNF Ablation: The Farewell Seminar
6/21/2006	Pete Johnson	Control of Cell Proliferation and tumorigenesis by C/EBP Transcription Factors
6/14/2006	Xinhua Ji	The Mechanism of dsRNA Processing by RNase III: How Dicer Dices
6/7/2006	Stuart Austin	Sorting and Segregating the Products of DNA Replication
5/31/2006	Mary Carrington, Ph.D.	The Impact of Variation at the HLA and KIR Gene Clusters on HIV Diseases
5/24/2006	Brad Stiles	Molecular Mimicry Among Bacterial Binary Toxins from Bacillus and Clostridium Species: A Successful Survival Strategy
5/10/2006	Victor Marquez, Ph.D.	Understanding How the Herpes Thymidine Kinase Orchestrates Optimal Sugar and Nucleobase Conformations to Accommodate Its Substrate at the Active Site
5/3/2006	Melinda Hollingshead	The Continuing Need for Animal Models in Drug Development
4/26/2006	Dave Derse, Ph.D.	Human T Cell Leukemia Virus Replication
4/19/2006	Denise Whitby, Ph.D.	KSHV Evolution and Expression of Virally Encoded MicroRNAs
4/12/2006	Nancy Colburn, Ph.D.	Pdcd4 Targets eIF4A to Inhibit Translation, Transcription, Tumorigenesis, and Invasion
4/5/2006	Bill Farrar, Ph.D.	Epigenetic Gene Silencing in Human Multiple Myeloma: A Role for IL-6?
3/29/2006	Sandy Ruscetti	Molecular Basis for the Erythroleukemia Induced by the Friend Spleen Focus-Forming Virus
3/22/2006	Lino Tessarollo	Neurotrophins: Growth Factors at the Cross Road of Neurodegeneration and Cancer
3/15/2006	Vinay Pathak	Mechanisms of HIV-1 Antiviral Drug Resistanace and Host Restriction Factor APOBEC3G
3/8/2006	Scott Durum	Interleukin 7: Mechanisms of Survival and Proliferation in Lymphocytes
3/1/2006	Vineet KewalRamani	HIV Infection: Charting the Inner Passage
2/22/2006	Michael Lerman	Studying The Function of Cancer Genes From Chromosome 3p
2/15/2006	Tom Schneider	Molecular Information Theory: From Clinical Applications to Molecular Machine Efficiency
2/8/2006	Jairaj Acharya	Sphingolipid Metabolism and Signaling in Vivo
2/1/2006	Javad Aman	CANCELLED: Molecular Mechanisms of Ebola Virus Assembly and Release: Lessons for Development of Antiviral Therapeutics
1/25/2006	Jeff Lifson	Monkey Business: Non-Human Primate Models in AIDS Pathogenesis and Vaccine Research
1/18/2006	Ira Daar	EphrinB1 Controls Cell Movement By Runnin' With the Dvl
12/14/2005	Terry Yamaguchi	Wnt Signaling Pathways in Mammalian Development and Disease
12/7/2005	Steve Anderson	Probabilistic Switches
11/30/2005	Dr. Larry Arthur	Inactivated Virus Vaccines
11/16/2005	Mike Dean	Cancer Stem Cells and How to Kill Them
11/9/2005	Joost Oppenheim	The Inflammatory and Painful Consequences of Receptor Cross-Talk
10/19/2005	Stephen Lockett	3D Whole Cell Segmentation and Its Applications
10/12/2005	Ernest Hamel	Antimitotic Peptides and Depsipeptides
10/5/2005	Vineet KewalRamani	HIV Infection: Charting the Inner Passage
6/22/2005	Michael Smith	Disease Gene Discovery Utilizing Mapping by Admixture Linkage Disequilibrium: Progress and Prospects
6/15/2005	Kirk Gustafson	Peptide Natural Products: Twisted Tales of Structure and Function
6/8/2005	Andy Hurwitz	Understanding T Cell Responses to Prostate Cancer: Taking a TRAMP to Task
6/1/2005	Scott McNeil	Pre-Clinical Characterization of Therapeutic and Diagnostic Nanoparticles
5/25/2005	Mark Lewandoski	FGFs, WNTs, and BMPs Conspire to Control Cell Death in the Mouse Embryo
5/11/2005	Wei-Shau Hu	Interactions Between Human Immunodeficiency Viruses: Rates Restrictions, and Implications
5/4/2005	Shyam Sharan	Making Sense of Missense Mutations Identified in BRCA1/2: Time to Get BAC to Work
4/27/2005	Ernest Hamel	Antimitotic Peptides and Depsipeptides
4/20/2005	Dan McVicar	The Triggering Receptors Expressed on Myeloid Cells (TREM): A Receptor Family That Regulates Osteogenesis, Immune Function, and Hemostasis
4/13/2005	Sandra Smith-Gill	Kinetics of Antigen-Antibody Interactions: Implications for Molecular Targeting
4/6/2005	Bruce Shapiro	RNA Conformational Switches: Their Prediction and Analysis
3/30/2005	Bert Zbar	Inherited Human Cancers Caused by Germline Mutations in Kreb's Cycle Genes
3/23/2005	Frank Maldarelli	Studies of HIV-1 Population Genetics in Infected Individuals
2/23/2005	David Covell	Strategies for Mining Screening, Expression, and Structural Information within the NCI-DTP Databases
2/16/2005	Marc Nicklaus	Building a Large-Scale In Silico Screening Resource
2/9/2005	David Newman	Searching Mother Nature's Pharmacopoeia
2/2/2005	Michael Kuehn	Dynamics of Protein Sumoylation and Its Role in Embryonic Development
1/26/2005	Robert Moschel	Tumor Selective Inactivators of O6-Alkylguanine-DNA Alkyltransferase for Improved Chemotherapy
1/19/2005	Sandra Smith-Gill	CANCELLED--Kinetics of Antigen-Antibody Interactions: Implications for Molecular Targeting
1/5/2005	Bruce Shapiro	CANCELLED--RNA Conformational Switches: Their Prediction and Analysis
12/15/2004	Kirk Gustafson	CANCELLED--Peptide Natural Products: Twisted Tales of Structure Analysis
12/8/2004	Jeffery Gildersleeve	Organic Synthesis and Carbohydrate Arrays: Tools for Improving Diagnostic Agents and Vaccines for Cancer
12/1/2004	Nancy Jenkins	Role of the Mitf-Tfe Family of Transcription Factors in Development and Disease
11/17/2004	Bert Zbar	Inherited Human Cancers Caused by Germline Mutations in Kreb's Cycle Genes
11/10/2004	Michael Smith	Disease Gene Discovery Utilizing Mapping by Admixture Linkage Disequilibrium
11/3/2004	David Waugh	Structural Proteomics of Type III Secretion in the Plague Bacillus Yersinia pestis
10/20/2004	Jon Wigginton	Biologic Approaches for the Treatment of Renal Cell Carcinoma and Neuroblastoma
10/13/2004	Ji Ming Wang	The Roles of Formylpeptide Receptors in Inflammation and Cancer
6/23/2004	Ana Gamero	Role of the JAK/Stat Pathway in Type 1 IFN Apoptosis
6/16/2004	Chou-Chi Li	Structure-Function Studies of p97-VCP, an Essential Protein with Many Functions
6/9/2004	Joe Barchi	Sugar-Coated Nanoparticles: Novel Tools as Potential Antimetastatics and Bioimaging Agents
6/2/2004	Stuart LeGrice	Exploiting Nucleoaside Analogs to Probe Reverse Transcription in Retroviruses and LTR-Retrotransposons
5/26/2004	Grace Yeh	Phytochemicals and Cancer Prevention: Role of the Aryl Hydrocarbon Receptor
5/19/2004	Alex Wlodawer	Crystallographic Studies of Proteases-Not So Boring After All
4/28/2004	George Pavlakis	DNA Vaccine Candidates for AIDS
4/21/2004	Esta Steneck	Role of C/EBP Delta in Mammary Gland and Breast Tumor Cell Apoptosis: A p53 Connection
4/14/2004	Howard Young	NK Cells and Their Response to Extracellular Signals
4/7/2004	Ding Jin	The Regulation of Transcription and the Distribution of RNA Polymerase in E. coli
3/31/2004	John Coffin	Evolution of HIV Drug Resistance in Vivo
3/24/2004	Colin Stewart	Nuclear Organization and Function in Development, Aging and Disease
2/25/2004	Karlyne Reilly	Screening for Resistance to Brain Cancer
2/18/2004	David DeShazer	Glanders: New Insights into an Old Disease
2/11/2004	Steven Hou	JAK/STAT Signal Transduction Pathway Regulates Melanotic Tumor Formation and Male Germline Cell Fate in Drosophila
2/4/2004	Jeffrey Strathern	Gene Amplification and Nonhomologous End Joining
1/28/2004	Cheryl Winkler	Human Genetics of Infectious Diseases
1/7/2004	Diana Linnekin	Signaling of Normal and Oncogenic Forms of the Receptor Tyrosine Kinase Kit in Hematopoietic Cells
1/7/2004	Brad St. Croix	Molecular Targets of Tumor Vasculature
12/17/2003	Robert Blumenthal	The HIV/SIV Envelope Glycoprotein-Mediated Membrane Fusion Reaction
12/10/2003	Chris Michejda	Adventures in Drug Design
12/3/2003	Brad St. Croix	Molecular Targets of Tumor Vasculature
11/19/2003	Deborah Morrison	Role of KSR1 in Ras Signaling
11/12/2003	Alan Perantoni	Inductive Signaling in Kidney Development and its Dysregulation in Tumorigenesis
11/5/2003	Michael Turell	Mosquito Vectors of Emerging Diseases: West Nile in the US & Field Studies in the Amazon Basin Region of Peru
10/22/2003	Eric Freed	HIV-1 Assembly and Release
10/15/2003	Andrew Byrd	Structural Biology in Signal Transduction: The Jak/Stat and HGF Pathways
10/8/2003	Sergei Nedospasov	Molecular Gymnastics at TNF/LT Locus in Mice: Roles on TNF and Lymphotoxin Produced by Distinct Cell Types
10/1/2003	Alan Rein	Molecular Interactions in HIV-1 Particle Assembly
6/11/2003	Doug Ferris	Polo Kinases: Critical Regulators of the Cell Cycle
6/4/2003	Don Court	Recombineering: Biology and Technology
5/28/2003	Kazimierz Kasprzak	Chromatin Damage in Nickel-Induced Carcinogenesis
5/21/2003	Pradman Qasba	Galactosyltransferases: Structure-Function and Their Relevance to Diseases
5/7/2003	Kathrin Muegge	Lsh, A Regulator of Epigenetic Modifications
4/30/2003	Jim Kelley	New Life for an "Old" Compound. Preclinical Studies on the Development of Zebularine as an Orally Active Inhibitor of DNA Methyl Transferase
4/23/2003	Mark Fortini	Proteolytic Regulation of Notch Receptor Signaling
4/16/2003	Andy Byrd--CANCELLED	Structural Biology in Signal Transduction: The Jak/Stat and HGF Pathways
4/9/2003	Bob Wiltrout	Coordination of Innate and Adaptive Anti-tumor Immune Responses by IL-12, IL-2, and Stimulation Through CD40
4/2/2003	Mike Turell	Mosquito Vectors of Emerging Diseases: West Nile in the US and Field Studies in the Amazon Basin Region of Peru
3/26/2003	Barbara Felber	Important Mechanisms Regulating Gene Expression
3/19/2003	Neal Copeland	Retroviral Insertional Mutagenesis Provides a Potent Cancer Gene Discovery Tool in the Post-Genome-Sequence Era
3/12/2003	Steve O'Brien	The Human Genes That Restrict HIV/AIDS: Discovery, Implications and Applications
3/5/2003	Tom Sayers	Antitumor Responses In Vivo: A Role for Death Receptors?
2/26/2003	Jim Phang, NCI/Basic Research Lab	The Proline Cycle: From Cell Activation to Apoptosis
2/26/2003	Dr. James Phang	The Proline Cycle: From Cell Activation to Apoptosis
2/19/2003	David Ott, SAIC/Retroviral Assembly Lab	HIV-1 Assembly and Budding
2/12/2003	Jacek Lubkowski, NCI/Macromolecular Crystallography Lab	Structural Studies of the Ligands of CCR6
2/5/2003	Robert Ulrich, LMI/USAMRIID	Interplay of Host Immunity and Bacterial Virulence: All Yet Seems Well
1/29/2003	Dimiter Dimitrov, NCI/Lab of Experimental and Computational Biology	Novel Broadly HIV Neutralizing Human Monoclonal Antibodies
1/29/2003	Dimiter Dimitrov, Ph.D.	Novel Broadly HIV Neutralizing Human Monoclonal Antibodies - Frederick Faculty Seminar Series
1/22/2003	George Beck, NCI/Basic Research Lab	Osteopontin and Nrf2 Are Regulated by Inorganic Phosphate During Osteoblast Differentiation
1/15/2003	Steve Hughes, NCI/Retroviral Replication Lab	HIV-1 Reverse Transcriptase: Mechanisms of Nucleotide Analog Resistance
1/15/2003	Dr. Steve Hughes	HIV-1 Reverse Transcriptase: Mechanisms of Nucleotide Analog Resistance
12/11/2002	Tom Sayers, NCI/Lab of Experimental Immunology	Immune-Mediated Mechanisms of Tumor Destruction