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Selected Publications

Comparative Pathobiology Group

1997–2008

  1. Yu L, Saile K, Swartz CD , He H , Zheng X, Kissling GE , Di X, Lucas S, Robboy SJ, Dixon D. (2008). Differential expression of Receptor Tyrosine Kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas. Molecular medicine (Cambridge, Mass.) 14(5-6):264-275. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18231572) Exit NIEHS
  2. Moore AB, Flake GP, Swartz CD, Heartwell G, Cousins D, Haseman JK, Kissling GE, Sidawy MK, and Dixon D. (2008). Association of Race, Age and Body Mass Index with Gross Pathology of Uterine Leiomyomas. J Reprod Med 53:90-96. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18357799?ordinalpos=&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.SmartSearch&log$=citationsensor) Exit NIEHS
  3. Yu L, Saile K, Swartz CD, He H, Zheng X, Kissling GE, Di X, Lucas S, Robboy SJ, and Dixon D. (2008). Differential Expression of Receptor Tyrosine Kinases (RTKs) and IGF-I Pathway Activation in Human Uterine Leiomyomas. Mol Med 14:264-275. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18231572?ordinalpos=30&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  4. Dixon D, Herbert R, Kissling GE, Brix A, Miller R, and Maronpot RR. (2008). Summary of Chemically Induced Pulmonary Lesions in the National Toxicology Program (NTP) Toxicology and Carcinogenesis Studies. Toxicologic Pathol 36:428-39. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18441259?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  5. Smoak K, Madenspacher J, Jeyaseelan S, Williams B, Dixon D, Poch KR, Nick JA, Worthen GS, and Fessler MB. (2008). Effects of Liver X Receptor Agonist Treatment on Pulmonary Inflammation and Host Defense. J Immunol 180:3305-12. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18292555?ordinalpos=&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.SmartSearch&log$=citationsensor) Exit NIEHS
  6. Veit AC, Painter JT, Miller R, Hardisty JF, and Dixon D. (2008). Characterization of Uterine Granular Cell Tumors in B6C3F1 Mice: A Histomorphological, Immunohistochemical, and Ultrastructural Study. Vet Pathol 45:654-62. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18725470?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  7. Di X, Yu L, Moore AB, Castro L, Zheng X, Hermon T, and Dixon D. (2008). A Low Concentration of Genistein Induces Estrogen Receptor-Alpha and Insulin-like Growth Factor-I Receptor Interactions and Proliferation in Uterine Leiomyoma Cells. Human Reprod 23:1873-83. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18492705?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  8. Hermon TL, Moore AB, Yu L, Kissling GE, Castora FJ, and Dixon D. (2008). Estrogen Receptor Alpha (ERalpha) Phospho-Serine-188 is Highly Expressed in Human Uterine Leiomyomas Compared to Matched Myometrium. Virchows Arch [Epub ahead of print] [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18853184?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  9. Moore AB, Castro L, Yu L, Zheng X, Di X, Sifre M, Kissling GE, Newbold RR, Bortner CD, and Dixon D. (2007). Stimulatory and Inhibitory Effects of Genistein on Human Uterine Leiomyoma Cell Proliferation are Influenced by the Concentration. Hum Reprod 22(10):2623-2631.  [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17725991&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)Exit NIEHS
  10. Moore AB, Flake GP, Swartz CD, Heartwell G, Cousins D, Haseman JK, Kissling GE, Sidawy MK, and Dixon D. (2007). Associations of Race, Age and Body Weight (BMI) on Gross Pathology Parameters of Uterine Leiomyomas. (In Press; J Reprod Med).
  11. Tilley SL,  Stapleton C,  Jaradat M, Dixon D,  Hua X,  Erikson CJ, McCaskill JG, Chason KD, Liao, G,  Jania L, Koller BH, and Jetten AM. (2007). Retinoid-related Orphan Receptor (ROR) γ Controls Immunoglobulin Productio and Th1/Th2 Cytokine Balance in the Adaptive Immune Response to Allergen. J Immunol 178:3208-18. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17312169)  Exit NIEHS
  12. Jaradat M, Stapleton C, Dixon D, Tilley SL, Erikson CJ, McCaskill JG, Kang HS, Angers M, Liao G, Collins J, Grissom S, and  Jetten AM. (2006). Modulatory role for retinoid-related orphan receptor alpha (RORa) in allergen-induced lung inflammation. Am J Respir Crit Care Med 174(12):1299-1309. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16973978)  Exit NIEHS
  13. Varella-Garcia M, Chen L, Zheng X, Yu L, and Dixon D. (2006). Karyotypic characteristics of human uterine leiomyoma and myometrial cell lines following telomerase induction. Cancer Genet Cytogenet 170(1):71-5. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16965960)  Exit NIEHS
  14. Dixon D, Parrott EC, Segars JH, Olden K, and Pinn VW. (2006). The second National Institutes of Health International Congress on advances in uterine leiomyoma research: conference summary and future recommendations. Fertil Steril 86(4):800-6. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17027353)  Exit NIEHS
  15. Bauer AK, Dixon D, DeGraff LM, Cho HY, Walker CR, Malkinson AM, and Kleeberger SR. (2005). Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis. J Natl Cancer Inst 97(23):1778-81. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16333033)  Exit NIEHS
  16. Aoyama H, Couse JF, Hewitt, SC, Haseman, JK, He H, Zheng X, Majstoravich S, Korach KS, and Dixon, D. (2005). Upregulation of Estrogen Receptor Expression in the Uterus of Ovariectomized B6C3F1 Mice and Ishikawa Cells Treated with Bromoethane. Toxicol And Appl Pharmacol 209(3):226-235. [Abstract] ()http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15922381  Exit NIEHS
  17. Swartz CD, Afshari CA, Yu L, Hall KE, and Dixon D. (2005). Estrogen-induced changes in IGF-I, Myb family and MAP kinase pathway genes in human uterine leiomyoma and normal uterine smooth muscle cell lines. Mol Hum Reprod. 11(6):441-50. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15879465)  Exit NIEHS
  18. Stapleton C, Jaradat M, Dixon D, Kim S-C, Liao G, Cristiano J, Moorman MP, and Jetten AM. (2005). Enhanced susceptibility of Staggerer (RORasg/sg) to lipopolysaccharide-induced airway inflammation. Am J Physiol Lung Cell Mol Physiol 289: L144-152. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15778248)  Exit NIEHS
  19. Hoffler U, Dixon D, Peddada S, and Ghanayem BI. (2005). Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice. Mutation Research 572: 58-72. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15790490)  Exit NIEHS
  20. Boorman G, Dixon D, Elwell M, Kerlin R, Morton D, Peters T, Regan K, and Sullivan J. (2004). STP Hyperplasia Working Group Society of toxicologic pathology position on assessment of hyperplastic lesions in rodent carcinogenicity. Toxicol Pathol 32(1): 124-125. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14713557)  Exit NIEHS
  21. Daniely Y, Liao G, Dixon D, Lionnoila RI, Oren M, and Jetten AM. (2004). Critical Role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol 287:C171-181. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15189821)  Exit NIEHS
  22. Nikitin AY, Alcaraz A, Anver MR, Bronson RT, Cardiff RD, Dixon D, Fraire AE, Gabrielson EW, Gunning WT, Haines DC, Kaufman MT, Linnoila RI, Maronpot RR, Rabson AS, Reddick RL, Rehm S, Rozengurt N, Schuller HM, Shmidt EN, Travis WD, Ward JM, and Jacks T. (2004). Boston Recommendations for Classification of Pulmonary Proliferative Lesions of the Mouse. Cancer Res 64:2307-2316. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15059877)  Exit NIEHS
  23. Mozzachio K, Linder K, and Dixon D. (2004). Uterine smooth muscle tumors in potbellied pigs (Sus scrofa) resemble human fibroids: a potential animal model. Toxicol Pathol 32(4):402-7. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15307213)  Exit NIEHS
  24. Vaidya VS, Shankar K, Dixon D, Lock EA, and Mehendale HM. (2003). Mechanisms of stimulated tissue repair in survival from acute renal tubular necrosis: Role of mapk pathway. Toxicol Sci 72(1): 45 Suppl. S.
  25. Boorman G, Dixon D, Elwell M, Kerlin R, Morton D, Peters T, Regan K, and Sullivan J. (2003). Assessment of hyperplastic lesions in rodent carcinogenicity studies. Toxicol Pathol 31(6): 709-710. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14585740)  Exit NIEHS
  26. Vaidya VS, Shankar K, Lock EA, Dixon D, and Mehendale HM. (2003). Molecular mechanisms of renal tissue repair in survival from acute renal tubule necrosis: Role of ERK1/2 pathway. Toxicol Pathol 31(6): 604-618. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14585728)  Exit NIEHS
  27. Picut CA, Aoyama H, Holder JW, Gold LS, Maronpot RR, and Dixon D. (2003). Bromoethane, chloroethane and ethylene oxide induced uterine neoplasms in B6C3F1 mice from 2-year NTP inhalation bioassays: pathology and incidence data revisited. Exp Toxicol Pathol 55(1): 1-9. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12940622)  Exit NIEHS
  28. Flake GP, Andersen J, and Dixon D. (2003). Etiology and pathogenesis of uterine leiomyomas: A review. Environ Health Perspect 111(8): 1037-1054. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12826476)  Exit NIEHS
  29. Carney SA, Tahara H, Swartz CD, Risinger JI, He H, Moore AB, Haseman K, Barrett JC, and Dixon D. (2002). Immortalization of human uterine leiomyomas and myometrial cell lines after induction of telomerase activity: Molecular and phenotype characteristics. Lab Invest 82(6): 719-728. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12065682)  Exit NIEHS
  30. Mehta DV, Kim YS, Dixon D, and Jetten AM. (2002). Characterization of the expression of the retinoid-related, testis-associated receptor (RTR) in trophoblasts. Placenta 23(4): 281-287. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11969338)  Exit NIEHS
  31. Newbold RR, Moore AB, and Dixon D. (2002). Characterization of uterine leiomyomas in CD-1 mice following developmental exposure to diethylstilbestrol (DES). Toxicol Pathol 30(5): 611-616. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12371671)  Exit NIEHS
  32. Dixon D, Flake GP, Moore AB, He H, Haseman JK, Risinger JI, Lancaster JM, Berchuck A, Barrett JC, and Robboy SJ. (2002). Cell proliferation and apoptosis in human uterine leiomyomas and myometria. Virchows Arch 441(1): 53-62. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12111201)  Exit NIEHS
  33. Couse JF, Dixon D, Yates M, Moore AB, Ma L, Maas R, and Korach KS. (2001). Estrogen receptor-alpha knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract. Dev Biol 238(2): 224-238. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11784006)  Exit NIEHS
  34. Newbold RR, DiAugustine RP, Risinger JI, Everitt JI, Walmer DK, Parrott EC, and Dixon D. (2000). Advances in uterine leiomyoma research: Conference overview, summary, and future research recommendations. Environ Health Persp 108: 769-773 Suppl. 5. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11035980)  Exit NIEHS
  35. Dixon D, He H, and Haseman JK. (2000). Immunohistochemical localization of growth factors and their receptors in uterine leiomyomas and matched myometrium. Environ Health Persp 108: 795-802 Suppl. 5. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11035985)  Exit NIEHS
  36. Moore AB, He H, Yoshida A, Rico PJ, Haseman JK, and Dixon D. (2000). Transforming growth factor-alpha, epidermal growth factor receptor, and PCNA immunoexpression in uterine leiomyosarcomas and leiomyomas in B6C3F1 mice. Exp Toxicol Pathol 52(3): 195-200. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10930119)  Exit NIEHS
  37. Yoshida A, Newbold RA, and Dixon D. (2000). Abnormal cell differentiation and p21 expression of Endometrial Epithelial Cells following developmental exposure to Diethylstilbestrol (DES). Toxicol Pathol 28:237-245. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10805141)  Exit NIEHS
  38. Yoshida A, Newbold RA, and Dixon D. (1999). Effects of Neonatal Diethylstilbestrol (DES) Exposure on Morphology and Growth Patterns of Endometrial Epithelial Cells in CD-1 mice. Toxicol Pathol 27:325-333. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10356709)  Exit NIEHS
  39. Baird DD, Schectman JM, Dixon D, Sandler DP, and Hill MC. (1998). African Americans at higher risk than whites for uterine fibroids: Ultrasound evidence. Am J Epidemiol 147(11): 358 Suppl. S.
  40. Goelz MF, Dixon D, Myers PH, Clark JA, and Forsythe DB. (1998). Ganglioneuroma in the adrenal gland of a rat. Contemp Top Lab Anim 37(2): 75-77. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12456176)  Exit NIEHS
  41. Trukhanova LS, Hong HHL, Sills RC, Bowser AD, Gaul B, Boorman GA, Turusov VS, Devereux TR, and Dixon D. (1998). Predominant p53 G -> A transition mutation and enhanced cell proliferation in uterine sarcomas of CBA mice treated with 1,2-dimethylhydrazine. Toxicol Pathol 26(3): 367-374. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9608642)  Exit NIEHS
  42. Dixon D, Couse JF, and Korach KS. (1997). Disruption of the estrogen receptor gene in mice. Toxicol Pathol 25(5): 518-520. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9323845)  Exit NIEHS
  43. Packenham JP, duManoir S, Schrock E, Risinger JI, Dixon D, Denz DN, Evans JAC, Berchuck A, Barrett JC, Devereux TR, and Ried T. (1997). Analysis of genetic alterations in uterine leiomyomas and leiomyosarcomas by comparative genomic hybridization. Mol Carcinogen 19(4): 273-279. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9290705)  Exit NIEHS
  44. Aoyama H, Kato H, and Dixon D. (1997). Specificity of antibodies against rodent transforming growth factor-alpha protein. J Histochem Cytochem 45(5): 695-701. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=915415)  Exit NIEHS

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Last Reviewed: December 07, 2008