Summaries & Associations of Study Results
TR-311 Tetrachloroethylene
Target Organs and Levels of Evidence
NTP Technical Report Number 311
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| TETRACHLOROETHYLENE 127-18-4 |
08/14/85 | DRY-CLEANING SOLVENT, METAL DEGREASER, INTERMEDIATE, TEXTILE PROCESSING, ANTIHELMINTIC (MERCK 1989) | Inhalation R: 0,200,400, M: 0,100,200 PPM/50 PER GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | HEMATOPOIETIC SYSTEM: LEUKEMIA 28/50 37/50 37/50 | |||
| KIDNEY TUBULAR CELL: ADENOMA 1/49 3/49 2/50 OR ADENOCARCINOMA 0/49 0/49 2/50 COMBINED 1/49 3/49 4/50 | ||||
| FR: SOME EVIDENCE | HEMATOPOIETIC SYSTEM: LEUKEMIA 18/50 30/50 29/50 | |||
| MM: CLEAR EVIDENCE | LIVER: ADENOMA 11/49 8/49 18/50; CARCINOMA 7/49 25/49 26/50 | |||
| FM: CLEAR EVIDENCE | LIVER: CARCINOMA 1/48 13/50 36/50 | |||
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